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Interpretability plays a crucial role in the application of statistical learning to estimate heterogeneous treatment effects (HTE) in complex diseases. In this study, we leverage a rule-based workflow, namely causal rule learning (CRL), to…

Machine Learning · Computer Science 2025-11-24 Ying Wu , Hanzhong Liu , Kai Ren , Shujie Ma , Xiangyu Chang

The cerebral autoregulation system (CAS), is a mechanism which aims to regulate pressure variations occurring in the cerebral circulatory system. At present, there only exist invasive methods and, in turn, they are not used to prevent…

Signal Processing · Electrical Eng. & Systems 2020-11-25 Jorge Cuevas , Claudio Henriquez , Francisco Cruz

Computer Aided Detection (CAD) is a valuable technique for precisely interpreting medical images and it has a global business opportunity of about USD 1.8 billion. The current aspects with reference to the four sub stages such as image…

Image and Video Processing · Electrical Eng. & Systems 2020-10-01 Roshan P. Mathews , Greeta Mathews

With the development of deep learning-based methods, automated classification of electrocardiograms (ECGs) has recently gained much attention. Although the effectiveness of deep neural networks has been encouraging, the lack of information…

Signal Processing · Electrical Eng. & Systems 2022-03-02 Wenrui Zhang , Xinxin Di , Guodong Wei , Shijia Geng , Zhaoji Fu , Shenda Hong

Case Based Reasoning (CBR) is an intelligent way of thinking based on experience and capitalization of already solved cases (source cases) to find a solution to a new problem (target case). Retrieval phase consists on identifying source…

Artificial Intelligence · Computer Science 2012-11-20 Ibrahim El Bitar , Fatima-Zahra Belouadha , Ounsa Roudies

Cardiovascular disease is a major threat to health and one of the primary causes of death globally. The 12-lead ECG is a cheap and commonly accessible tool to identify cardiac abnormalities. Early and accurate diagnosis will allow early…

Signal Processing · Electrical Eng. & Systems 2021-01-13 Zhaowei Zhu , Xiang Lan , Tingting Zhao , Yangming Guo , Pipin Kojodjojo , Zhuoyang Xu , Zhuo Liu , Siqi Liu , Han Wang , Xingzhi Sun , Mengling Feng

Ratio-based biomarkers (RBBs), such as the proportion of necrotic tissue within a tumor, are widely used in clinical practice to support diagnosis, prognosis, and treatment planning. These biomarkers are typically estimated from…

Computer Vision and Pattern Recognition · Computer Science 2026-04-03 Jiameng Li , Teodora Popordanoska , Aleksei Tiulpin , Sebastian G. Gruber , Frederik Maes , Matthew B. Blaschko

Cardiovascular diseases (CVDs) are responsible for a large proportion of premature deaths in low- and middle-income countries. Early CVD detection and intervention is critical in these populations, yet many existing CVD risk scores require…

Coronary artery disease (CAD) remains the leading cause of death globally, with computed tomography coronary angiography (CTCA) serving as a key diagnostic tool. However, coronary arterial analysis using CTCA, such as identifying…

Image and Video Processing · Electrical Eng. & Systems 2025-08-12 Shisheng Zhang , Ramtin Gharleghi , Sonit Singh , Daniel Moses , Dona Adikari , Arcot Sowmya , Susann Beier

Central Serous Retinopathy (CSR) or Central Serous Chorioretinopathy (CSC) is a significant disease that causes blindness and vision loss among millions of people worldwide. It transpires as a result of accumulation of watery fluids behind…

Image and Video Processing · Electrical Eng. & Systems 2021-08-27 Syed Ale Hassan , Shahzad Akbar , Amjad Rehman , Tanzila Saba , Hoshang Kolivand , Saeed Ali Bahaj

Chronic diseases such as cancer, diabetes, heart diseases, chronic kidney disease (CKD) require a drug management system that ensures a stable and robust output of the patient's condition in response to drug dosage. In the case of CKD, the…

Quantitative Methods · Quantitative Biology 2020-08-21 Affan Affan , Tamer Inanc

Coronary Artery Disease (CAD) is one of the most common forms of heart disease, which is caused by a buildup of atherosclerotic plaque (known as stenosis) in the coronary arteries, leading to insufficient supplement of blood, oxygen, and…

Computational Engineering, Finance, and Science · Computer Science 2024-09-06 Haizhou Yang , C. Alberto Figueroa , Krishna Garikipati

In today's world, a massive amount of data is available in almost every sector. This data has become an asset as we can use this enormous amount of data to find information. Mainly health care industry contains many data consisting of…

Machine Learning · Computer Science 2022-03-10 Hafsa Binte Kibria , Abdul Matin

Rare diseases are very difficult to identify among large number of other possible diagnoses. Better availability of patient data and improvement in machine learning algorithms empower us to tackle this problem computationally. In this…

Machine Learning · Computer Science 2016-09-07 Ravi Garg , Shu Dong , Sanjiv Shah , Siddhartha R Jonnalagadda

The detection of cardiovascular diseases (CVD) using machine learning techniques represents a significant advancement in medical diagnostics, aiming to enhance early detection, accuracy, and efficiency. This study explores a comparative…

Machine Learning · Computer Science 2024-05-28 Dayana K , S. Nandini , Sanjjushri Varshini R

This study presents an application of machine learning (ML) methods for detecting the presence of stenoses and aneurysms in the human arterial system. Four major forms of arterial disease -- carotid artery stenosis (CAS), subclavian artery…

Machine Learning · Computer Science 2021-08-03 Gareth Jones , Jim Parr , Perumal Nithiarasu , Sanjay Pant

Raman spectroscopy (RS) has been widely used for disease diagnosis, e.g., cardiovascular disease (CVD), owing to its efficiency and component-specific testing capabilities. A series of popular deep learning methods have recently been…

Image and Video Processing · Electrical Eng. & Systems 2023-04-20 Bo Yu , Hechang Chen , Chengyou Jia , Hongren Zhou , Lele Cong , Xiankai Li , Jianhui Zhuang , Xianling Cong

Artificial intelligence (AI) methodologies hold great promise for the rapid and accurate diagnosis of coronary artery disease (CAD) from intravascular optical coherent tomography (IVOCT) images. Numerous papers have been published…

Image and Video Processing · Electrical Eng. & Systems 2025-02-03 Xu Chen , Yuan Huang , Benn Jessney , Jason Sangha , Sophie Gu , Carola-Bibiane Schönlieb , Martin Bennett , Michael Roberts

This study addresses a critical gap in the healthcare system by developing a clinically meaningful, practical, and explainable disease surveillance system for multiple chronic diseases, utilizing routine EHR data from multiple U.S.…

Machine Learning · Computer Science 2025-01-28 Shaheer Ahmad Khan , Muhammad Usamah Shahid , Ahmad Abdullah , Ibrahim Hashmat , Muddassar Farooq

In health and social sciences, it is critically important to identify subgroups of the study population where there is notable heterogeneity of treatment effects (HTE) with respect to the population average. Decision trees have been…

Methodology · Statistics 2024-05-28 Falco J. Bargagli-Stoffi , Riccardo Cadei , Kwonsang Lee , Francesca Dominici