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In low-resource settings, prevalence mapping relies on empirical prevalence data from a finite, often spatially sparse, set of surveys of communities within the region of interest, possibly supplemented by remotely sensed images that can…

Applications · Statistics 2015-05-27 Peter J. Diggle , Emanuele Giorgi

Spatial microeconometric studies typically suffer from various forms of inaccuracies that are not present when dealing with the classical regional spatial econometrics models. Among those, missing data, locational errors, sampling without a…

Methodology · Statistics 2019-04-04 Giuseppe Arbia , Paolo Berta , Carrie B. Dolan

Time elapsed till an event of interest is often modeled using the survival analysis methodology, which estimates a survival score based on the input features. There is a resurgence of interest in developing more accurate prediction models…

Machine Learning · Computer Science 2024-07-23 Navid Seidi , Ardhendu Tripathy , Sajal K. Das

Understanding the complex nature of spatial information is crucial for problem solving in social and environmental sciences. This study investigates how the underlying patterns of spatial data can significantly influence the outcomes of…

Physics and Society · Physics 2024-09-17 Peng Luo , Yongze Song , Wenwen Li , Liqiu Meng

There are well-established methods for identifying the causal effect of a time-varying treatment applied at discrete time points. However, in the real world, many treatments are continuous or have a finer time scale than the one used for…

Methodology · Statistics 2023-06-16 Jinghao Sun , Forrest W. Crawford

This paper investigates the problem of adjusting for spatial effects in genomic prediction. Despite being seldomly considered in genomic prediction, spatial effects often affect phenotypic measurements of plants. We consider a Gaussian…

Applications · Statistics 2020-06-09 Xiaojun Mao , Somak Dutta , Raymond K. W. Wong , Dan Nettleton

Epidemiologists commonly use regional aggregates of health outcomes to map mortality or incidence rates and identify geographic disparities. However, to detect health disparities across regions, it is necessary to identify "difference…

Methodology · Statistics 2025-05-14 Luca Aiello , Sudipto Banerjee

The characteristics and determinants of health and disease are often organised in space, reflecting our spatially extended nature. Understanding the influence of such factors requires models capable of capturing spatial relations. Though a…

We investigate spatial confounding in the presence of multivariate disease dependence. In the "analysis model perspective" of spatial confounding, adding a spatially dependent random effect can lead to significant variance inflation of the…

Methodology · Statistics 2026-02-13 Kyle Lin Wu , Sudipto Banerjee

In many clinical trials, outcomes of interest include binary-valued endpoints. It is not uncommon that a binary-valued outcome is dichotomized from a continuous outcome at a threshold of clinical interest. To reach the objective, common…

Applications · Statistics 2021-08-05 Chenchen Ma , Xin Shen , Yongming Qu , Yu Du

Infectious diseases remain one of the major causes of human mortality and suffering. Mathematical models have been established as an important tool for capturing the features that drive the spread of the disease, predicting the progression…

Spatial interference and spatial confounding are two major issues inhibiting precise causal estimates when dealing with observational spatial data. Moreover, the definition and interpretation of spatial confounding remain arguable in the…

Methodology · Statistics 2026-02-04 Isqeel Ogunsola , Olatunji Johnson

In order to conduct analyses of networked systems where connections between individuals take on a range of values - counts, continuous strengths or ordinal rankings - a common technique is to dichotomize the data according to their…

Applications · Statistics 2015-03-17 Andrew C. Thomas , Joseph K. Blitzstein

Residuals in regression models are often spatially correlated. Prominent examples include studies in environmental epidemiology to understand the chronic health effects of pollutants. I consider the effects of residual spatial structure on…

Methodology · Statistics 2010-11-05 Christopher J. Paciorek

In this paper we set out general principles and develop geostatistical methods for the analysis of data from spatio-temporally referenced prevalence surveys. Our objective is to provide a tutorial guide that can be used in order to identify…

Methodology · Statistics 2018-02-20 Emanuele Giorgi , Peter J. Diggle , Robert W. Snow , Abdisalan M. Noor

Empirical research in economics often examines the behavior of agents located in a geographic space. In such cases, statistical inference is complicated by the interdependence of economic outcomes across locations. A common approach to…

Econometrics · Economics 2025-04-21 Stefano DellaVigna , Guido Imbens , Woojin Kim , David M. Ritzwoller

Mendelian randomization uses genetic variants to make causal inferences about a modifiable exposure. Subject to a genetic variant satisfying the instrumental variable assumptions, an association between the variant and outcome implies a…

Methodology · Statistics 2018-04-17 Stephen Burgess , Jeremy A Labrecque

Multiple diagnostic tests are often used due to limited resources or because they provide complementary information on the epidemiology of a disease under investigation. Existing statistical methods to combine prevalence data from multiple…

Applications · Statistics 2018-08-10 Benjamin Amoah , Emanuele Giorgi , Peter Diggle

Disaggregation regression has become an important tool in spatial disease mapping for making fine-scale predictions of disease risk from aggregated response data. By including high resolution covariate information and modelling the data…

Applications · Statistics 2020-05-08 Rohan Arambepola , Tim C D Lucas , Anita K Nandi , Peter W Gething , Ewan Cameron

Spaces with locally varying scale of measurement, like multidimensional structures with differently scaled dimensions, are pretty common in statistics and machine learning. Nevertheless, it is still understood as an open question how to…

Machine Learning · Statistics 2024-03-05 Christoph Jansen , Georg Schollmeyer , Hannah Blocher , Julian Rodemann , Thomas Augustin
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