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With high-throughput biotechnologies generating unprecedented quantities of data, researchers are faced with the challenge of locating and comparing an exponentially growing number of programs and websites dedicated to computational…

Individuals and organizations cope with an always-growing amount of data, which is heterogeneous in its contents and formats. An adequate data management process yielding data quality and control over its lifecycle is a prerequisite to…

Scientists strive to make their datasets available in open repositories, with the goal that they be findable, accessible, interoperable, and reusable (FAIR). Although it is hard for most investigators to remember all the guiding principles…

Digital Libraries · Computer Science 2025-07-31 Mark A. Musen , Martin J. O'Connor , Josef Hardi , Marcos Martinez-Romero

Synthetic data is widely used in healthcare to create datasets that are similar to original data but without the privacy concerns. Generating and evaluating synthetic data across privacy, utility and fairness is crucial for facilitating…

Increasingly, artificial intelligence (AI) and machine learning (ML) are used in eScience applications [9]. While these approaches have great potential, the literature has shown that ML-based approaches frequently suffer from results that…

Machine Learning · Computer Science 2024-07-03 Zhiwei Li , Carl Kesselman , Mike D'Arch , Michael Pazzani , Benjamin Yizing Xu

From a data perspective, the materials mechanics field is characterized by sparsity of available data, mainly due to the strong microstructure-sensitivity of properties like strength, fracture toughness, and fatigue limit. This requires…

Computational Physics · Physics 2024-11-19 Ronak Shoghi , Alexander Hartmaier

Driven by the recent advances in smart, miniaturized, and mass produced sensors, networked systems, and high-speed data communication and computing, the ability to collect and process larger volumes of higher veracity real-time data from a…

Other Computer Science · Computer Science 2018-09-03 Chun-An Chou , Xiaoning Jin , Amy Mueller , Sarah Ostadabbas

In this paper, we present BIMS (Biomedical Information Management System). BIMS is a software architecture designed to provide a flexible computational framework to manage the information needs of a wide range of biomedical research…

Software Engineering · Computer Science 2013-03-26 Oscar Mora , Jesús Bisbal

High Performance Computing (HPC) centers provide resources to users who require greater scale to "get science done". They deploy infrastructure with singular hardware architectures, cutting-edge software environments, and stricter security…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-07-22 Sean R. Wilkinson , Patrick Widener

While automated experiments and high-throughput methods are becoming more mainstream in the age of data, empowering individual researchers to capture, collate, and contextualize their data faster and more reproducibly still remains a…

Computers and Society · Computer Science 2020-07-30 Ha-Kyung Kwon , Chirranjeevi Balaji Gopal , Jared Kirschner , Santiago Caicedo , Brian D. Storey

With the increasingly digital nature of biomedical data and as the complexity of analyses in medical research increases, the need for accurate information capture, traceability and accessibility has become crucial to medical researchers in…

Software Engineering · Computer Science 2014-02-25 R. McClatchey , A. Branson , A. Anjum , P. Bloodsworth , I. Habib , K. Munir , J. Shamdasani , K. Soomro , the neuGRID Consortium

Currently, there are many difficulties regarding the interoperability of medical data and related population data sources. These complications get in the way of the generation of high-quality data sets at city, region and national levels.…

Computers and Society · Computer Science 2023-10-13 Anna Andreychenko , Viktoriia Korzhuk , Stanislav Kondratenko , Polina Cheraneva

Making data compliant with the FAIR Data principles (Findable, Accessible, Interoperable, Reusable) is still a challenge for many researchers, who are not sure which criteria should be met first and how. Illustrated from experimental data…

Other Quantitative Biology · Quantitative Biology 2020-12-18 Daniel Jacob , Romain David , Sophie Aubin , Yves Gibon

The majority of contemporary mobile devices and personal computers are based on heterogeneous computing platforms that consist of a number of CPU cores and one or more Graphics Processing Units (GPUs). Despite the high volume of these…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-02-20 Jani Boutellier , Jiahao Wu , Heikki Huttunen , Shuvra S. Bhattacharyya

Scientific data governance should prioritize maximizing the utility of data throughout the research lifecycle. Research software systems that enable analysis reproducibility inform data governance policies and assist administrators in…

Neuroscience research has expanded dramatically over the past 30 years by advancing standardization and tool development to support rigor and transparency. Consequently, the complexity of the data pipeline has also increased, hindering…

Life-science experimental methods generate vast and ever-increasing volumes of data, which provide highly valuable research resources. However, management of these data is nontrivial and applicable software solutions are currently subject…

Summary: Data management in clinical metabolomics studies is often inadequate. To improve this situation we created LabPipe to provide a guided, customisable approach to study-specific sample collection. It is driven through a local client…

The broad sharing of research data is widely viewed as of critical importance for the speed, quality, accessibility, and integrity of science. Despite increasing efforts to encourage data sharing, both the quality of shared data, and the…

Digital Libraries · Computer Science 2022-08-30 William Dempsey , Ian Foster , Scott Fraser , Carl Kesselman

The cost of conducting multi-site clinical trials has significantly increased over time, with site monitoring, data management, and amendments being key drivers. Clinical trial data management approaches typically rely on a central…

Databases · Computer Science 2019-02-12 Olivia Choudhury , Noor Fairoza , Issa Sylla , Amar Das