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Histogram-based empirical Bayes methods developed for analyzing data for large numbers of genes, SNPs, or other biological features tend to have large biases when applied to data with a smaller number of features such as genes with…

Methodology · Statistics 2013-10-10 Marta Padilla , David R. Bickel

Cluster randomized trials (CRTs) frequently recruit a small number of clusters, therefore necessitating the application of small-sample corrections for valid inference. A recent systematic review indicated that CRTs reporting…

Methodology · Statistics 2022-09-07 Xueqi Wang , Elizabeth L. Turner , Fan Li

The quantization of large language models (LLMs) has been a prominent research area aimed at enabling their lightweight deployment in practice. Existing research about LLM's quantization has mainly explored the interplay between weights and…

Computation and Language · Computer Science 2025-05-16 Yifei Gao , Jie Ou , Lei Wang , Jun Cheng , Mengchu Zhou

We study optimal variance reduction solutions for count and ratio metrics in online controlled experiments. Our methods leverage flexible machine learning tools to incorporate covariates that are independent from the treatment but have…

Methodology · Statistics 2022-09-05 Ying Jin , Shan Ba

Latent variable models have been widely applied in different fields of research in which the constructs of interest are not directly observable, so that one or more latent variables are required to reduce the complexity of the data. In…

Statistics Theory · Mathematics 2014-07-07 Silvia Bianconcini

Variational inference has become one of the most widely used methods in latent variable modeling. In its basic form, variational inference employs a fully factorized variational distribution and minimizes its KL divergence to the posterior.…

Machine Learning · Statistics 2020-01-29 Robert Bamler , Cheng Zhang , Manfred Opper , Stephan Mandt

Linear Vector AutoRegressive (VAR) models where the innovations could be unconditionally heteroscedastic and serially dependent are considered. The volatility structure is deterministic and quite general, including breaks or trending…

Methodology · Statistics 2010-07-09 Valentin Patilea , Hamdi Raïssi

Attenuation bias -- the systematic underestimation of regression coefficients due to measurement errors in input variables -- affects astronomical data-driven models. For linear regression, this problem was solved by treating the true input…

Instrumentation and Methods for Astrophysics · Physics 2026-03-30 Yuan-Sen Ting

In high-stakes domains, small task-specific vision models are crucial due to their low computational requirements and the availability of numerous methods to explain their results. However, these explanations often reveal that the models do…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Alexander Koebler , Lukas Kuhn , Ingo Thon , Florian Buettner

Random-effects models are frequently used to synthesise information from different studies in meta-analysis. While likelihood-based inference is attractive both in terms of limiting properties and of implementation, its application in…

Methodology · Statistics 2018-02-16 Ioannis Kosmidis , Annamaria Guolo , Cristiano Varin

Inference about a scalar parameter of interest is a core statistical task that has attracted immense research in statistics. The Wald statistic is a prime candidate for the task, on the grounds of the asymptotic validity of the standard…

Methodology · Statistics 2019-03-12 C. Di Caterina , I. Kosmidis

Randomized experiments or randomized controlled trials (RCTs) are gold standards for causal inference, yet cost and sample-size constraints limit power. We introduce CALM (Causal Analysis leveraging Language Models), a statistical framework…

Methodology · Statistics 2025-12-09 Xinrui Ruan , Xinwei Ma , Yingfei Wang , Waverly Wei , Jingshen Wang

In testing of hypothesis the robustness of the tests is an important concern. Generally, the maximum likelihood based tests are most efficient under standard regularity conditions, but they are highly non-robust even under small deviations…

Methodology · Statistics 2018-05-01 Ayanendranath Basu , Abhijit Mandal , Nirian Martin , Leandro Pardo

Unsupervised estimation of latent variable models is a fundamental problem central to numerous applications of machine learning and statistics. This work presents a principled approach for estimating broad classes of such models, including…

Machine Learning · Statistics 2013-05-27 Animashree Anandkumar , Daniel Hsu , Adel Javanmard , Sham M. Kakade

Vision-language models (VLMs) frequently generate hallucinated content plausible but incorrect claims about image content. We propose a training-free self-correction framework enabling VLMs to iteratively refine responses through…

Computer Vision and Pattern Recognition · Computer Science 2025-12-11 Kassoum Sanogo , Renzo Ardiccioni

Latent variable models are popularly used to measure latent factors (e.g., abilities and personalities) from large-scale assessment data. Beyond understanding these latent factors, the covariate effect on responses controlling for latent…

Methodology · Statistics 2026-01-12 Jing Ouyang , Chengyu Cui , Kean Ming Tan , Gongjun Xu

A common task in high-throughput biology is to test for differences in means between two samples across thousands of features (e.g., genes or proteins), often with only a handful of replicates per sample. Moderated t-tests handle this…

Methodology · Statistics 2025-10-02 Wanyi Ling , Wufang Hong , Nikolaos Ignatiadis

Researchers now routinely use AI or other machine learning methods to estimate latent variables of economic interest, then plug-in the estimates as covariates in a regression. We show both theoretically and empirically that naively treating…

Econometrics · Economics 2025-05-01 Laura Battaglia , Timothy Christensen , Stephen Hansen , Szymon Sacher

We consider the problem of automatic variable selection in a linear model with asymmetric or heavy-tailed errors when the number of explanatory variables diverges with the sample size. For this high-dimensional model, the penalized least…

Statistics Theory · Mathematics 2018-12-10 Gabriela Ciuperca

Estimating covariances between financial assets plays an important role in risk management. In practice, when the sample size is small compared to the number of variables, the empirical estimate is known to be very unstable. Here, we…

Computational Engineering, Finance, and Science · Computer Science 2019-04-19 Rajbir-Singh Nirwan , Nils Bertschinger
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