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Related papers: Ultrasensitive THz Biosensor for PCR-free cDNA det…

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We experimentally show that indirect light-induced electron transitions could lead to THz detection on standard CCD and CMOS sensors, introducing this well-established technological concept to the THz range. Unlike its optical counterpart,…

Optics · Physics 2015-04-15 Mostafa Shalaby , Carlo Vicario , Christoph P. Hauri

Efficient capture and detection of minute amount of deoxyribonucleic acid (DNA) molecules are pivotal for an array of modern gene technologies which are widely utilized in medical, forensic and defense applications, including DNA…

Biological Physics · Physics 2018-11-19 Jianhe Guo , Kwanoh Kim , Peter Vandeventer , Donglei , Fan

In this paper, we present a new approach for robust reading of identification and sensor data from chipless RFID sensor tags. For the first time, Machine Learning (ML) and Deep Learning (DL) regression modelling techniques are applied to a…

Signal Processing · Electrical Eng. & Systems 2023-08-29 Nadeem Rather , Roy B. V. B. Simorangkir , John L. Buckley , Brendan O'Flynn , Salvatore Tedesco

We present a method for the measurements of the tetrahertz (THz) resonance response of DNA oligonucleotides deposited on a silicon nanosandwich (SNS). It is shown that the SNS device can be used to generate a THz resonance response within…

Applied Physics · Physics 2020-12-03 K. B. Taranets , M. A. Fomin , L. E. Klyachkin , A. M. Malyarenko , N. T. Bagraev , A. L. Chernev

Terahertz (THz) technology is promising in several applications such as imaging, spectroscopy and communications. Among several methods in the generation and detection of THz waves, a THz time domain system (TDS) that is developed using…

Terahertz (THz) spectroscopy holds transformative potential for non-invasive sensing, yet characterizing individual nanoparticles in complex biological environments remains challenging due to the far-field diffraction limit. While…

Applied Physics · Physics 2026-02-06 Ricardo Martin Abraham-Ekeroth , Dani Torrent

Nonlinear terahertz (THz) spectroscopy relies on the interaction of matter with few-cycle THz pulses of electric field amplitudes up to megavolts/centimeter (MV/cm). In condensed-phase molecular systems, both resonant interactions with…

Chemical Physics · Physics 2021-12-08 Klaus Reimann , Michael Woerner , Thomas Elsaesser

Spectacular advances in heterodyne astronomy with both the Herschel Space Observatory and Stratospheric Observatory for Far Infrared Astronomy (SOFIA) have been largely due to breakthroughs in detector technology. In order to exploit the…

Mesoscale and Nanoscale Physics · Physics 2019-10-01 S. Lara-Avila , A. Danilov , D. Golubev , H. He , K. H. Kim , R. Yakimova , F. Lombardi , T. Bauch , S. Cherednichenko , S. Kubatkin

We demonstrate a method to double the collection efficiency in Laser Tweezers Raman Spectroscopy (LTRS) by collecting both the forward and back-scattered light in a single-shot multitrack measurement. Our method can collect signals at…

Optics · Physics 2021-06-09 Tobias Dahlberg , Magnus Andersson

Mass-sensing biosensor arrays for protein detection require no fluorophores or enzyme labels. However, few mass biosensor protein arrays have demonstrated successful application in high background samples, such as serum. In this paper, we…

Biological Physics · Physics 2009-07-27 Xuefeng Wang , Ming Zhao , David D Nolte , Timothy L Ratliff

The common terahertz time-domain spectroscopy (THz-TDS) based on photoconductive antenna (PCA) needs two separate PCA chips. One PCA works as an emitter, and the other works as a receiver. For a reflection-type measurement, the technique…

Optics · Physics 2013-12-17 Jitao Zhang

DNA surface-hybridization biosensors utilize the selective hybridization of target sequences in solution to surface-immobilized probes. In this process, the target is usually assumed to be in excess, so that its concentration does not…

Biomolecules · Quantitative Biology 2019-09-27 Stefanos K. Nomidis , Michal Szymonik , Tom Venken , Enrico Carlon , Jef Hooyberghs

Semiconductor nanowire field-effect transistors represent a promising platform for the development of room-temperature (RT) terahertz (THz) frequency light detectors due to the strong nonlinearity of their transfer characteristics and their…

Continuous Wave (CW) Terahertz spectroscopy enabled by photomixing is a promising high precision spectroscopic tool for the examination of a wide variety of samples including biological, chemical, and solid state. However, often it would be…

Optics · Physics 2022-12-06 James Seddon , Chris Graham , Marie Georgiades , Cyril Renaud , Alwyn Seeds

Metamaterial perfect absorbers from microwaves to optical part of the electromagnetic spectrum has been intensely studied for its ability to absorb electromagnetic radiation. Perfect absorption of light by metamaterials have opened up new…

Optics · Physics 2014-08-19 Longqing Cong , Ranjan Singh

A graphene channel field-effect biosensor is demonstrated for detecting the binding of double-stranded DNA and poly-l-lysine. Sensors consist of CVD graphene transferred using a clean, etchant-free transfer method. The presence of DNA and…

Mesoscale and Nanoscale Physics · Physics 2016-01-07 Aniket Kakatkar , T. S. Abhilash , Roberto De Alba , Jeevak M Parpia , Harold G Craighead

Refractometric biosensing is a vital label-free tool for the real time detection and interaction analysis of biological and chemical substances. Nanophotonic platforms like Surface Plasmon Resonance (SPR) have played a critical role in…

This paper describes a THz transmission spectrometer for the spectral range of 2-65 cm^-1 (100 GHz to 2 THz) with a spectral resolution of at least 1.8 cm^-1 (50 GHz) where the source, sample, and detector are all fully contained in a…

Instrumentation and Detectors · Physics 2009-11-07 P. J. Burke , J. P. Eisenstein , L. N. Pfeiffer , K. W. West

Terahertz time-domain spectroscopy (THz-TDS) employs sub-picosecond pulses to probe dielectric properties of materials giving as a result a 3-dimensional hyperspectral data cube. The spatial resolution of THz images is primarily limited by…

Genomics biobanks are information treasure troves with thousands of phenotypes (e.g., diseases, traits) and millions of single nucleotide polymorphisms (SNPs). The development of methodologies that provide reproducible discoveries is…

Methodology · Statistics 2024-10-08 Jasin Machkour , Michael Muma , Daniel P. Palomar
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