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The connectivity and structural integrity of the white matter of the brain is nowadays known to be implicated into a wide range of brain-related disorders. However, it was not before the advent of diffusion Magnetic Resonance Imaging (dMRI)…

Computer Vision and Pattern Recognition · Computer Science 2014-01-27 Q. Zhou , O. Michailovich , Y. Rathi

Diffusion MRI (dMRI) is a critical non-invasive technique to estimate fiber orientation distribution (FOD) for characterizing white matter integrity. Estimating FOD from single-shell low angular resolution dMRI (LAR-FOD) is limited by…

Computer Vision and Pattern Recognition · Computer Science 2025-12-19 Hao Tang , Hanyu Liu , Alessandro Perelli , Xi Chen , Chao Li

Diffusion-weighted MR imaging (DWI) is the only method we currently have to measure connections between different parts of the human brain in vivo. To elucidate the structure of these connections, algorithms for tracking bundles of axonal…

Machine Learning · Statistics 2014-12-05 Charles Zheng , Franco Pestilli , Ariel Rokem

We present MultiMorph, a fast and efficient method for constructing anatomical atlases on the fly. Atlases capture the canonical structure of a collection of images and are essential for quantifying anatomical variability across…

Computer Vision and Pattern Recognition · Computer Science 2025-04-02 S. Mazdak Abulnaga , Andrew Hoopes , Neel Dey , Malte Hoffmann , Marianne Rakic , Bruce Fischl , John Guttag , Adrian Dalca

Purpose: To propose a deep learning-based reconstruction framework for ultrafast and robust diffusion tensor imaging and fiber tractography. Methods: We propose SuperDTI to learn the nonlinear relationship between diffusion-weighted images…

Image and Video Processing · Electrical Eng. & Systems 2021-07-27 Hongyu Li , Zifei Liang , Chaoyi Zhang , Ruiying Liu , Jing Li , Weihong Zhang , Dong Liang , Bowen Shen , Xiaoliang Zhang , Yulin Ge , Jiangyang Zhang , Leslie Ying

Predicting the spatio-temporal progression of brain tumors is essential for guiding clinical decisions in neuro-oncology. We propose a hybrid mechanistic learning framework that combines a mathematical tumor growth model with a guided…

Computer Vision and Pattern Recognition · Computer Science 2025-09-12 Daria Laslo , Efthymios Georgiou , Marius George Linguraru , Andreas Rauschecker , Sabine Muller , Catherine R. Jutzeler , Sarah Bruningk

Longitudinal brain imaging data facilitate the monitoring of structural and functional alterations in individual brains across time, offering essential understanding of dynamic neurobiological mechanisms. Such data improve sensitivity for…

Applications · Statistics 2026-02-04 Zhentao Yu , Jiaqi Ding , Guorong Wu , Quefeng Li

It is important to characterize the temporal trajectories of disease-related biomarkers in order to monitor progression and identify potential points of intervention. This is especially important for neurodegenerative diseases, as…

Methodology · Statistics 2016-04-05 Murat Bilgel , Jerry L. Prince , Dean F. Wong , Susan M. Resnick , Bruno M. Jedynak

Early infancy is a rapid and dynamic neurodevelopmental period for behavior and neurocognition. Longitudinal magnetic resonance imaging (MRI) is an effective tool to investigate such a crucial stage by capturing the developmental…

Image and Video Processing · Electrical Eng. & Systems 2024-02-22 Lianghu Guo , Tianli Tao , Xinyi Cai , Zihao Zhu , Jiawei Huang , Lixuan Zhu , Zhuoyang Gu , Haifeng Tang , Rui Zhou , Siyan Han , Yan Liang , Qing Yang , Dinggang Shen , Han Zhang

Atlas building and image registration are important tasks for medical image analysis. Once one or multiple atlases from an image population have been constructed, commonly (1) images are warped into an atlas space to study intra-subject or…

Image and Video Processing · Electrical Eng. & Systems 2022-04-04 Zhipeng Ding , Marc Niethammer

Diffusion-weighted Magnetic Resonance Imaging (dMRI) is increasingly used to study the fetal brain in utero. An important computation enabled by dMRI is streamline tractography, which has unique applications such as tract-specific analysis…

Computer Vision and Pattern Recognition · Computer Science 2024-03-06 Camilo Calixto , Camilo Jaimes , Matheus D. Soldatelli , Simon K. Warfield , Ali Gholipour , Davood Karimi

Diffusion MRI (dMRI) provides unique insights into fetal brain microstructure in utero. Longitudinal and cross-sectional fetal dMRI studies can reveal crucial neurodevelopmental changes but require precise spatial alignment across scans and…

Image and Video Processing · Electrical Eng. & Systems 2025-05-13 Bo Li , Qi Zeng , Simon K. Warfield , Davood Karimi

Diffusion magnetic resonance imaging (dMRI) is pivotal for probing the microstructure of the rapidly-developing fetal brain. However, fetal motion during scans and its interaction with magnetic field inhomogeneities result in artifacts and…

Medical Physics · Physics 2025-04-07 Haykel Snoussi , Davood Karimi , Onur Afacan , Mustafa Utkur , Ali Gholipour

Probabilistic atlases provide essential spatial contextual information for image interpretation, Bayesian modeling, and algorithmic processing. Such atlases are typically constructed by grouping subjects with similar demographic…

Machine Learning · Computer Science 2018-06-07 Yuankai Huo , Katherine Swett , Susan M. Resnick , Laurie E. Cutting , Bennett A. Landman

Diffusion-weighted (DW) MRI measures the direction and scale of the local diffusion process in every voxel through its spectrum in q-space, typically acquired in one or more shells. Recent developments in micro-structure imaging and…

We propose a method to learn a distribution of shape trajectories from longitudinal data, i.e. the collection of individual objects repeatedly observed at multiple time-points. The method allows to compute an average spatiotemporal…

Computer Vision and Pattern Recognition · Computer Science 2018-06-14 Alexandre Bône , Olivier Colliot , Stanley Durrleman

Longitudinal brain MRI is essential for lifespan study, yet high attrition rates often lead to missing data, complicating analysis. Deep generative models have been explored, but most rely solely on image intensity, leading to two key…

Computer Vision and Pattern Recognition · Computer Science 2026-01-22 Tianli Tao , Ziyang Wang , Delong Yang , Han Zhang , Le Zhang

The ultrasound (US) screening of the infant hip is vital for the early diagnosis of developmental dysplasia of the hip (DDH). The US diagnosis of DDH refers to measuring alpha and beta angles that quantify hip joint development. These two…

Image and Video Processing · Electrical Eng. & Systems 2021-06-11 Xindi Hu , Limin Wang , Xin Yang , Xu Zhou , Wufeng Xue , Yan Cao , Shengfeng Liu , Yuhao Huang , Shuangping Guo , Ning Shang , Dong Ni , Ning Gu

Accurate 3D aortic construction is crucial for clinical diagnosis, preoperative planning, and computational fluid dynamics (CFD) simulations, as it enables the estimation of critical hemodynamic parameters such as blood flow velocity,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-21 Delin An , Pan Du , Jian-Xun Wang , Chaoli Wang

Diffusion MRI offers a unique probe into neural microstructure and connectivity in the developing brain. However, analysis of neonatal brain imaging data is complicated by inevitable subject motion, leading to a series of scattered slices…