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Abstraction is a desirable capability for deep learning models, which means to induce abstract concepts from concrete instances and flexibly apply them beyond the learning context. At the same time, there is a lack of clear understanding…

Machine Learning · Computer Science 2023-02-24 Shengnan An , Zeqi Lin , Bei Chen , Qiang Fu , Nanning Zheng , Jian-Guang Lou

We present a differentiable formulation of abstract chemical reaction networks (CRNs) that can be trained to solve a variety of computational tasks. Chemical reaction networks are one of the most fundamental computational substrates used by…

Molecular Networks · Quantitative Biology 2023-02-07 Alexander Mordvintsev , Ettore Randazzo , Eyvind Niklasson

Deep Kernel Learning (DKL) combines the representational power of neural networks with the uncertainty quantification of Gaussian Processes. Hence, it is potentially a promising tool to learn and control complex dynamical systems. In this…

Systems and Control · Electrical Eng. & Systems 2024-03-14 Robert Reed , Luca Laurenti , Morteza Lahijanian

Deep neural networks are powerful learning models that achieve state-of-the-art performance on many computer vision, speech, and language processing tasks. In this paper, we study a fundamental question that arises when designing deep…

Machine Learning · Statistics 2017-10-24 Shiva Prasad Kasiviswanathan , Nina Narodytska , Hongxia Jin

Background: Automatic extraction of chemical-disease relations (CDR) from unstructured text is of essential importance for disease treatment and drug development. Meanwhile, biomedical experts have built many highly-structured knowledge…

Computation and Language · Computer Science 2019-12-24 Huiwei Zhou , Chengkun Lang , Zhuang Liu , Shixian Ning , Yingyu Lin , Lei Du

In this paper, it is presented a methodology for implementing arbitrarily constructed time-homogenous Markov chains with biochemical systems. Not only discrete but also continuous-time Markov chains are allowed to be computed. By employing…

Molecular Networks · Quantitative Biology 2018-02-16 Chuan Zhang , Ziyuan Shen , Wei Wei , Jing Zhao , Zaichen Zhang , Xiaohu You

Chemical reaction networks (CRNs) are fundamental computational models used to study the behavior of chemical reactions in well-mixed solutions. They have been used extensively to model a broad range of biological systems, and are primarily…

Molecular Networks · Quantitative Biology 2021-05-13 J. N. Mueller , J. N. Corcoran

This paper studies the (discrete) \emph{chemical reaction network (CRN)} computational model that emerged in the last two decades as an abstraction for molecular programming. The correctness of CRN protocols is typically established under…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-07-04 Anne Condon , Yuval Emek , Noga Harlev

Abstraction is a key verification technique to improve scalability. However, its use for neural networks is so far extremely limited. Previous approaches for abstracting classification networks replace several neurons with one of them that…

Logic in Computer Science · Computer Science 2023-07-21 Calvin Chau , Jan Křetínský , Stefanie Mohr

The intrinsic complexity of deep neural networks (DNNs) makes it challenging to verify not only the networks themselves but also the hosting DNN-controlled systems. Reachability analysis of these systems faces the same challenge. Existing…

Machine Learning · Computer Science 2023-11-01 Jiaxu Tian , Dapeng Zhi , Si Liu , Peixin Wang , Guy Katz , Min Zhang

Efficient processing of large-scale time series data is an intricate problem in machine learning. Conventional sensor signal processing pipelines with hand engineered feature extraction often involve huge computational cost with high…

In many practical applications, deep neural networks have been typically deployed to operate as a black box predictor. Despite the high amount of work on interpretability and high demand on the reliability of these systems, they typically…

Artificial Intelligence · Computer Science 2020-12-07 Martin Stano , Wanda Benesova , Lukas Samuel Martak

Ground robots which are able to navigate a variety of terrains are needed in many domains. One of the key aspects is the capability to adapt to the ground structure, which can be realized through movable body parts coming along with…

Robotics · Computer Science 2019-03-07 Tobias Klamt , Sven Behnke

We consider how to generate chemical reaction networks (CRNs) from functional specifications. We propose a two-stage approach that combines synthesis by satisfiability modulo theories and Markov chain Monte Carlo based optimisation. First,…

Emerging Technologies · Computer Science 2015-08-19 Neil Dalchau , Niall Murphy , Rasmus Petersen , Boyan Yordanov

This paper is concerned with a compositional approach for constructing infinite abstractions of interconnected discrete-time stochastic control systems. The proposed approach uses the interconnection matrix and joint dissipativity-type…

Systems and Control · Computer Science 2019-05-14 Abolfazl Lavaei , Sadegh Soudjani , Majid Zamani

Stochastic Reaction Networks (SRNs) are a fundamental modeling framework for systems ranging from chemical kinetics and epidemiology to ecological and synthetic biological processes. A central computational challenge is the estimation of…

Molecular Networks · Quantitative Biology 2025-12-09 Quentin Badolle , Arthur Theuer , Zhou Fang , Ankit Gupta , Mustafa Khammash

With the increasing ubiquity of safety-critical autonomous systems operating in uncertain environments, there is a need for mathematical methods for formal verification of stochastic models. Towards formally verifying properties of…

Systems and Control · Electrical Eng. & Systems 2026-02-18 Adrien Banse , Giannis Delimpaltadakis , Luca Laurenti , Manuel Mazo , Raphaël M. Jungers

An abstraction can be used to relate two structural causal models representing the same system at different levels of resolution. Learning abstractions which guarantee consistency with respect to interventional distributions would allow one…

Artificial Intelligence · Computer Science 2023-05-09 Fabio Massimo Zennaro , Máté Drávucz , Geanina Apachitei , W. Dhammika Widanage , Theodoros Damoulas

Whereas distributed computing research has been very successful in exploring the solvability/impossibility border of distributed computing problems like consensus in representative classes of computing models with respect to model…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-05-27 Hugo Rincon Galeana , Ulrich Schmid

Chemical reaction networks (CRN) comprise an important class of models to understand biological functions such as cellular information processing, the robustness and control of metabolic pathways, circadian rhythms, and many more. However,…

Molecular Networks · Quantitative Biology 2025-03-25 Dimitri Loutchko , Yuki Sughiyama , Tetsuya J. Kobayashi