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Infectious diseases pose significant human and economic burdens. Accurately forecasting disease incidence can enable public health agencies to respond effectively to existing or emerging diseases. Despite progress in the field, developing…

Machine Learning · Computer Science 2024-09-04 Michael Morris

In this paper, we present a new approach to time series forecasting. Time series data are prevalent in many scientific and engineering disciplines. Time series forecasting is a crucial task in modeling time series data, and is an important…

Machine Learning · Computer Science 2020-01-24 Neo Wu , Bradley Green , Xue Ben , Shawn O'Banion

Forecasting influenza like illnesses (ILI) has rapidly progressed in recent years from an art to a science with a plethora of data-driven methods. While these methods have achieved qualified success, their applicability is limited due to…

Machine Learning · Computer Science 2021-01-26 Alexander Rodríguez , Bijaya Adhikari , Naren Ramakrishnan , B. Aditya Prakash

We present a machine learning-based methodology capable of providing real-time ("nowcast") and forecast estimates of influenza activity in the US by leveraging data from multiple data sources including: Google searches, Twitter microblogs,…

Applications · Statistics 2016-02-17 Mauricio Santillana , Andre T. Nguyen , Mark Dredze , Michael J. Paul , John S. Brownstein

Seasonal influenza epidemics cause consistent, considerable, widespread loss annually in terms of economic burden, morbidity, and mortality. With access to accurate and reliable forecasts of a current or upcoming influenza epidemic's…

Populations and Evolution · Quantitative Biology 2016-02-17 Logan C. Brooks , David C. Farrow , Sangwon Hyun , Ryan J. Tibshirani , Roni Rosenfeld

Accurately forecasting county level COVID-19 confirmed cases is crucial to optimizing medical resources. Forecasting emerging outbreaks pose a particular challenge because many existing forecasting techniques learn from historical seasons…

The annual influenza outbreak leads to significant public health and economic burdens making it desirable to have prompt and accurate probabilistic forecasts of the disease spread. The United States Centers for Disease Control and…

Applications · Statistics 2025-08-29 Spencer Wadsworth , Jarad Niemi

Accurate epidemic forecasting is critical for informing public health decisions and timely interventions. While Physics-Informed Neural Networks have shown promise in various scientific domains, their potential application to real-time…

Physics and Society · Physics 2026-05-20 Martina Rama , Gabriele Santin , Giulia Cencetti , Michele Tizzoni , Bruno Lepri

Tuberculosis (TB) remains a formidable global health challenge, driven by complex spatiotemporal transmission dynamics and influenced by factors such as population mobility and behavioral changes. We propose an Epidemic-Guided Deep Learning…

Machine Learning · Computer Science 2025-10-29 Madhab Barman , Madhurima Panja , Nachiketa Mishra , Tanujit Chakraborty

Background: Over the past few decades, numerous forecasting methods have been proposed in the field of epidemic forecasting. Such methods can be classified into different categories such as deterministic vs. probabilistic, comparative…

Seasonal influenza forecasting is critical for public health and individual decision making. We investigate whether the inclusion of data about influenza activity in neighboring states can improve point predictions and distribution…

Applications · Statistics 2024-08-26 Gabrielle Thivierge , Aaron Rumack , F. William Townes

Forecasting influenza in a timely manner aids health organizations and policymakers in adequate preparation and decision making. However, effective influenza forecasting still remains a challenge despite increasing research interest. It is…

Influenza remains a significant burden on health systems. Effective responses rely on the timely understanding of the magnitude and the evolution of an outbreak. For monitoring purposes, data on severe cases of influenza in England are…

Accurate and reliable forecasting of epidemic incidences is critical for public health preparedness, yet it remains a challenging task due to complex nonlinear temporal dependencies and heterogeneous spatial interactions. Often, point…

Machine Learning · Statistics 2026-03-10 Rajdeep Pathak , Tanujit Chakraborty

Advancing epidemic dynamics forecasting is vital for targeted interventions and safeguarding public health. Current approaches mainly fall into two categories: mechanism-based and data-driven models. Mechanism-based models are constrained…

Machine Learning · Computer Science 2025-08-05 Rui Sun , Chenghua Gong , Tianjun Gu , Yuhao Zheng , Jie Ding , Juyuan Zhang , Liming Pan , Linyuan Lü

Seasonal influenza infects between 10 and 50 million people in the United States every year, overburdening hospitals during weeks of peak incidence. Named by the CDC as an important tool to fight the damaging effects of these epidemics,…

Applications · Statistics 2020-05-19 Thomas McAndrew , Nicholas G. Reich

Public health surveillance systems often fail to detect emerging infectious diseases, particularly in resource limited settings. By integrating relevant clinical and internet-source data, we can close critical gaps in coverage and…

Applications · Statistics 2019-03-05 Kai Liu , Ravi Srinivasan , Lauren Ancel Meyers

The accurate forecasting of infectious epidemic diseases is the key to effective control of the epidemic situation in a region. Most existing methods ignore potential dynamic dependencies between regions or the importance of temporal…

Machine Learning · Computer Science 2022-08-25 Feng Xie , Zhong Zhang , Xuechen Zhao , Bin Zhou , Yusong Tan

Influenza is an infectious disease with the potential to become a pandemic, and hence, forecasting its prevalence is an important undertaking for planning an effective response. Research has found that web search activity can be used to…

Machine Learning · Computer Science 2021-05-27 Michael Morris , Peter Hayes , Ingemar J. Cox , Vasileios Lampos

We introduce EINNs, a framework crafted for epidemic forecasting that builds upon the theoretical grounds provided by mechanistic models as well as the data-driven expressibility afforded by AI models, and their capabilities to ingest…

Machine Learning · Computer Science 2023-01-12 Alexander Rodríguez , Jiaming Cui , Naren Ramakrishnan , Bijaya Adhikari , B. Aditya Prakash
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