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Diffusion-weighted magnetic resonance imaging (DW-MRI) is a critical imaging method for capturing and modeling tissue microarchitecture at a millimeter scale. A common practice to model the measured DW-MRI signal is via fiber orientation…

Diffusion-weighted (DW) MRI measures the direction and scale of the local diffusion process in every voxel through its spectrum in q-space, typically acquired in one or more shells. Recent developments in micro-structure imaging and…

Confocal histology provides an opportunity to establish intra-voxel fiber orientation distributions that can be used to quantitatively assess the biological relevance of diffusion weighted MRI models, e.g., constrained spherical…

Diffusion-weighted magnetic resonance imaging (DW-MRI) allows for non-invasive imaging of the local fiber architecture of the human brain at a millimetric scale. Multiple classical approaches have been proposed to detect both single (e.g.,…

Diffusion-weighted magnetic resonance imaging (DW-MRI) can be used to characterise the microstructure of the nervous tissue, e.g. to delineate brain white matter connections in a non-invasive manner via fibre tracking. Magnetic Resonance…

We present a rotation-equivariant unsupervised learning framework for the sparse deconvolution of non-negative scalar fields defined on the unit sphere. Spherical signals with multiple peaks naturally arise in Diffusion MRI (dMRI), where…

Image and Video Processing · Electrical Eng. & Systems 2021-02-19 Axel Elaldi , Neel Dey , Heejong Kim , Guido Gerig

Accurate local fiber orientation distribution (FOD) modeling based on diffusion magnetic resonance imaging (dMRI) capable of resolving complex fiber configurations benefits from specific acquisition protocols that sample a high number of…

Image and Video Processing · Electrical Eng. & Systems 2020-12-18 Oeslle Lucena , Sjoerd B. Vos , Vejay Vakharia , John Duncan , Keyoumars Ashkan , Rachel Sparks , Sebastien Ourselin

Diffusion Magnetic Resonance Imaging (dMRI) is a non-invasive method for depicting brain microstructure in vivo. Fiber orientation distributions (FODs) are mathematical representations extensively used to map white matter fiber…

Image and Video Processing · Electrical Eng. & Systems 2025-04-22 Rizhong Lin , Hamza Kebiri , Ali Gholipour , Yufei Chen , Jean-Philippe Thiran , Davood Karimi , Meritxell Bach Cuadra

We propose a new method, Patch-CNN, for diffusion tensor (DT) estimation from only six-direction diffusion weighted images (DWI). Deep learning-based methods have been recently proposed for dMRI parameter estimation, using either voxel-wise…

Computer Vision and Pattern Recognition · Computer Science 2023-07-06 Tobias Goodwin-Allcock , Ting Gong , Robert Gray , Parashkev Nachev , Hui Zhang

Intra-voxel models of the diffusion signal are essential for interpreting organization of the tissue environment at micrometer level with data at millimeter resolution. Recent advances in data driven methods have enabled direct compari-son…

We present a method for estimating intravoxel parameters from a DW-MRI based on deep learning techniques. We show that neural networks (DNNs) have the potential to extract information from diffusion-weighted signals to reconstruct cerebral…

Image and Video Processing · Electrical Eng. & Systems 2022-01-02 Hanna Ehrlich , Mariano Rivera

Diffusion MRI (dMRI) plays a crucial role in studying brain white matter connectivity. Cortical surface reconstruction (CSR), including the inner whiter matter (WM) and outer pial surfaces, is one of the key tasks in dMRI analyses such as…

Tissues and Organs · Quantitative Biology 2025-03-07 Chengjin Li , Yuqian Chen , Nir A. Sochen , Wei Zhang , Carl-Fredrik Westin , Rathi Yogesh , Lauren J. O'Donnell , Ofer Pasternak , Fan Zhang

Constrained Spherical Deconvolution (CSD) is widely used to estimate the white matter fiber orientation distribution (FOD) from diffusion MRI data. Its angular resolution depends on the maximum spherical harmonic order ($l_{max}$): low…

This paper demonstrates spherical convolutional neural networks (S-CNN) offer distinct advantages over conventional fully-connected networks (FCN) at estimating scalar parameters of tissue microstructure from diffusion MRI (dMRI). Such…

Image and Video Processing · Electrical Eng. & Systems 2022-08-17 Tobias Goodwin-Allcock , Jason McEwen , Robert Gray , Parashkev Nachev , Hui Zhang

We present Roto-Translation Equivariant Spherical Deconvolution (RT-ESD), an $E(3)\times SO(3)$ equivariant framework for sparse deconvolution of volumes where each voxel contains a spherical signal. Such 6D data naturally arises in…

Image and Video Processing · Electrical Eng. & Systems 2023-04-14 Axel Elaldi , Guido Gerig , Neel Dey

Identifying and characterizing brain fiber bundles can help to understand many diseases and conditions. An important step in this process is the estimation of fiber orientations using Diffusion-Weighted Magnetic Resonance Imaging (DW-MRI).…

Image and Video Processing · Electrical Eng. & Systems 2024-02-20 Mateus Oliveira da Silva , Caio Pinheiro Santana , Diedre Santos do Carmo , Letícia Rittner

Each voxel in a diffusion MRI (dMRI) image contains a spherical signal corresponding to the direction and strength of water diffusion in the brain. This paper advances the analysis of such spatio-spherical data by developing convolutional…

Image and Video Processing · Electrical Eng. & Systems 2024-11-19 Axel Elaldi , Guido Gerig , Neel Dey

Segmentation of white matter lesions and deep grey matter structures is an important task in the quantification of magnetic resonance imaging in multiple sclerosis. In this paper we explore segmentation solutions based on convolutional…

Diffusion MRI (dMRI) is the primary imaging modality used to study brain microstructure in vivo. Reliable and computationally efficient parameter inference for common dMRI biophysical models is a challenging inverse problem, due to factors…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 William Consagra , Lipeng Ning , Yogesh Rathi

T2-weighted magnetic resonance imaging (MRI) and diffusion-weighted imaging (DWI) are essential components for cervical cancer diagnosis. However, combining these channels for training deep learning models are challenging due to…

Image and Video Processing · Electrical Eng. & Systems 2023-06-21 Reza Kalantar , Sebastian Curcean , Jessica M Winfield , Gigin Lin , Christina Messiou , Matthew D Blackledge , Dow-Mu Koh
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