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Multiple Instance Learning (MIL) is a cornerstone approach in computational pathology (CPath) for generating clinically meaningful slide-level embeddings from gigapixel tissue images. However, MIL often struggles with small, weakly…

Computer Vision and Pattern Recognition · Computer Science 2025-06-12 Daniel Shao , Richard J. Chen , Andrew H. Song , Joel Runevic , Ming Y. Lu , Tong Ding , Faisal Mahmood

We investigate infectious disease spreading on scale-free networks using a heterogeneous mean-field approach applied to the susceptible-infected-susceptible model, incorporating a mitigation factor. Individual heterogeneity is incorporated…

Statistical Mechanics · Physics 2026-05-12 João Gabriel Simões Delboni , M. O. Hase

Most of the common used models of epidemic spreading allow contaminating many neighbors of a particular node in the network. They are usually analyzed by differential equations on probability vectors. We propose a model of epidemic…

Physics and Society · Physics 2018-02-14 Wojciech Ganczarek

Epidemic forecasting is the key to effective control of epidemic transmission and helps the world mitigate the crisis that threatens public health. To better understand the transmission and evolution of epidemics, we propose EpiGNN, a graph…

Quantitative Methods · Quantitative Biology 2022-08-25 Feng Xie , Zhong Zhang , Liang Li , Bin Zhou , Yusong Tan

The study of how diseases spread has greatly benefited from advances in network modeling. Recently, a class of networks known as multilayer graphs has been shown to describe more accurately many real systems, making it possible to address…

Physics and Society · Physics 2019-04-16 Xiangrong Wang , Alberto Aleta , Dan Lu , Yamir Moreno

Hundreds of millions of people worldwide are affected by viral infections each year, and yet, several of them neither have vaccines nor effective treatment during and post-infection. This challenge has been highlighted by the COVID-19…

We propose a model for epidemic spreading on a finite complex network with a restriction to at most one contamination per time step. Because of a highly discrete character of the process, the analysis cannot use the continous approximation,…

Physics and Society · Physics 2013-07-23 Wojciech Ganczarek

The transmission dynamics of an epidemic are rarely homogeneous. Super-spreading events and super-spreading individuals are two types of heterogeneous transmissibility. Inference of super-spreading is commonly carried out on secondary case…

Quantitative Methods · Quantitative Biology 2025-01-23 Hannah Craddock , Simon EF Spencer , Xavier Didelot

An approach is developed for analyzing computer networks to identify systems and accounts that are at particular risk of compromise by an adversary seeking to move laterally through the network via authentication. The dynamics of the…

Cryptography and Security · Computer Science 2019-08-27 Brian A. Powell

Despite being similar in structure, functioning, and size viral pathogens enjoy very different mostly well-defined ways of life. They occupy their hosts for a few days (influenza), for a few weeks (measles), or even lifelong (HCV), which…

Populations and Evolution · Quantitative Biology 2020-05-01 Alexander Lange

Most theoretical tools available for the analysis of spreading processes over networks assume exponentially distributed transmission and recovery times. In practice, the empirical distribution of transmission times for many real spreading…

Social and Information Networks · Computer Science 2016-11-04 Masaki Ogura , Victor M. Preciado

The study proposes a modeling framework for investigating the disease dynamics with adaptive human behavior during a disease outbreak, considering the impacts of both local observations and global information. One important application…

Physics and Society · Physics 2020-08-26 Xinwu Qian , Jiawei Xue , Satish V. Ukkusuri

Understanding the process by which a contagion disseminates throughout a network is of great importance in many real world applications. The required sophistication of the inference approach depends on the type of information we want to…

Social and Information Networks · Computer Science 2017-05-26 Shohreh Shaghaghian , Mark Coates

Discrete and Continuous Dynamics is the first in a series of articles on Network Models for Epidemiology. This project began in the Fall quarter of 2014 in my continuous modeling course. Since then, it has taken off and turned into a series…

Populations and Evolution · Quantitative Biology 2015-11-04 Edward Rusu

Pattern analysis of tandem repeats in gene is an indispensable computational approach to the understanding of the gene expression and pathogenesis of diseases. This research applied a computational motif model and database techniques to…

Genomics · Quantitative Biology 2013-02-11 Sim-Hui Tee

Artificial intelligence (AI) has brought tremendous impacts on biomedical sciences from academic researches to clinical applications, such as in biomarkers' detection and diagnosis, optimization of treatment, and identification of new…

Quantitative Methods · Quantitative Biology 2023-03-14 Yu-Jia An , Sheng-Chen Bai , Lin Cheng , Xiao-Guang Li , Cheng-en Wang , Xiao-Dong Han , Gang Su , Shi-Ju Ran , Cong Wang

Infectious diseases spread through human networks. Susceptible-Infected-Removed (SIR) model is one of the epidemic models to describe infection dynamics on a complex network connecting individuals. In the metapopulation SIR model, each node…

Physics and Society · Physics 2015-08-27 Kanako Mizuno , Kazue Kudo

Since infectious pathogens start spreading into a susceptible population, mathematical models can provide policy makers with reliable forecasts and scenario analyses, which can be concretely implemented or solely consulted. In these complex…

Numerical Analysis · Mathematics 2024-04-30 Giovanni Ziarelli , Nicola Parolini , Marco Verani

Agent Based Models (ABMs) have emerged as a powerful tool for investigating complex social interactions, particularly in the context of public health and infectious disease investigation. In an effort to enhance the conventional ABM,…

Multiagent Systems · Computer Science 2024-03-12 Sijin Zhang , Alvaro Orsi , Lei Chen

Early and accurate diagnosis of interstitial lung diseases (ILDs) is crucial for making treatment decisions, but can be challenging even for experienced radiologists. The diagnostic procedure is based on the detection and recognition of the…

Computer Vision and Pattern Recognition · Computer Science 2018-04-02 Marios Anthimopoulos , Stergios Christodoulidis , Lukas Ebner , Thomas Geiser , Andreas Christe , Stavroula Mougiakakou
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