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In recent years, magnetic particle spectroscopy (MPS) has become a highly sensitive and versatile sensing technique for quantitative bioassays. It relies on the dynamic magnetic responses of magnetic nanoparticles (MNPs) for the detection…

Nowadays, there is a growing interest in the field of magnetic particle spectroscopy (MPS)-based bioassays. MPS monitors the dynamic magnetic response of surface-functionalized magnetic nanoparticles (MNPs) upon excitation by an alternating…

Systems and Control · Electrical Eng. & Systems 2022-11-14 Vinit Kumar Chugh , Arturo di Girolamo , Venkatramana D. Krishna , Kai Wu , Maxim C-J Cheeran , Jian-Ping Wang

Nanomaterials, in addition to their small size, possess unique physicochemical properties that differ from the bulk materials, making them ideal for a host of novel applications. Magnetic nanoparticle (MNP) is one important class of…

Applied Physics · Physics 2019-10-08 Kai Wu , Diqing Su , Jinming Liu , Renata Saha , Jian-Ping Wang

Magnetic particle spectroscopy (MPS), also called magnetization response spectroscopy, is a novel measurement tool derived from magnetic particle imaging (MPI). It can be interpreted as a zero-dimensional version of MPI scanner. MPS was…

Applied Physics · Physics 2020-03-24 Kai Wu , Diqing Su , Renata Saha , Jinming Liu , Vinit Kumar Chugh , Jian-Ping Wang

Magnetic particle spectroscopy (MPS) is one of the most versatile methods to characterize the magnetic properties of magnetic nanoparticles (MNPs). The excitation magnetic field is one of the most crucial factors that affects the MPS signal…

Applied Physics · Physics 2023-04-25 Shaoqi Sun , Shijie Sun , Lijun Xu , Jing Zhong

Magnetic nanoparticles (MNPs) have been extensively used as contrasts and tracers for bioimaging, heating sources for tumor therapy, carriers for controlled drug delivery, and labels for magnetic immunoassays. Here, we describe a MNP…

Applied Physics · Physics 2019-09-11 Kai Wu , Jinming Liu , Diqing Su , Renata Saha , Jian-Ping Wang

Magnetic nanoparticles (MNPs) with proper surface functionalization have been extensively applied as labels for magnetic immunoassays, carriers for controlled drug/gene delivery, tracers and contrasts for magnetic imaging, etc. Here, we…

Magnetic nanoparticles (MNPs) form the foundation of many technologies, frequently serving to purify proteins or cells from a biological sample or to remove environmental contaminants. Their success relies on their magnetic response, which…

Instrumentation and Detectors · Physics 2025-06-18 Alexis Scholtz , Jack Paulson , Victoria Nunez , Andrea M. Armani

In this work, we report a 5-minute magnetic particle spectroscopy (MPS)-based bioassay strategy. In our approach, surface functionalized magnetic nanoparticles (MNPs) are incubated with target analytes at 37 {\deg}C with agitation for 3…

Nowadays, there is an increasing demand for more accessible routine diagnostics for patients with respect to high accuracy, ease of use, and low cost. However, the quantitative and high accuracy bioassays in large hospitals and laboratories…

Hyperpolarized nuclear magnetic resonance and lab-on-a-chip microfluidics are two dynamic, but until recently quite distinct, fields of research. Recent developments in both areas increased their synergistic overlap. By microfluidic…

Chemical Physics · Physics 2021-09-29 James Eills , William Hale , Marcel Utz

Magnetic nanoparticles (MNPs) are the foundation of several new strategies for neural repair and neurological therapies. The fact that a remote force can act on MNPs at the cytoplasmic space constitutes the essence of many new…

Neurons and Cognition · Quantitative Biology 2024-02-22 Gerardo F. Goya , Vittoria Raffa

Magnetic nanoparticles (MNPs) derived from the Massart coprecipitation method have played a pioneering role in bridging materials science and biology. Their magnetic moment and nanoscale dimensions have long enabled applications in magnetic…

Soft Condensed Matter · Physics 2025-12-02 Myriam Reffay , Gilles Tessier , Jean-François Berret

Magnetic particle imaging (MPI) is a non-invasive, non-ionizing imaging technique for the visualization and quantification of magnetic nanoparticles (MNPs). The technique is especially suitable for cell imaging as it offers zero background…

In nanopore technology, the development of multiplexed detection and release platforms with high spatial and temporal resolution remains a significant challenge due to the difficulty in distinguishing signals originating from different…

Applied Physics · Physics 2025-10-16 Ali Douaki , Shukun Weng , Silvia Dante , Nako Nakatsuka , Makusu Tsutsui , Roman Krahne , Denis Garoli

This Letter is a micromagnetic simulation-based study on the GHz-frequency ferromagnetic resonances for the detection of magnetic nanoparticles (MNPs) using spin current nano-oscillator (SCNO) operating in precession mode as a spintronic…

Applied Physics · Physics 2019-10-01 Renata Saha , Kai Wu , Diqing Su , Jian-Ping Wang

Magnetic nanoparticles offer unique potential for various technological, biomedical, or environmental applications thanks to the size-, shape- and material-dependent tunability of their magnetic properties. To optimize particles for a…

Magnetic Particle Imaging (MPI) has been successfully used to visualize the distribution of superparamagnetic nanoparticles within 3D volumes with high sensitivity in real time. Since the magnetic field topology of MPI scanners is well…

Magnetic nanoparticles (MNPs) have been extensively used as tiny heating sources in magnetic hyperthermia therapy, contrast agents in magnetic resonance imaging (MRI), tracers in magnetic particle imaging (MPI), carriers for drug/gene…

Applied Physics · Physics 2021-06-16 Kai Wu , Jinming Liu , Renata Saha , Chaoyi Peng , Diqing Su , Andrew Yongqiang Wang , Jian-Ping Wang

Nanoparticles (NPs) engineered for biomedical applications are meant to be in contact with protein-rich physiological fluids. These proteins are usually adsorbed onto the NP surface, forming a swaddling layer called protein corona that…

Biological Physics · Physics 2014-07-01 M. P. Catalayud , B. Sanz , V. Raffa , C. Riggio , M. R. Ibarra , G. F. Goya
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