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This paper presents a novel gradient-informed slicing method for functionally graded additive manufacturing (FGM) that overcomes the limitations of conventional toolpath planning approaches, which struggle to produce truly continuous…

Computational Geometry · Computer Science 2025-08-22 Charles Wade , Devon Beck , Robert MacCurdy

Tissue Engineering concerns the three-dimensional cell growth so that bio-artificial tissues could be created and used for transplantation. The recently expressed concerns from the Tissue Engineering research community for a re-direction of…

Tissues and Organs · Quantitative Biology 2008-01-23 Veronica Saravia

Cell-free translational strategies are needed to accelerate the repair of mineralised tissues, particularly large bone defects, using minimally invasive approaches. Regenerative bone scaffolds should ideally mimic aspects of the tissue's…

Tissues and Organs · Quantitative Biology 2021-01-06 Robabeh Gharaei , Giuseppe Tronci , Parikshit Goswami , Robert P. Wynn Davies , Jennifer Kirkham , Stephen J. Russell

Laser Additive Manufacturing (LAM) presents unparalleled opportunities for fabricating complex, high-performance structures and components with unique material properties. Despite these advancements, achieving consistent part quality and…

Signal Processing · Electrical Eng. & Systems 2024-04-24 Lequn Chen , Guijun Bi , Xiling Yao , Jinlong Su , Chaolin Tan , Wenhe Feng , Michalis Benakis , Youxiang Chew , Seung Ki Moon

Antimicrobial peptides (AMPs) have exhibited unprecedented potential as biomaterials in combating multidrug-resistant bacteria. Despite the increasing adoption of artificial intelligence for novel AMP design, challenges pertaining to…

Quantitative Methods · Quantitative Biology 2024-05-03 Li Wang , Yiping Li , Xiangzheng Fu , Xiucai Ye , Junfeng Shi , Gary G. Yen , Xiangxiang Zeng

Composite joints with high-performance close to the parent materials of aluminum matrix composites were fabricated by a new joining technology assisted by ultrasonic vibration. We found both the microstructure and the mechanical performance…

Materials Science · Physics 2017-07-05 Xuesong Leng , Wei Yang , Jiaheng Zhang , Xing Ma , Weiwei Zhao , Jiuchun Yan

3D porous scaffolds based on agarose and nanocrystalline apatite, two structural components that act as a temporary mineralized extracellular matrix, were prepared by the GELPOR3D method. This shaping technology allows the introduction of…

Tissues and Organs · Quantitative Biology 2021-03-18 Juan L. Paris , Nuria Lafuente-Gomez , M. Victoria Cabanas , Jesus Roman , Juan Pena , Maria Vallet-Regi

We present a novel computational paradigm for process design in manufacturing processes that incorporates simulation responses to optimize manufacturing process parameters in high-dimensional temporal and spatial design spaces. We developed…

Computational Engineering, Finance, and Science · Computer Science 2021-07-26 Mojtaba Mozaffar , Jian Cao

During the last decade, additive manufacturing has become increasingly popular for rapid prototyping, but has remained relatively marginal beyond the scope of prototyping when it comes to applications with tight tolerance specifications,…

Logic in Computer Science · Computer Science 2017-05-16 Kévin Garanger , Eric Feron , Pierre-Loïc Garoche , Julian J. Rimoli , John D. Berrigan , Martha Grover , Kerianne Hobbs

A contemporary procedure to grow artificial tissue is to seed cells onto a porous biomaterial scaffold and culture it within a perfusion bioreactor to facilitate the transport of nutrients to growing cells. Typical models of cell growth for…

Tissues and Organs · Quantitative Biology 2018-05-01 Andrew L. Krause , Dmitry Beliaev , Robert A. Van Gorder , Sarah L. Waters

Thiol self assembled monolayers (SAMs) are widely used in many nano- and bio-technology applications. We report a new approach to create and characterize a thiol SAMs micropattern with alternating charges on a flat goldcoated substrate…

Biological Physics · Physics 2017-04-28 Brad Moores , Janet Simons , S Xu , Zoya Leonenko

Surface modification of polymeric biomaterials using plasma has emerged as an effective strategy to optimize the cell-material interface without compromising the structural properties of the material. This work presents a critical review of…

Plasma Physics · Physics 2025-04-08 Jairo Rondøn , Angel Gonzalez-Lizardo

To respond to the increasing need for bone repair strategies, various types of biomaterials have been developed. Among those, calcium phosphate ceramics (CPCs) are promising since they possess a chemical composition similar to that of…

Materials Science · Physics 2021-03-03 Peifang Dee , Ha Young You , Swee-Hin Teoh , Hortense Le Ferrand

Additive manufacturing (AM) of metallic components promises many advantages over conventional manufacturing processes through high design flexibility across multiple length scales and precision coupled with an astonishing combination of…

The increasing demand for bone grafts due to the aging population has opened new opportunities for the manufacture of porous ceramics to assist in bone reconstruction. In our study, we investigate a new, promising method to manufacture…

Soft Condensed Matter · Physics 2024-12-04 Souhaila Nider , Femke De Ceulaer , Berfu Göksel , Annabel Braem , Erin Koos

This work investigates the manufacturing of complex shapes parts with wire arc additive manufacturing (WAAM). In order to guarantee the integrity and quality of each deposited layer that composes the final piece, the deposition process is…

Robotics · Computer Science 2026-02-24 Fernando Coutinho , Nicolas Lizarralde , Fernando Lizarralde

Additive manufacturing and 3D printing in particular have the potential to revolutionize existing fabrication processes where objects with complex structures and shapes can be built with multifunctional material systems. For electrochemical…

Applied Physics · Physics 2019-12-11 Umair Gulzar , Colm Glynn , Colm O'Dwyer

Natural ceramic composites present complex microstructures that lead to tortuous crack paths and confer them high toughness. Current microreinforced composites do not yet reach the same level of complexity in their microstructures,…

Materials Science · Physics 2022-01-14 Xin Ying Chan , Clarence Chua , Sharlene Tan , Hortense Le Ferrand

The paper studies the possibility of using artificial neural networks (ANN) to determine certain mechanical properties of a new composite material. This new material is obtained by a mixture of hemp and polypropylene fibres. The material…

Machine Learning · Computer Science 2019-01-30 Emilia Ciupan , Mihai Ciupan , Daniela-Corina Jucan

Novel quantum technologies and devices place unprecedented demands on the performance of experimental components, while their widespread deployment beyond the laboratory necessitates increased robustness and fast, affordable production. We…

Atomic Physics · Physics 2021-08-18 S H Madkhaly , L A Coles , C Morley , C D Colquhoun , T M Fromhold , N Cooper , L Hackermüller
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