Related papers: Generating Digital Twins with Multiple Sclerosis U…
The aim of the systematic review was to assess recently published studies on diagnostic test accuracy of glioblastoma treatment response monitoring biomarkers in adults, developed through machine learning (ML). Articles were searched for…
Multiple Sclerosis (MS) is a severe neurological disease characterized by inflammatory lesions in the central nervous system. Hence, predicting inflammatory disease activity is crucial for disease assessment and treatment. However, MS…
Over the last couple of years, machine learning parameterizations have emerged as a potential way to improve the representation of sub-grid processes in Earth System Models (ESMs). So far, all studies were based on the same three-step…
Aleatoric uncertainties - irremovable variability in microstructure morphology, constituent behavior, and processing conditions - pose a major challenge to developing uncertainty-robust digital twins. We introduce the Variational Deep…
Digital Twins (DTs) are computational models that simulate the states and temporal dynamics of real-world systems, playing a crucial role in prediction, understanding, and decision-making across diverse domains. However, existing approaches…
Serious games have proven to be effective tools for screening cognitive impairments and supporting diagnosis in patients with neurodegenerative diseases like Alzheimer's and Parkinson's. They also offer cognitive training benefits.…
We propose a novel online learning algorithm for Restricted Boltzmann Machines (RBM), namely, the Online Generative Discriminative Restricted Boltzmann Machine (OGD-RBM), that provides the ability to build and adapt the network architecture…
Estimating the log-likelihood gradient with respect to the parameters of a Restricted Boltzmann Machine (RBM) typically requires sampling using Markov Chain Monte Carlo (MCMC) techniques. To save computation time, the Markov chains are only…
Restricted Boltzmann Machine (RBM) is an importan- t generative model modeling vectorial data. While applying an RBM in practice to images, the data have to be vec- torized. This results in high-dimensional data and valu- able spatial…
Modern datasets are becoming heterogeneous. To this end, we present in this paper Mixed-Variate Restricted Boltzmann Machines for simultaneously modelling variables of multiple types and modalities, including binary and continuous…
This work analyzes centered binary Restricted Boltzmann Machines (RBMs) and binary Deep Boltzmann Machines (DBMs), where centering is done by subtracting offset values from visible and hidden variables. We show analytically that (i)…
Clinical trials are critical in advancing medical treatments but often suffer from immense time and financial burden. Advances in statistical methodologies and artificial intelligence (AI) present opportunities to address these…
Restricted Boltzmann Machines (RBMs) are generative models designed to learn from data with a rich underlying structure. In this work, we explore a teacher-student setting where a student RBM learns from examples generated by a teacher RBM,…
Machine Learning (ML) has garnered considerable attention from researchers and practitioners as a new and adaptable tool for disease diagnosis. With the advancement of ML and the proliferation of papers and research in this field, a…
Restricted Boltzmann Machines (RBMs) are widely used probabilistic undirected graphical models with visible and latent nodes, playing an important role in statistics and machine learning. The task of structure learning for RBMs involves…
We extend the framework of Boltzmann machines to a network of complex-valued neurons with variable amplitudes, referred to as Complex Amplitude-Phase Boltzmann machine (CAP-BM). The model is capable of performing unsupervised learning on…
Background and purpose: The unanticipated detection by magnetic resonance imaging (MRI) in the brain of asymptomatic subjects of white matter lesions suggestive of multiple sclerosis (MS) has been named radiologically isolated syndrome…
Liver cirrhosis is a major global health problem causing millions of deaths annually, and timely detection with aggressive treatment can significantly improve patients' quality of life. Modelling complex diseases from biomedical data is…
Understanding the intensity characteristics of brain lesions is key for defining image-based biomarkers in neurological studies and for predicting disease burden and outcome. In this work, we present a novel foreground-based generative…
Digital twins (DTs), serving as the core enablers for real-time monitoring and predictive maintenance of complex cyber-physical systems, impose critical requirements on their virtual models: high predictive accuracy, strong…