Related papers: Virtual staining for mitosis detection in Breast H…
Breast cancer is one of the main causes of cancer death worldwide. Early diagnostics significantly increases the chances of correct treatment and survival, but this process is tedious and often leads to a disagreement between pathologists.…
For diagnosing melanoma, hematoxylin and eosin (H&E) stained tissue slides remains the gold standard. These images contain quantitative information in different magnifications. In the present study, we investigated whether deep…
Breast cancer is a highly fatal disease among cancers in women, and early detection is crucial for treatment. HER2 status, a valuable diagnostic marker based on Immunohistochemistry (IHC) staining, is instrumental in determining breast…
Early detection and prognosis of breast cancer are feasible by utilizing histopathological grading of biopsy specimens. This research is focused on detection and grading of nuclear pleomorphism in histopathological images of breast cancer.…
Traditional breast cancer image classification methods require manual extraction of features from medical images, which not only require professional medical knowledge, but also have problems such as time-consuming and labor-intensive and…
In the field of deep learning, large architectures often obtain the best performance for many tasks, but also require massive datasets. In the histological domain, tissue images are expensive to obtain and constitute sensitive medical…
Pathology is practiced by visual inspection of histochemically stained slides. Most commonly, the hematoxylin and eosin (H&E) stain is used in the diagnostic workflow and it is the gold standard for cancer diagnosis. However, in many cases,…
Immunohistochemical (IHC) staining provides crucial molecular characterization of tissue samples and plays an indispensable role in the clinical examination and diagnosis of cancers. However, compared with the commonly used Hematoxylin and…
Predicting TNM stage is the major determinant of breast cancer prognosis and treatment. The essential part of TNM stage classification is whether the cancer has metastasized to the regional lymph nodes (N-stage). Pathologic N-stage…
Histological examination is crucial for cancer diagnosis, including hematoxylin and eosin (H&E) staining for mapping morphology and immunohistochemistry (IHC) staining for revealing chemical information. Recently developed two-color…
This is the submission for mitosis detection in the context of the MIDOG 2021 challenge. It is based on the two-stage objection model Faster RCNN as well as DenseNet as a backbone for the neural network architecture. It achieves a F1-score…
Breast cancer histopathology image classification is critical for early detection and improved patient outcomes. 1 This study introduces a novel approach leveraging EfficientNetV2 models, to improve feature extraction and focus on relevant…
Hematoxylin and eosin (H&E) staining is the clinical standard for assessing tissue morphology, but it lacks molecular-level diagnostic information. In contrast, immunohistochemistry (IHC) provides crucial insights into biomarker expression,…
According to some medical imaging techniques, breast histopathology images called Hematoxylin and Eosin are considered as the gold standard for cancer diagnoses. Based on the idea of dividing the pathologic image (WSI) into multiple…
Automated digital histopathology image segmentation is an important task to help pathologists diagnose tumors and cancer subtypes. For pathological diagnosis of cancer subtypes, pathologists usually change the magnification of whole-slide…
In this paper, we propose a Computer Assisted Diagnosis (CAD) system based on a deep Convolutional Neural Network (CNN) model, to build an end-to-end learning process that classifies breast mass lesions. We investigate the impact that has…
Automated classification of histopathological whole-slide images (WSI) of breast tissue requires analysis at very high resolutions with a large contextual area. In this paper, we present context-aware stacked convolutional neural networks…
Virtual staining, or in-silico-labeling, has been proposed to computationally generate synthetic fluorescence images from label-free images by use of deep learning-based image-to-image translation networks. In most reported studies,…
Conditional generative adversarial networks (cGANs) have enabled high-fidelity computational staining and destaining of hematoxylin and eosin (H&E) in digital pathology whole-slide images (WSI). However, their ability to generalize to…
Breast cancer is the most commonly diagnosed cancer worldwide, with over two million new cases each year. During diagnostic tumour grading, pathologists manually count the number of dividing cells (mitotic figures) in biopsy or tumour…