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This paper presents a new method for medical diagnosis of neurodegenerative diseases, such as Parkinson's, by extracting and using latent information from trained Deep convolutional, or convolutional-recurrent Neural Networks (DNNs). In…

Machine Learning · Computer Science 2019-01-24 Ilianna Kollia , Andreas-Georgios Stafylopatis , Stefanos Kollias

While convolutional neural networks (CNNs) have been successfully applied to many challenging classification applications, they typically require large datasets for training. When the availability of labeled data is limited, data…

Computer Vision and Pattern Recognition · Computer Science 2017-11-10 Terry Taewoong Um , Franz Michael Josef Pfister , Daniel Pichler , Satoshi Endo , Muriel Lang , Sandra Hirche , Urban Fietzek , Dana Kulić

Speech holds promise as a cost-effective and non-invasive biomarker for neurological conditions such as Parkinson's disease (PD). While deep learning systems trained on raw audio can find subtle signals not available from hand-crafted…

Audio and Speech Processing · Electrical Eng. & Systems 2025-07-24 Peter Plantinga , Jen-Kai Chen , Roozbeh Sattari , Mirco Ravanelli , Denise Klein

Dysphonia is one of the early symptoms of Parkinson's disease (PD). Most existing methods use feature selection methods to find the optimal subset of voice features for all PD patients. Few have considered the heterogeneity between…

Machine Learning · Computer Science 2022-08-15 Zaifa Xue , Huibin Lu , Tao Zhang , Max A. Little

In this paper, we envision a web-based framework that can help anyone, anywhere around the world record a short speech task, and analyze the recorded data to screen for Parkinson's disease (PD). We collected data from 726 unique…

People with Parkinson's disease must be regularly monitored by their physician to observe how the disease is progressing and potentially adjust treatment plans to mitigate the symptoms. Monitoring the progression of the disease through a…

Audio and Speech Processing · Electrical Eng. & Systems 2022-05-25 Mohammadreza Iman , Amy Giuntini , Hamid Reza Arabnia , Khaled Rasheed

Local polynomial regression struggles with several challenges when dealing with sparse data. The difficulty in capturing local features of the underlying function can lead to a potential misrepresentation of the true relationship.…

Methodology · Statistics 2025-05-02 Chunlei Ge , W. John Braun

Parkinson's disease (PD) is a debilitating neurological disorder that necessitates precise and early diagnosis for effective patient care. This study aims to develop a diagnostic model capable of achieving both high accuracy and minimizing…

Machine Learning · Computer Science 2024-01-30 Seyedeh Zahra Seyedi Hosseininian , Ahmadreza Tajari , Mohsen Ghalehnoie , Alireza Alfi

This work aims to tackle the Parkinson's disease (PD) detection problem from the speech signal in a bilingual setting by proposing an ad-hoc dual-head deep neural architecture for type-based binary classification. One head is specialized…

Audio and Speech Processing · Electrical Eng. & Systems 2025-11-13 Moreno La Quatra , Juan Rafael Orozco-Arroyave , Marco Sabato Siniscalchi

A popular approach within the signal processing and machine learning communities consists in modelling signals as sparse linear combinations of atoms selected from a learned dictionary. While this paradigm has led to numerous empirical…

Machine Learning · Computer Science 2015-08-25 Rémi Gribonval , Rodolphe Jenatton , Francis Bach

This paper enhances dysarthric and dysphonic speech recognition by fine-tuning pretrained automatic speech recognition (ASR) models on the 2023-10-05 data package of the Speech Accessibility Project (SAP), which contains the speech of 253…

Audio and Speech Processing · Electrical Eng. & Systems 2024-10-01 Xiuwen Zheng , Bornali Phukon , Mark Hasegawa-Johnson

Parkinson's disease is a neurodegenerative disorder that can be very tricky to diagnose and treat. Such early symptoms can include tremors, wheezy breathing, and changes in voice quality as critical indicators of neural damage. Notably,…

Sound · Computer Science 2025-11-20 Abishek Karthik , Pandiyaraju V , Dominic Savio M , Rohit Swaminathan S

Parkinson's disease (PD) is a progressive neurodegenerative disorder that, in addition to directly impairing functional mobility, is frequently associated with vocal impairments such as hypophonia and dysarthria, which typically manifest in…

Parkinson's disease (PD), the second most common neurodegenerative disorder, is characterized by dopaminergic neuron loss and the accumulation of abnormal synuclein. PD presents both motor and non-motor symptoms that progressively impair…

Machine Learning · Computer Science 2025-04-07 Masahiro Matsumoto , Abu Saleh Musa Miah , Nobuyoshi Asai , Jungpil Shin

Sparse Representation (SR) of signals or data has a well founded theory with rigorous mathematical error bounds and proofs. SR of a signal is given by superposition of very few columns of a matrix called Dictionary, implicitly reducing…

Computer Vision and Pattern Recognition · Computer Science 2026-04-01 G. Madhuri , Atul Negi

Parkinsons disease (PD) is a debilitating motor system disorder characterized by progressive loss of movement, tremors, and speech slurring. PD is due to the loss of dopamine-producing brain cells, and symptoms only worsen over time, making…

Neurons and Cognition · Quantitative Biology 2014-05-07 Pooja Chandrashekar

In recent years, there are many research cases for the diagnosis of Parkinson's disease (PD) with the brain magnetic resonance imaging (MRI) by utilizing the traditional unsupervised machine learning methods and the supervised deep learning…

Image and Video Processing · Electrical Eng. & Systems 2020-03-11 Xiaobo Zhang , Donghai Zhai , Yan Yang , Yiling Zhang , Chunlin Wang

Patient similarity assessment (PSA) is pivotal to evidence-based and personalized medicine, enabled by analyzing the increasingly available electronic health records (EHRs). However, machine learning approaches for PSA has to deal with…

Machine Learning · Computer Science 2022-02-04 Xian Wei , See Kiong Ng , Tongtong Zhang , Yingjie Liu

Background and Objective: Parkinson's disease (PD) is the second most common progressive neurological condition after Alzheimer's, characterized by motor and non-motor symptoms. Developing a method to diagnose the condition in its beginning…

Machine Learning · Computer Science 2022-10-05 Paria Ghaheri , Hamid Nasiri , Ahmadreza Shateri , Arman Homafar

Speech production is a complex phenomenon, wherein the brain orchestrates a sequence of processes involving thought processing, motor planning, and the execution of articulatory movements. However, this intricate execution of various…

Audio and Speech Processing · Electrical Eng. & Systems 2024-06-06 Shakeel Ahmad Sheikh