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Related papers: An insight of a needle free injector with magnetic…

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The development of needle-free drug injection systems is of great importance to global healthcare. However, in spite of its great potential and research history over many decades, these systems are not commonly used. One of the main…

Fluid Dynamics · Physics 2012-10-16 Yoshiyuki Tagawa , Nikolai Oudalov , A. El Ghalbzouri , Chao Sun , Detlef Lohse

This study compares the penetration characteristics of impact-induced jets with those of laser-induced jets, focusing on the underlying penetration mechanism rather than device performance for needle-free injection. Using an impact-induced…

A needle-free injector using a highly focused microjet has the potential to minimize the invasiveness of drug delivery. In this study, the jet penetration depth in a soft material-which is a critical parameter for practical needle-free…

Fluid Dynamics · Physics 2024-02-08 Daichi Igarashi , Kento Kimura , Nanami Endo , Yuto Yokoyama , Hiroaki Kusuno , Yoshiyuki Tagawa

Injecting with needles causes fear, pain and contamination risks. Billions of injections every year also cause environmental burden in terms of material consumption and waste. Controlled microfluidic-jet injection systems offer a…

High speed imaging was used to capture the fast dynamics of two injection methods. The first one and perhaps the oldest known, is based on solid needles and used for dermal pigmentation, or tattooing. The second, is a novel needle-free…

Applied Physics · Physics 2019-05-01 Loreto Oyarte-Gálvez , Maria Brió Pérez , David Fernández Rivas

Illuminating a water solution with a focused continuous wave laser produces a strong local heating of the liquid that leads to the nucleation of bubbles, also known as thermocavitation. During the growth of the bubble, the surrounding…

Magnetic robotics obviate the physical connections between the actuators and end effectors resulting in ultra-minimally invasive surgeries. Even though such a wireless actuation method is highly advantageous in medical applications, the…

Robotics · Computer Science 2021-07-06 Onder Erin , Xiaolong Liu , Jiawei Ge , Lamar Mair , Yotam Barnoy , Yancy Diaz-Mercado , Axel Krieger

The stability of high-speed liquid jets is crucial for applications ranging from precision printing to needle-free drug delivery, yet it is fundamentally limited by capillary-driven breakup. A common strategy to stabilize jets is to use…

In this paper, we describe the motivation, innovation, design, running example and future development of a Fault Inject Tool (FIT). This tool enables controlled causing of cloud platform issues such as resource stress and service or VM…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-07-21 Craig Sheridan , Darren Whigham , Matej Artač

Supersonic jet noise reduction is important for high speed military aircraft. Lower acoustic levels would reduce structural fatigue leading to longer lifetime of the jet aircraft. It is not solely structural aspects which are of importance,…

This paper describes a simple yet novel system for generating a highly viscous microjet. The jet is produced inside a wettable thin tube partially submerged in a liquid. The gas-liquid interface inside the tube, which is initially concave,…

Fluid Dynamics · Physics 2018-02-07 Hajime Onuki , Yuto Oi , Yoshiyuki Tagawa

In this paper we investigate the mechanical problem of piercing a soft solid body with a needle. This phenomenon is controlled by the critical condition of needle insertion. Needle insertion involves physical and geometrical nonlinearities…

Soft Condensed Matter · Physics 2024-12-16 Stefano Fregonese , Mattia Bacca

Electron Cyclotron Resonance Ion Sources are currently the most efficient ion sources among those used in facilities dedicated to nuclear physics. The need for a more flexible magnetic field and RF injection system suggested to design and…

The paper describes the production of thin, focused microjets with velocities up to 850 m/s by the rapid vaporization of a small mass of liquid in an open liquid-filled capillary. The vaporization is caused by the absorption of a low-energy…

In medicine, needles are frequently used to deliver treatments to subsurface targets or to take tissue samples from the inside of an organ. Current clinical practice is to insert needles under image guidance or haptic feedback, although…

Systems and Control · Electrical Eng. & Systems 2020-04-29 Antje Rogalla , Sascha Lehmann , Maximilian Neidhardt , Johanna Sprenger , Marcel Bengs , Alexander Schlaefer , Sibylle Schupp

Non-volatile flip-flops (NVFFs) using power gating techniques promise to overcome the soaring leakage power consumption issue with the scaling of CMOS technology. Magnetic tunnel junction (MTJ) is a good candidate for constructing the NVFF…

Emerging Technologies · Computer Science 2020-07-15 Ziyi Wang , Zhaohao Wang , Yansong Xu , Bi Wu , Weisheng Zhao

Steerable needles are capable of accurately targeting difficult-to-reach clinical sites in the body. By bending around sensitive anatomical structures, steerable needles have the potential to reduce the invasiveness of many medical…

Robotics · Computer Science 2022-11-30 Michael Bentley , Caleb Rucker , Chakravarthy Reddy , Oren Salzman , Alan Kuntz

We have developed a liquid jet injector system that can be used for hydrated sample delivery at X-ray Free Electron Laser (XFEL) sources and 3rd generation synchrotron sources. The injector is based on the Gas Dynamic Virtual Nozzle (GDVN),…

Instrumentation and Detectors · Physics 2011-05-12 U. Weierstall , R. B. Doak , J. C. H. Spence

We present a barrier method for treating frictional contact on interfaces embedded in finite elements. The barrier treatment has several attractive features, including: (i) it does not introduce any additional degrees of freedom or…

Numerical Analysis · Mathematics 2022-06-17 Yidong Zhao , Jinhyun Choo , Yupeng Jiang , Minchen Li , Chenfanfu Jiang , Kenichi Soga

We present an initial examination of a novel approach to accurately position a patient during head and neck intensity modulated radiotherapy (IMRT). Position-based visual-servoing of a radio-transparent soft robot is used to control the…

Robotics · Computer Science 2017-02-08 Olalekan Ogunmolu , Xuejun Gu , Steve Jiang , Nicholas Gans
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