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It has been suggested that microtubules and other cytoskeletal filaments may act as electrical transmission lines. An electrical circuit model of the microtubule is constructed incorporating features of its cylindrical structure with…

Subcellular Processes · Quantitative Biology 2010-06-28 Holly Freedman , Vahid Rezania , Avner Priel , Eric Carpenter , Sergei Y. Noskovd , Jack A. Tuszynski

In fluid transport across nanopores, there is a fundamental dissipation that arises from the connection between the pore and the macroscopic reservoirs. This entrance effect can hinder the whole transport in certain situations, for short…

Soft Condensed Matter · Physics 2015-01-08 Simon Gravelle , Laurent Joly , Christophe Ybert , Lydéric Bocquet

Ion transport through nanopores permeates through many areas of science and technology, from cell behavior to sensing and separation to catalysis and batteries. Two-dimensional materials, such as graphene, molybdenum disulfide (MoS$_2$),…

Mesoscale and Nanoscale Physics · Physics 2019-07-19 Subin Sahu , Michael Zwolak

A microscopic physical analysis of the various resistive effects involved in the electronic detection of single biomolecules in a nanopore of a MoS2 nanoribbon is presented. The analysis relies on a combined experimental-theoretical…

Mesoscale and Nanoscale Physics · Physics 2020-04-23 Mingye Xiong , Michael Graf , Nagendra Athreya , Aleksandra Radenovic , Jean-Pierre Leburton

Selectivity towards positive and negative ions in nanopores is often associated with electroosmotic flow, the control of which is pivotal in several micro-nanofluidic technologies. Selectivity is traditionally understood to be a consequence…

Fluid Dynamics · Physics 2022-04-21 Giovanni Di Muccio , Blasco Morozzo della Rocca , Mauro Chinappi

Efficient water transport through nanostructure membranes is essential for advancing filtration and desalination technologies. In this study, we investigate the flow of water through molybdenum disulfide (MoS$_{2}$) nanopores of varying…

Materials Science · Physics 2025-10-14 João Victor Lemos Vale , Lucas Cesena , Bruno H. S. Mendonça , Elizane E. de Moraes

We report Molecular Dynamics (MD) simulations of a generic hydrophobic nanopore connecting two reservoirs which are initially at different Na+ concentrations, as in a biological cell. The nanopore is impermeable to water under equilibrium…

Biological Physics · Physics 2009-11-10 J. Dzubiella , R. J. Allen , J. -P. Hansen

In this paper we report the theory describing the electro-osmotic flow in charged nanopores with constant radius and charge density driven by alternating current. We solve the ion and solution transport in unsteady conditions as described…

Chemical Physics · Physics 2018-10-17 J. Catalano , P. M. Biesheuvel

Angstrom confined solvents in two-dimensional laminates travel through interlayer spacings, gaps between adjacent sheets, and via in plane pores. Among these, experimental access to investigate the mass transport through in plane pores is…

Biological ion channels balance electrostatic and dehydration effects to yield large ion selectivities alongside high transport rates. These macromolecular systems are often interrogated through point mutations of their pore domain,…

Mesoscale and Nanoscale Physics · Physics 2019-07-19 Subin Sahu , Justin Elenewski , Christoph Rohmann , Michael Zwolak

In living organisms, information is processed in interconnected symphonies of ionic currents spiking through protein ion channels. As a result of dynamically switching their conductive states, ion channels exhibit a variety of…

Mesoscale and Nanoscale Physics · Physics 2024-01-15 Yechan Noh , Alex Smolyanitsky

Ionic transport in nanopores or nanochannels is key to many cellular processes and is now being explored as a method for DNA/polymer sequencing and detection. Although apparently simple in its scope, the study of ionic dynamics in confined…

Mesoscale and Nanoscale Physics · Physics 2013-06-13 Andrew Meyertholen , Massimiliano Di Ventra

Ion channels regulate many essential properties of biological cells, especially the membrane potential. Despite decades of efforts on artificial channels, it remains a great challenge to mimic the dipole potential-an indispensable…

Kinetic equations for the stationary state distribution function of ions moving through narrow pores are solved for a number of one-dimensional models of single ion transport. Ions move through pores of length $L$, under the action of a…

Soft Condensed Matter · Physics 2009-11-10 Jaroslaw Piasecki , Rosalind J. Allen , Jean-Pierre Hansen

Single nanopores have attracted much scientific interest due to their versatile applications. The majority of experiments have been performed with nanopores being in contact with the same electrolyte on both sides of the membrane, while…

Chemical Physics · Physics 2018-12-11 Yinghua Qiu , Zuzanna S. Siwy , Meni Wanunu

We employ molecular dynamics simulations to investigate ion and water transport driven by an electric field through quasi-two-dimensional nanoslits with a tapered geometry. Despite the absence of surface charge on the channel walls and the…

Soft Condensed Matter · Physics 2025-09-29 Tim Veenstra , Gerardo Campos-Villalobos , Giuliana Giunta , René van Roij , Marjolein Dijkstra

Extensive molecular dynamics simulations of water permeation and ion selectivity of the single-walled carbon nanotubes with the radial deformation are presented . The simulated results indicate that there is a close relationship between the…

Mesoscale and Nanoscale Physics · Physics 2012-03-01 Xu Kui , Wang Qing-Song , Tan Bin , Chen Ming-Xuan , Miao Ling , Jiang Jian-Jun

A nonlinear kinetic exclusion model is used to study osmosis and pressure driven flows through nearly single file pores such as antibiotic channels, aquaporins, zeolites and nanotubules. Two possible maxima in the steady state flux as a…

Soft Condensed Matter · Physics 2007-05-23 Tom Chou

The phase offset between surface charge modulation and geometric undulations in a corrugated nanochannel provides a tunable mechanism for rectified, diode-like ion transport under purely pressure-driven conditions: reversing the applied…

Fluid Dynamics · Physics 2026-05-15 Thomas Petersen , Pouya Golchin , Jinwoo Im , Felipe P. J. de Barros

The number of precise conductance measurements in nanopores is quickly growing. In order to clarify the dominant mechanisms at play and facilitate the characterization of such systems for which there is still no clear consensus, we propose…

Soft Condensed Matter · Physics 2018-07-25 Manoel Manghi , John Palmeri , Khadija Yazda , Francois Henn , Vincent Jourdain