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Background: An early diagnosis together with an accurate disease progression monitoring of multiple sclerosis is an important component of successful disease management. Prior studies have established that multiple sclerosis is correlated…

Audio and Speech Processing · Electrical Eng. & Systems 2021-09-28 Emil Svoboda , Tomáš Bořil , Jan Rusz , Tereza Tykalová , Dana Horáková , Charles R. G. Guttman , Krastan B. Blagoev , Hiroto Hatabu , Vlad I. Valtchinov

Clinical trials are indispensable for medical research and the development of new treatments. However, clinical trials often involve thousands of participants and can span several years to complete, with a high probability of failure during…

Machine Learning · Computer Science 2024-07-02 Yue Wang , Tianfan Fu , Yinlong Xu , Zihan Ma , Hongxia Xu , Yingzhou Lu , Bang Du , Honghao Gao , Jian Wu

Multi-modal magnetic resonance imaging (MRI) provides rich, complementary information for analyzing diseases. However, the practical challenges of acquiring multiple MRI modalities, such as cost, scan time, and safety considerations, often…

Image and Video Processing · Electrical Eng. & Systems 2024-09-16 Zhaohu Xing , Sicheng Yang , Sixiang Chen , Tian Ye , Yijun Yang , Jing Qin , Lei Zhu

Restricted Boltzmann Machines (RBMs) and Deep Belief Networks have been demonstrated to perform efficiently in a variety of applications, such as dimensionality reduction, feature learning, and classification. Their implementation on…

Neural and Evolutionary Computing · Computer Science 2015-11-17 Emre Neftci , Srinjoy Das , Bruno Pedroni , Kenneth Kreutz-Delgado , Gert Cauwenberghs

Here, we propose a novel method for representation of general spin systems using Restricted Boltzmann Machine with Softmax Regression (SRBM) that follows the probability distribution of the training data. SRBM training is performed using…

Disordered Systems and Neural Networks · Physics 2023-04-25 Abhiroop Lahiri , Shazia Janwari , Swapan K Pati

A framework for creating and updating digital twins for dynamical systems from a library of physics-based functions is proposed. The sparse Bayesian machine learning is used to update and derive an interpretable expression for the digital…

Machine Learning · Statistics 2022-12-20 Tapas Tripura , Aarya Sheetal Desai , Sondipon Adhikari , Souvik Chakraborty

Many disciplines need quantitative models that synthesize experimental data across multiple instances of the same general system. For example, neuroscientists must combine data from the brains of many individual animals to understand the…

Machine Learning · Computer Science 2026-03-17 William E. Bishop , Luuk W. Hesselink , Bernhard Englitz , Misha B. Ahrens , James E. Fitzgerald

Diabetic Retinopathy (DR) is a non-negligible eye disease among patients with Diabetes Mellitus, and automatic retinal image analysis algorithm for the DR screening is in high demand. Considering the resolution of retinal image is very…

Computer Vision and Pattern Recognition · Computer Science 2019-11-14 Kang Zhou , Zaiwang Gu , Wen Liu , Weixin Luo , Jun Cheng , Shenghua Gao , Jiang Liu

Restricted Boltzmann Machines (RBMs) and models derived from them have been successfully used as basic building blocks in deep artificial neural networks for automatic features extraction, unsupervised weights initialization, but also as…

Neural and Evolutionary Computing · Computer Science 2016-07-20 Decebal Constantin Mocanu , Elena Mocanu , Phuong H. Nguyen , Madeleine Gibescu , Antonio Liotta

Lesion segmentation is a core task for quantitative analysis of MRI scans of Multiple Sclerosis patients. The recent success of deep learning techniques in a variety of medical image analysis applications has renewed community interest in…

Image and Video Processing · Electrical Eng. & Systems 2020-12-29 Huahong Zhang , Ipek Oguz

Boltzmann Machines (BMs) are graphical models with interconnected binary units, employed for the unsupervised modeling of data distributions. When trained on real data, BMs show the tendency to behave like critical systems, displaying a…

Disordered Systems and Neural Networks · Physics 2024-06-28 Enrico Ventura , Simona Cocco , Rémi Monasson , Francesco Zamponi

To date, several automated strategies for identification/segmentation of Multiple Sclerosis (MS) lesions with the use of Magnetic Resonance Imaging (MRI) have been presented, but they are outperformed by human experts, from whom they act…

Image and Video Processing · Electrical Eng. & Systems 2022-06-22 Giuseppe Placidi , Luigi Cinque , Daniela Iacoviello , Filippo Mignosi , Matteo Polsinelli

Restricted Boltzmann Machines (RBM) have attracted a lot of attention of late, as one the principle building blocks of deep networks. Training RBMs remains problematic however, because of the intractibility of their partition function. The…

Machine Learning · Statistics 2010-12-17 Guillaume Desjardins , Aaron Courville , Yoshua Bengio

Current large scale implementations of deep learning and data mining require thousands of processors, massive amounts of off-chip memory, and consume gigajoules of energy. Emerging memory technologies such as nanoscale two-terminal…

Neural and Evolutionary Computing · Computer Science 2016-11-15 S. Burc Eryilmaz , Emre Neftci , Siddharth Joshi , SangBum Kim , Matthew BrightSky , Hsiang-Lan Lung , Chung Lam , Gert Cauwenberghs , H. -S. Philip Wong

Accurate detection and segmentation of brain tumors is critical for medical diagnosis. However, current supervised learning methods require extensively annotated images and the state-of-the-art generative models used in unsupervised methods…

Image and Video Processing · Electrical Eng. & Systems 2023-11-07 Wenxin Wang , Zhuo-Xu Cui , Guanxun Cheng , Chentao Cao , Xi Xu , Ziwei Liu , Haifeng Wang , Yulong Qi , Dong Liang , Yanjie Zhu

Many computer vision applications involve modeling complex spatio-temporal patterns in high-dimensional motion data. Recently, restricted Boltzmann machines (RBMs) have been widely used to capture and represent spatial patterns in a single…

Computer Vision and Pattern Recognition · Computer Science 2017-10-24 Siqi Nie , Ziheng Wang , Qiang Ji

Restricted Boltzmann Machines (RBMs) are generative models which can learn useful representations from samples of a dataset in an unsupervised fashion. They have been widely employed as an unsupervised pre-training method in machine…

Machine Learning · Statistics 2013-09-13 Chris Häusler , Alex Susemihl , Martin P Nawrot , Manfred Opper

Importance: The prevalence of severe mental illnesses (SMIs) in the United States is approximately 3% of the whole population. The ability to conduct risk screening of SMIs at large scale could inform early prevention and treatment.…

Artificial Intelligence · Computer Science 2023-01-13 Dianbo Liu , Karmel W. Choi , Paulo Lizano , William Yuan , Kun-Hsing Yu , Jordan W. Smoller , Isaac Kohane

Geometric frustration gives rise to emergent quantum phenomena and exotic phases of matter. While Monte Carlo methods are traditionally used to simulate such systems, their sampling efficiency is limited by the complexity of interactions…

Statistical Mechanics · Physics 2025-11-27 Pratik Brahma , Junghoon Han , Tamzid Razzaque , Saavan Patel , Sayeef Salahuddin

Personalized head and neck cancer therapeutics have greatly improved survival rates for patients, but are often leading to understudied long-lasting symptoms which affect quality of life. Sequential rule mining (SRM) is a promising…

Human-Computer Interaction · Computer Science 2023-09-28 Carla Floricel , Andrew Wentzel , Abdallah Mohamed , C. David Fuller , Guadalupe Canahuate , G. Elisabeta Marai