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The regression discontinuity (RD) design is a quasi-experimental design that estimates the causal effects of a treatment by exploiting naturally occurring treatment rules. It can be applied in any context where a particular treatment or…

Coronary artery disease (CAD) has posed a leading threat to the lives of cardiovascular disease patients worldwide for a long time. Therefore, automated diagnosis of CAD has indispensable significance in clinical medicine. However, the…

Image and Video Processing · Electrical Eng. & Systems 2021-09-28 Xinghua Ma , Gongning Luo , Wei Wang , Kuanquan Wang

Randomized controlled trials (RCTs) are the standard for evaluating the effectiveness of clinical interventions. To address the limitations of RCTs on real-world populations, we developed a methodology that uses a large observational…

Machine Learning · Computer Science 2024-10-21 Panayiotis Petousis , David Gordon , Susanne B. Nicholas , Alex A. T. Bui

Coronary stenosis is a major risk factor for ischemic heart events leading to increased mortality, and medical treatments for this condition require meticulous, labor-intensive analysis. Coronary angiography provides critical visual cues…

Image and Video Processing · Electrical Eng. & Systems 2025-08-04 Sumin Seo , In Kyu Lee , Hyun-Woo Kim , Jaesik Min , Chung-Hwan Jung

Coronary artery disease (CAD) is often treated minimally invasively with a catheter being inserted into the diseased coronary vessel. If a patient exhibits a Shepherd's Crook (SC) Right Coronary Artery (RCA) - an anatomical norm variant of…

Using machine learning in clinical practice poses hard requirements on explainability, reliability, replicability and robustness of these systems. Therefore, developing reliable software for monitoring critically ill patients requires close…

Software Engineering · Computer Science 2021-03-16 Miroslaw Staron , Helena Odenstedt Hergés , Silvana Naredi , Linda Block , Ali El-Merhi , Richard Vithal , Mikael Elam

Quantifying uncertainty of predictions has been identified as one way to develop more trustworthy artificial intelligence (AI) models beyond conventional reporting of performance metrics. When considering their role in a clinical decision…

Computer-aided diagnosis (CAD), a vibrant medical imaging research field, is expanding quickly. Because errors in medical diagnostic systems might lead to seriously misleading medical treatments, major efforts have been made in recent years…

Machine Learning · Computer Science 2023-08-04 Farzaneh Tajidini , Mohammad-Javad Kheiri

Background and Objective: Incomplete Kawasaki disease (KD) has often been misdiagnosed due to a lack of the clinical manifestations of classic KD. However, it is associated with a markedly higher prevalence of coronary artery lesions.…

Image and Video Processing · Electrical Eng. & Systems 2022-04-07 Haeyun Lee , Yongsoon Eun , Jae Youn Hwang , Lucy Youngmin Eun

The goal is to develop a novel approach for cardiac disease prediction and diagnosis using intelligent agents. Initially the symptoms are preprocessed using filter and wrapper based agents. The filter removes the missing or irrelevant…

Multiagent Systems · Computer Science 2010-09-28 Murugesan Kuttikrishnan

Heart disorder has just overtaken cancer as the world's biggest cause of mortality. Several cardiac failures, heart disease mortality, and diagnostic costs can all be reduced with early identification and treatment. Medical data is…

Machine Learning · Computer Science 2023-04-13 Md. Maidul Islam , Tanzina Nasrin Tania , Sharmin Akter , Kazi Hassan Shakib

Cardio-cerebrovascular diseases are the leading causes of mortality worldwide, whose accurate blood vessel segmentation is significant for both scientific research and clinical usage. However, segmenting cardio-cerebrovascular structures…

Image and Video Processing · Electrical Eng. & Systems 2024-04-03 Nazik Elsayed , Yousuf Babiker M. Osman , Cheng Li , Jiong Zhang , Shanshan Wang

Sepsis is a potentially life threatening inflammatory response to infection or severe tissue damage. It has a highly variable clinical course, requiring constant monitoring of the patient's state to guide the management of intravenous…

Machine Learning · Computer Science 2022-02-21 Thesath Nanayakkara , Gilles Clermont , Christopher James Langmead , David Swigon

Fractional flow reserve (FFR) is the gold standard for diagnosing coronary artery disease (CAD). FFRCT uses computational fluid dynamics (CFD) to evaluate FFR non-invasively by simulating coronary flow in geometries reconstructed from…

To decrease patient waiting time for diagnosis of the Coronary Artery Disease, automatic methods are applied to identify its severity using Coronary Computed Tomography Angiography scans or extracted Multiplanar Reconstruction (MPR) images,…

Image and Video Processing · Electrical Eng. & Systems 2020-06-16 Mariia Dobko , Bohdan Petryshak , Oles Dobosevych

Cardiac rehabilitation constitutes a structured clinical process involving multiple interdependent phases, individualized medical decisions, and the coordinated participation of diverse healthcare professionals. This sequential and adaptive…

Machine Learning · Computer Science 2025-12-25 Alexandre Cabodevila , Pedro Gamallo-Fernandez , Juan C. Vidal , Manuel Lama

A Clinical Decision Support System (CDSS) is designed to enhance clinician decision-making by combining system-generated recommendations with medical expertise. Given the high costs, intensive labor, and time-sensitive nature of medical…

Computation and Language · Computer Science 2024-10-22 Pei-Hung Chung , Shuhan He , Norawit Kijpaisalratana , Abdel-badih el Ariss , Byung-Jun Yoon

Coronary angiography continues to serve as the primary method for diagnosing coronary artery disease (CAD), which is the leading global cause of mortality. The severity of CAD is quantified by the location, degree of narrowing (stenosis),…

Image and Video Processing · Electrical Eng. & Systems 2023-10-24 Hui Lin , Tom Liu , Aggelos Katsaggelos , Adrienne Kline

Three paediatric cardiologists assessed nearly 1000 imprecise subjective conditional probabilities for a simple belief network representing congenital heart disease, and the quality of the assessments has been measured using prospective…

Artificial Intelligence · Computer Science 2013-04-08 David J. Spiegelhalter , Rodney C. Franklin , Kate Bull

Non-contrast computed tomography calcium scoring (CTCS) is a cost-effective imaging modality widely used to detect coronary artery calcifications. This study aimed to develop an advanced machine learning framework that utilizes quantitative…

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