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Image registration is an essential step in many medical image analysis tasks. Traditional methods for image registration are primarily optimization-driven, finding the optimal deformations that maximize the similarity between two images.…

Computer Vision and Pattern Recognition · Computer Science 2024-10-14 Shanlin Sun , Kun Han , Chenyu You , Hao Tang , Deying Kong , Junayed Naushad , Xiangyi Yan , Haoyu Ma , Pooya Khosravi , James S. Duncan , Xiaohui Xie

We introduce SparseVM, a method that registers clinical-quality 3D MR scans both faster and more accurately than previously possible. Deformable alignment, or registration, of clinical scans is a fundamental task for many clinical…

Computer Vision and Pattern Recognition · Computer Science 2020-04-07 Kathleen M. Lewis , Natalia S. Rost , John Guttag , Adrian V. Dalca

This paper introduces Quicksilver, a fast deformable image registration method. Quicksilver registration for image-pairs works by patch-wise prediction of a deformation model based directly on image appearance. A deep encoder-decoder…

Computer Vision and Pattern Recognition · Computer Science 2017-07-21 Xiao Yang , Roland Kwitt , Martin Styner , Marc Niethammer

Image registration is a fundamental step in medical image analysis. Ideally, the transformation that registers one image to another should be a diffeomorphism that is both invertible and smooth. Traditional methods like geodesic shooting…

Computer Vision and Pattern Recognition · Computer Science 2019-07-02 Dongyang Kuang

Deformable image registration aims to precisely align medical images from different modalities or times. Traditional deep learning methods, while effective, often lack interpretability, real-time observability and adjustment capacity during…

Computer Vision and Pattern Recognition · Computer Science 2024-10-08 Yongtai Zhuo , Yiqing Shen

In this paper, we propose a deep learning approach for image registration by predicting deformation from image appearance. Since obtaining ground-truth deformation fields for training can be challenging, we design a fully convolutional…

Computer Vision and Pattern Recognition · Computer Science 2018-02-14 Jingfan Fan , Xiaohuan Cao , Pew-Thian Yap , Dinggang Shen

Deep diffeomorphic registration faces significant challenges for high-dimensional images, especially in terms of memory limits. Existing approaches either downsample original images, or approximate underlying transformations, or reduce…

Image and Video Processing · Electrical Eng. & Systems 2021-05-25 Ankita Joshi , Yi Hong

Image registration has traditionally been done using two distinct approaches: learning based methods, relying on robust deep neural networks, and optimization-based methods, applying complex mathematical transformations to warp images…

Computer Vision and Pattern Recognition · Computer Science 2024-01-22 Gabriel De Araujo , Shanlin Sun , Xiaohui Xie

Nonlinear image registration continues to be a fundamentally important tool in medical image analysis. Diagnostic tasks, image-guided surgery and radiotherapy as well as motion analysis all rely heavily on accurate intra-patient alignment.…

Computer Vision and Pattern Recognition · Computer Science 2019-07-26 Mattias P. Heinrich

Deformable registration consists of finding the best dense correspondence between two different images. Many algorithms have been published, but the clinical application was made difficult by the high calculation time needed to solve the…

Computer Vision and Pattern Recognition · Computer Science 2021-11-25 Théo Estienne , Maria Vakalopoulou , Enzo Battistella , Theophraste Henry , Marvin Lerousseau , Amaury Leroy , Nikos Paragios , Eric Deutsch

We describe a diffeomorphic registration algorithm that allows groups of images to be accurately aligned to a common space, which we intend to incorporate into the SPM software. The idea is to perform inference in a probabilistic graphical…

Computer Vision and Pattern Recognition · Computer Science 2021-05-10 Mikael Brudfors , Yaël Balbastre , Guillaume Flandin , Parashkev Nachev , John Ashburner

Deformable image registration and regression are important tasks in medical image analysis. However, they are computationally expensive, especially when analyzing large-scale datasets that contain thousands of images. Hence, cluster…

Computer Vision and Pattern Recognition · Computer Science 2017-11-17 Zhipeng Ding , Greg Fleishman , Xiao Yang , Paul Thompson , Roland Kwitt , Marc Niethammer

Deformable image registration (DIR), aiming to find spatial correspondence between images, is one of the most critical problems in the domain of medical image analysis. In this paper, we present a novel, generic, and accurate diffeomorphic…

Computer Vision and Pattern Recognition · Computer Science 2023-02-08 Yifan Wu , Tom Z. Jiahao , Jiancong Wang , Paul A. Yushkevich , M. Ani Hsieh , James C. Gee

Deep learning has emerged as a strong alternative for classical iterative methods for deformable medical image registration, where the goal is to find a mapping between the coordinate systems of two images. Popular classical image…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Joel Honkamaa , Pekka Marttinen

This work proposes a multimodal diffeomorphic registration method using Neural Ordinary Differential Equations (Neural ODEs). Nonrigid registration algorithms exhibit tradeoffs between their accuracy, the computational complexity of their…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Salvador Rodriguez-Sanz , Monica Hernandez

Deep learning technologies have dramatically reshaped the field of medical image registration over the past decade. The initial developments, such as regression-based and U-Net-based networks, established the foundation for deep learning in…

Image and Video Processing · Electrical Eng. & Systems 2024-11-04 Junyu Chen , Yihao Liu , Shuwen Wei , Zhangxing Bian , Shalini Subramanian , Aaron Carass , Jerry L. Prince , Yong Du

Recent advances in deep learning-based medical image registration have shown that training deep neural networks~(DNNs) does not necessarily require medical images. Previous work showed that DNNs trained on randomly generated images with…

Computer Vision and Pattern Recognition · Computer Science 2025-06-02 Junyu Chen , Shuwen Wei , Yihao Liu , Aaron Carass , Yong Du

The recent application of deep learning technologies in medical image registration has exponentially decreased the registration time and gradually increased registration accuracy when compared to their traditional counterparts. Most of the…

Image and Video Processing · Electrical Eng. & Systems 2020-02-19 Abdullah Nazib , Clinton Fookes , Olivier Salvado , Dimitri Perrin

The paper adapts the large deformation diffeomorphic metric mapping framework for image registration to the indirect setting where a template is registered against a target that is given through indirect noisy observations. The registration…

Numerical Analysis · Mathematics 2019-11-06 Chong Chen , Ozan Öktem

Deformable image registration is a critical technology in medical image analysis, with broad applications in clinical practice such as disease diagnosis, multi-modal fusion, and surgical navigation. Traditional methods often rely on…

Image and Video Processing · Electrical Eng. & Systems 2026-03-04 Zhengyong Huang , Xingwen Sun , Xuting Chang , Ning Jiang , Yao Wang , Jianfei Sun , Hongbin Han , Yao Sui