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Surface plasmon resonance (SPR) is generally observed by excitation of surface plasmon polaritons on the metal (Au/Ag) surface. In order to utilize the SPR phenomenon for sensing application, the metal surface is functionalized with…

Optics · Physics 2022-12-20 Amrit Kumar , Manjuladevi V , R. K. Gupta

Surface Plasmon Resonance (SPR) is an important bio-sensing technique for real-time label-free detection. However, it is pivotal to optimize various parameters of the sensor configuration for efficient and highly sensitive sensing. To that…

Biological Physics · Physics 2020-07-20 Ehsan Kabir , Syed Mohammad Ashab Uddin , Sayeed Shafayet Chowdhury

Surface Plasmon Resonance (SPR) offers a powerful tool for label-free and non-invasive characterization of biomolecular interactions. To date, several experimental configurations, based on two fundamental physical phenomena, e.g.,…

Optics · Physics 2022-11-15 Nishant Shukla , Pawan Chetri , Ratan Boruah , Ankur Gogoi , Gazi A Ahmed

Sensors based on the phenomenon of surface plasmon resonance have limited sensitivity, up to 123 degree/Refractive Index Unit, which restricts their applicability in detecting subtle changes gin biological media (around 10-5 RIU). To…

Optics · Physics 2026-01-12 Rostyslav Terekhov , Zoya Eremenko , Sergii Kulish

This paper presents a comprehensive study on a novel multilayer surface plasmon resonance (SPR) biosensor designed for detecting trace-level toxins in liquid samples with exceptional precision and efficiency. Leveraging the Kretschmann…

Systems and Control · Electrical Eng. & Systems 2025-01-31 Suripto Bhuiyan , Michael Geller

A broadband detection method with coherent laser pulses exciting surface plasmons is investigated. The intensity and phase characteristics of the reflected light in Kretschmann configuration are calculated. It is shown that by mixing…

Instrumentation and Detectors · Physics 2018-11-14 Alexandre Kolomenskii , Elizabeth Surovic , Hans Schuessler

A surface plasmon resonance imaging biosensor based on $\text{MoS}_2$ deposited on Aluminium substrate is designed for high imaging sensitivity and detection accuracy. The proposed biosensor exhibits better performance than graphene-based…

Mesoscale and Nanoscale Physics · Physics 2018-12-19 Yi Xu , Lin Wu , Lay Kee Ang

We report on a Surface-Plasmon-Resonance (SPR) technique based on Fourier -Transform - Infra - Red (FTIR) spectrometer. In contrast to the conventional surface plasmon technique, operating at a fixed wavelength and a variable angle of…

Soft Condensed Matter · Physics 2013-03-19 V. Lirtsman , M. Golosovsky , D. Davidov

This work presents a high-performance, multilayered surface plasmon resonance (SPR)-based sensor designed to enhance performance parameters in the near-infrared (NIR) region through angular interrogation. The multi-layered sensor consists…

Optics · Physics 2025-11-11 R. Runthala , N. Grover , P. Arora

This report investigates design enhancements of Fiber Optic Surface Plasmon Resonance (FO-SPR) biosensors with Gold and Silver metallic films. The effect of adding a Graphene coating on the sensitivity and detection accuracy of FO-SPR…

Applied Physics · Physics 2019-07-17 Mariam M. Moussilli , Abdul Rahman El Falou , Raed M. Shubair

Inspired by the classic theory, we suggest that the performance of a D-shaped fiber optical surface plasmon resonance (SPR) sensor can be improved by manipulating the fiber core mode. To demonstrate this, we propose a novel fiber SPR sensor…

Applied Physics · Physics 2018-05-16 Zhixin Tan , Xuejin Li , Yuzhi Chen , Ping Fan

Surface plasmon resonance (SPR) has been widely utilized to improve the absorption performance in the photosensors. Graphene has emerged as a promising plasmonic material, which supports tunable SPR and shows significant flexibility over…

Optics · Physics 2018-09-11 Shuyuan Xiao , Tao Wang , Xiaoyun Jiang , Boyun Wang , Chen Xu

Spectroscopic analysis of large biomolecules is critical in a number of applications, including medical diagnostics and label-free biosensing. Recently, it has been shown that Raman spectroscopy of proteins can be used to diagnose some…

In this paper we report a fiber optical sensor system based on surface plasmon resonance (SPR) with real-time response for biochemical interaction analysis. The fiber sensor is constructed from a multi-mode fiber with plastic cladding. To…

Applied Physics · Physics 2019-05-10 Zhixin Tan , Xuejin Li , Yuzhi Chen , Ping Fan

We discuss the Surface-Plasmon-Resonance (SPR) technique based on Fourier -Transform - InfraRed (FTIR) spectrometry. We explore the potential of the infrared surface plasmon resonance technique for biological studies in aqueous solutions…

Biological Physics · Physics 2010-02-03 M. Golosovsky , V. Lirtsman , V. Yashunsky , D. Davidov , B. Aroeti

We show that for the optimized angle of incidence, the SPR based optical sensors exhibit dual resonance in the near-infrared region around which the sensor becomes exceptionally high sensitive. Both the resonances show opposite spectral…

Optics · Physics 2020-07-07 Indrajeet Kumar , Ranjeet Dwivedi , Saurabh Mani Tripathi

We present a numerical study of a divergent-beam Kretschmann surface plasmon resonance (SPR) platform for multiplexed malaria biosensing. A Powell-lens-generated angular fan enables camera-based angular interrogation of spatially separated…

Optics · Physics 2026-04-22 Amos. S. Kiyumbi , Jordan. H. Hossea

We present a simulation guided design for a multilayer surface plasmon resonance (SPR) based biosensor capable of detecting refractive index changes in a target induced by analytes. Surface plasmons are excited using a hybrid Kretschmann…

Optics · Physics 2025-12-23 R. Runthala , V. K. Venkatesh , D. Gupta , P. Arora

The use of graphene in surface plasmon resonance sensors, covering a metallic (plasmonic) film, has a number of demonstrated advantages, such protecting the film against corrosion/oxidation and facilitating the introduction of functional…

Mesoscale and Nanoscale Physics · Physics 2022-10-26 Aline dos S. Almeida , D. A. Bahamon , Nuno M. R. Peres , Christiano J. S. de Matos

Spectroscopic ellipsometry is a sensitive and optical model-supported quantitative tool to monitor interfaces. In this work, solid-liquid interfaces are studied using the Kretschmann-Raether configuration for biosensing applications. The…

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