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The alignment of serial-section electron microscopy (ssEM) images is critical for efforts in neuroscience that seek to reconstruct neuronal circuits. However, each ssEM plane contains densely packed structures that vary from one section to…

Computer Vision and Pattern Recognition · Computer Science 2017-12-06 Inwan Yoo , David G. C. Hildebrand , Willie F. Tobin , Wei-Chung Allen Lee , Won-Ki Jeong

Image registration is used in many medical image analysis applications, such as tracking the motion of tissue in cardiac images, where cardiac kinematics can be an indicator of tissue health. Registration is a challenging problem for deep…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Benjamin Graham

Image registration techniques usually assume that the images to be registered are of a certain type (e.g. single- vs. multi-modal, 2D vs. 3D, rigid vs. deformable) and there lacks a general method that can work for data under all…

Image and Video Processing · Electrical Eng. & Systems 2025-01-28 Quang Luong Nhat Nguyen , Ruiming Cao , Laura Waller

Deformation field estimation is an important and challenging issue in many medical image registration applications. In recent years, deep learning technique has become a promising approach for simplifying registration problems, and has been…

Computer Vision and Pattern Recognition · Computer Science 2020-04-17 Yujia Zhou , Shumao Pang , Jun Cheng , Yuhang Sun , Yi Wu , Lei Zhao , Yaqin Liu , Zhentai Lu , Wei Yang , Qianjin Feng

Deformable image registration (DIR) is essential for many image-guided therapies. Recently, deep learning approaches have gained substantial popularity and success in DIR. Most deep learning approaches use the so-called mono-stream…

Image and Video Processing · Electrical Eng. & Systems 2020-12-08 Zhe Xu , Jie Luo , Jiangpeng Yan , Xiu Li , Jagadeesan Jayender

Pathologists need to combine information from differently stained pathology slices for accurate diagnosis. Deformable image registration is a necessary technique for fusing multi-modal pathology slices. This paper proposes a hybrid deep…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Chulong Zhang , Yuming Jiang , Na Li , Zhicheng Zhang , Md Tauhidul Islam , Jingjing Dai , Lin Liu , Wenfeng He , Wenjian Qin , Jing Xiong , Yaoqin Xie , Xiaokun Liang

Image registration with deep neural networks has become an active field of research and exciting avenue for a long standing problem in medical imaging. The goal is to learn a complex function that maps the appearance of input image pairs to…

Computer Vision and Pattern Recognition · Computer Science 2019-07-23 Matthew C. H. Lee , Ozan Oktay , Andreas Schuh , Michiel Schaap , Ben Glocker

We present VoxelMorph, a fast learning-based framework for deformable, pairwise medical image registration. Traditional registration methods optimize an objective function for each pair of images, which can be time-consuming for large…

Computer Vision and Pattern Recognition · Computer Science 2019-09-04 Guha Balakrishnan , Amy Zhao , Mert R. Sabuncu , John Guttag , Adrian V. Dalca

Image registration, the process of aligning two or more images, is the core technique of many (semi-)automatic medical image analysis tasks. Recent studies have shown that deep learning methods, notably convolutional neural networks…

Computer Vision and Pattern Recognition · Computer Science 2021-09-09 Bob D. de Vos , Floris F. Berendsen , Max A. Viergever , Hessam Sokooti , Marius Staring , Ivana Isgum

Deformable image registration poses a challenging problem where, unlike most deep learning tasks, a complex relationship between multiple coordinate systems has to be considered. Although data-driven methods have shown promising…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Vasiliki Sideri-Lampretsa , Nil Stolt-Ansó , Huaqi Qiu , Julian McGinnis , Wenke Karbole , Martin Menten , Daniel Rueckert

Image registration (IR) is a process that deforms images to align them with respect to a reference space, making it easier for medical practitioners to examine various medical images in a standardized reference frame, such as having the…

Image and Video Processing · Electrical Eng. & Systems 2024-01-11 Ahmad Hammoudeh , Stéphane Dupont

Purpose: Diffeomorphic image registration is essential in many medical imaging applications. Several registration algorithms of such type have been proposed, but primarily for intra-contrast alignment. Currently, efficient…

Image and Video Processing · Electrical Eng. & Systems 2022-09-14 Nima Masoumi , Hassan Rivaz , M. Omair Ahmad , Yiming Xiao

Intensity-based image registration approaches rely on similarity measures to guide the search for geometric correspondences with high affinity between images. The properties of the used measure are vital for the robustness and accuracy of…

Computer Vision and Pattern Recognition · Computer Science 2019-02-22 Johan Öfverstedt , Joakim Lindblad , Nataša Sladoje

Recently, deep-learning-based approaches have been widely studied for deformable image registration task. However, most efforts directly map the composite image representation to spatial transformation through the convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2022-07-08 Jiashun Chen , Donghuan Lu , Yu Zhang , Dong Wei , Munan Ning , Xinyu Shi , Zhe Xu , Yefeng Zheng

Deformable image registration is fundamental to longitudinal and population analysis. Geometric alignment of the infant brain MR images is challenging, owing to rapid changes in image appearance in association with brain development. In…

Computer Vision and Pattern Recognition · Computer Science 2020-07-07 Dongming Wei , Sahar Ahmad , Yunzhi Huang , Lei Ma , Zhengwang Wu , Gang Li , Li Wang , Qian Wang , Pew-Thian Yap , Dinggang Shen

This paper presents a novel predictive model, MetaMorph, for metamorphic registration of images with appearance changes (i.e., caused by brain tumors). In contrast to previous learning-based registration methods that have little or no…

Computer Vision and Pattern Recognition · Computer Science 2023-03-10 Jian Wang , Jiarui Xing , Jason Druzgal , William M. Wells , Miaomiao Zhang

We present KeyMorph, a deep learning-based image registration framework that relies on automatically detecting corresponding keypoints. State-of-the-art deep learning methods for registration often are not robust to large misalignments, are…

Computer Vision and Pattern Recognition · Computer Science 2023-09-04 Alan Q. Wang , Evan M. Yu , Adrian V. Dalca , Mert R. Sabuncu

Spatially varying regularization accommodates the deformation variations that may be necessary for different anatomical regions during deformable image registration. Historically, optimization-based registration models have harnessed…

Computer Vision and Pattern Recognition · Computer Science 2025-11-21 Junyu Chen , Shuwen Wei , Yihao Liu , Zhangxing Bian , Yufan He , Aaron Carass , Harrison Bai , Yong Du

Current approaches for deformable medical image registration often struggle to fulfill all of the following criteria: versatile applicability, small computation or training times, and the being able to estimate large deformations.…

Image and Video Processing · Electrical Eng. & Systems 2021-12-07 Hanna Siebert , Lasse Hansen , Mattias P. Heinrich

This paper introduces GeoMorph, a novel geometric deep-learning framework designed for image registration of cortical surfaces. The registration process consists of two main steps. First, independent feature extraction is performed on each…

Machine Learning · Computer Science 2023-11-23 Mohamed A. Suliman , Logan Z. J. Williams , Abdulah Fawaz , Emma C. Robinson
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