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We present a Bayesian probabilistic model to estimate the brain white matter atlas from high angular resolution diffusion imaging (HARDI) data. This model incorporates a shape prior of the white matter anatomy and the likelihood of…

Computer Vision and Pattern Recognition · Computer Science 2013-10-14 Jia Du , Alvina Goh , Anqi Qiu

Longitudinal fetal brain atlas is a powerful tool for understanding and characterizing the complex process of fetus brain development. Existing fetus brain atlases are typically constructed by averaged brain images on discrete time points…

Image and Video Processing · Electrical Eng. & Systems 2022-09-15 Lixuan Chen , Jiangjie Wu , Qing Wu , Hongjiang Wei , Yuyao Zhang

Deep learning has a great potential for estimating biomarkers in diffusion weighted magnetic resonance imaging (dMRI). Atlases, on the other hand, are a unique tool for modeling the spatio-temporal variability of biomarkers. In this paper,…

Medical Physics · Physics 2022-05-09 Davood Karimi , Ali Gholipour

Understanding and predicting the progression of neurodegenerative diseases remains a major challenge in medical AI, with significant implications for early diagnosis, disease monitoring, and treatment planning. However, most available…

Computer Vision and Pattern Recognition · Computer Science 2026-04-27 Nivetha Jayakumar , Swakshar Deb , Bahram Jafrasteh , Qingyu Zhao , Miaomiao Zhang

Diffusion-weighted magnetic resonance imaging (DW-MRI) is a critical imaging method for capturing and modeling tissue microarchitecture at a millimeter scale. A common practice to model the measured DW-MRI signal is via fiber orientation…

Magnetic Resonance Imaging (MRI) of the fetal brain has become a key tool for studying brain development in vivo. Yet, its assessment remains challenging due to variability in brain maturation, imaging protocols, and uncertain estimates of…

Image and Video Processing · Electrical Eng. & Systems 2025-10-09 Johannes Tischer , Patric Kienast , Marlene Stümpflen , Gregor Kasprian , Georg Langs , Roxane Licandro

We present a method for fast biomedical image atlas construction using neural fields. Atlases are key to biomedical image analysis tasks, yet conventional and deep network estimation methods remain time-intensive. In this preliminary work,…

Image and Video Processing · Electrical Eng. & Systems 2023-11-15 Zeen Chi , Zhongxiao Cong , Clinton J. Wang , Yingcheng Liu , Esra Abaci Turk , P. Ellen Grant , S. Mazdak Abulnaga , Polina Golland , Neel Dey

Early brain development is crucial for lifelong neurodevelopmental health. However, current clinical practice offers limited knowledge of normal embryonic brain anatomy on ultrasound, despite the brain undergoing rapid changes within the…

Anatomical atlases are widely used for population studies and analysis. Conditional atlases target a specific sub-population defined via certain conditions, such as demographics or pathologies, and allow for the investigation of…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Sophie Starck , Vasiliki Sideri-Lampretsa , Bernhard Kainz , Martin J. Menten , Tamara T. Mueller , Daniel Rueckert

We propose an integrated deep-generative framework, that jointly models complementary information from resting-state functional MRI (rs-fMRI) connectivity and diffusion tensor imaging (DTI) tractography to extract predictive biomarkers of a…

Longitudinal reproducibility is an essential concern in automated medical image segmentation, yet has proven to be an elusive objective as manual brain structure tracings have shown more than 10% variability. To improve reproducibility,…

Computer Vision and Pattern Recognition · Computer Science 2017-08-30 Yuankai Huo , Susan M. Resnick , Bennett A. Landman

We propose a large deformation diffeomorphic metric mapping algorithm to align multiple b-value diffusion weighted imaging (mDWI) data, specifically acquired via hybrid diffusion imaging (HYDI), denoted as LDDMM-HYDI. We then propose a…

Computer Vision and Pattern Recognition · Computer Science 2013-09-26 Jia Du , A. Pasha Hosseinbor , Moo K. Chung , Barbara B. Bendlin , Gaurav Suryawanshi , Andrew L. Alexander , Anqi Qiu

The infant brain undergoes rapid development in the first few years after birth.Compared to cross-sectional studies, longitudinal studies can depict the trajectories of infants brain development with higher accuracy, statistical power and…

Image and Video Processing · Electrical Eng. & Systems 2024-05-20 Zihao Zhu , Tianli Tao , Yitian Tao , Haowen Deng , Xinyi Cai , Gaofeng Wu , Kaidong Wang , Haifeng Tang , Lixuan Zhu , Zhuoyang Gu , Jiawei Huang , Dinggang Shen , Han Zhang

In this paper, we propose a novel large deformation diffeomorphic registration algorithm to align high angular resolution diffusion images (HARDI) characterized by orientation distribution functions (ODFs). Our proposed algorithm seeks an…

Computer Vision and Pattern Recognition · Computer Science 2011-07-26 Jia Du , Alvina Goh , Anqi Qiu

In the realm of neuroscience, identifying distinctive patterns associated with neurological disorders via brain networks is crucial. Resting-state functional magnetic resonance imaging (fMRI) serves as a primary tool for mapping these…

Image and Video Processing · Electrical Eng. & Systems 2025-10-27 Jiaxing Xu , Mengcheng Lan , Xia Dong , Kai He , Wei Zhang , Qingtian Bian , Yiping Ke

Major depressive disorder (MDD) is a prevalent mental disorder associated with complex neurobiological changes that cannot be fully captured using a single imaging modality. The use of multimodal magnetic resonance imaging (MRI) provides a…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Nojod M. Alotaibi , Areej M. Alhothali

Segmentation and spatial alignment of ultrasound (US) imaging data acquired in the in first trimester are crucial for monitoring human embryonic growth and development throughout this crucial period of life. Current approaches are either…

Image and Video Processing · Electrical Eng. & Systems 2023-08-29 W. A. P. Bastiaansen , M. Rousian , R. P. M. Steegers-Theunissen , W. J. Niessen , A. H. J. Koning , S. Klein

Accurate longitudinal analysis of brain MRI is often hindered by evolving lesions, which bias automated neuroimaging pipelines. While deep generative models have shown promise in inpainting these lesions, most existing methods operate…

Image and Video Processing · Electrical Eng. & Systems 2026-03-09 Zahra Karimaghaloo , Dumitru Fetco , Haz-Edine Assemlal , Hassan Rivaz , Douglas L. Arnold

High angular resolution diffusion imaging (HARDI) is a type of diffusion magnetic resonance imaging (dMRI) that measures diffusion signals on a sphere in q-space. It has been widely used in data acquisition for human brain structural…

Applications · Statistics 2021-11-12 William Consagra , Arun Venkataraman , Zhengwu Zhang

Magnetic resonance diffusion tensor imaging (DTI) is a critical tool for neural disease diagnosis. However, long scan time greatly hinders the widespread clinical use of DTI. To accelerate image acquisition, a feature-enhanced joint…

Image and Video Processing · Electrical Eng. & Systems 2024-05-28 Lang Zhang , Jinling He , Dong Liang , Hairong Zheng , Yanjie Zhu
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