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Related papers: Imaging with protons at MedAustron

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Background and purpose: In-beam Positron Emission Tomography (PET) is one of the modalities that can be used for in-vivo non-invasive treatment monitoring in proton therapy. PET distributions obtained during various treatment sessions can…

Accurate control and monitoring of the beam is essential for precise dose delivery to tumor tissues during radiotherapy. Real-time monitoring of ion beam profiles and positions improves beam control, patient safety, and treatment…

A prototype plastic scintillating fibre based beam profile monitor was tested at the Heidelberg Ion Therapy Centre / \textit{Heidelberg Ionenstrahl Therapiezentrum} (HIT) in 2016 to determine its beam property reconstruction performance and…

Instrumentation and Detectors · Physics 2018-06-27 B. D. Leverington , M. Dziewiecki , L. Renner , R. Runze

The paper discusses some 3D simulations to compute the ionizing radiation dose during laser-plasma experiments leading to the generation of accelerated protons and electrons. Also, we suggest a new method to increase the measurement…

Instrumentation and Detectors · Physics 2019-10-02 M. Ganciu , A. Chirosca , A. Groza , E. Stancu , O. Stoican , D. B. Dreghici , B. Butoi , C. Ticos , B. Mihalcea , B. Cramariuc

The purpose of this study is to determine whether organ sparing and target coverage can be simultaneously maintained for pencil beam scanning (PBS) proton therapy treatment of thoracic tumors in the presence of motion, stopping power…

When using superconducting (SC) magnets in a gantry for proton therapy, the gantry will benefit from some reduction in size and a large reduction in weight. In this contribution we show an important additional advantage of SC magnets in…

Medical Physics · Physics 2020-01-10 K. P. Nesteruk , C. Calzolaio , D. Meer , V. Rizzoglio , M. Seidel , J. M. Schippers

Uncertainties in the proton range in tissue during proton therapy limit the precision in treatment delivery. These uncertainties result in expanded treatment margins, thereby increasing radiation dose to healthy tissue. Real-time range…

Medical Physics · Physics 2018-10-17 Kristian Smeland Ytre-Hauge , Kyrre Skjerdal , John Mattingly , Ilker Meric

The differential sparing of normal tissues relative to tumor control observed at ultra-high dose rates, referred to as the FLASH effect, has recently gained considerable attention. The therapeutic advantages of FLASH radiotherapy are…

Radiotherapy is used to treat cancer patients by damaging DNA of tumor cells using ionizing radiation. Photons are the most widely used radiation type for therapy, having been put into use soon after the first discovery of X-rays in 1895.…

Optimization and Control · Mathematics 2019-11-20 Roman Levin , Aleksandr Y. Aravkin , Minsun Kim

Charged particle therapy (CPT) is an advanced modality of radiation therapy which has grown rapidly worldwide, driven by recent developments in technology and methods of delivery. To ensure safe and high quality treatments, various…

Instrumentation and Detectors · Physics 2021-11-16 J. S. L. Yap , N. J. S. Bal , A. Kacperek , J. Resta López , C. P. Welsch

Proton and carbon ion therapy is an emerging technique used for the treatment of solid cancers. The monitoring of the dose delivered during such treatments and the on-line knowledge of the Bragg peak position is still a matter of research.…

Given the sensitivity of proton therapy to anatomical variations, this cancer treatment modality is expected to benefit greatly from integration with magnetic resonance (MR) imaging. One of the obstacles hindering such an integration are…

A number of particle physics experiments are being proposed as part of the Department of Energy HEP Intensity Frontier. Many of these experiments will utilize megawatt level proton beams onto targets to form secondary beams of muons, kaons…

Accelerator Physics · Physics 2012-10-05 Victor E. Scarpine

Purpose: Currently, calculations of proton range in proton therapy patients are based on a conversion of CT Hounsfield Units of patient tissues into proton relative stopping power. Uncertainties in this conversion necessitate larger…

Purpose: VT is a life-threatening arrhythmia commonly treated with catheter ablation; however, some cases remain refractory to conventional treatment. STAR has emerged as a non-invasive option for such patients. While photon-based STAR has…

Laser-driven ion acceleration provides ultra-short, high-charge, low-emittance beams, which are desirable for a wide range of high-impact applications. Yet after decades of research, a significant increase in maximum ion energy is still…

In this work, we proposed virtual imaging simulators as an alternative approach to experimental validation of beam range uncertainty in complex patient geometry using a computational model of a human head and a photon-counting CT scanner.…

Medical Physics · Physics 2026-01-05 S. Vrbaški , G. Stanić , S. Molinelli , M. Bhattarai , E. Abadi , M. Ciocca , E. Samei

Boron Neutron Capture Therapy (BNCT) is an innovative binary form of radiation therapy with high selectivity towards cancer tissue based on the neutron capture reaction 10B(n,$\alpha$)7Li, consisting in the exposition of patients to neutron…

Photon-counting computed tomography (PCCT) marks a significant advancement over conventional energy-integrating detector (EID) CT systems. This review highlights PCCT's superior spatial and contrast resolution, reduced radiation dose, and…

Proton therapy exploits the finite range of charged particles in tissue to achieve dose distributions no photon based modality can replicate. Yet the modality reaches fewer than 1 percent of patients who might benefit a gap rooted in cost…

Medical Physics · Physics 2026-04-28 Vivek Maradia , Martin Bues