Related papers: Inverse Problems of Single Molecule Localization M…
Super-resolution tasks oriented to images captured in ultra-dark environments is a practical yet challenging problem that has received little attention. Due to uneven illumination and low signal-to-noise ratio in dark environments, a…
Photonic molecules can mimic interactions of atomic energy levels, offering new ways to manipulate cavity eigenstates. Current methods using evanescent coupling of multiple cavities face challenges in scalability, flexibility, and coupling…
We use molecules to couple light into and out of microscale plasmonic waveguides. Energy transfer, mediated by surface plasmons, from donor molecules to acceptor molecules over ten micrometer distances is demonstrated. Also surface plasmon…
We report, for the first time, a multi-confocal Fluorescence Correlation Spectroscopy (mFCS) technique which allows parallel measurements at different locations, by combining a Spatial Light Modulator (SLM), with an Electron Multiplying-CCD…
Photothermal spectroscopy and microscopy provides a route to measure the spectral and spatial properties of individual nanoscopic absorbers, independent from scattering, extinction, and emission. The approach relies upon use of two light…
Multiview super-resolution image reconstruction (SRIR) is often cast as a resampling problem by merging non-redundant data from multiple low-resolution (LR) images on a finer high-resolution (HR) grid, while inverting the effect of the…
Single-pixel imaging can collect images at the wavelengths outside the reach of conventional focal plane array detectors. However, the limited image quality and lengthy computational times for iterative reconstruction still impede the…
Single molecule spectroscopy aims at unveiling often hidden but potentially very important contributions of single entities to a system's ensemble response. Albeit contributing tremendously to our ever growing understanding of molecular…
In this two-part paper, we present a novel framework and methodology to analyze data from certain image-based biochemical assays, e.g., ELISPOT and Fluorospot assays. In this first part, we start by presenting a physical partial…
Many microscopy applications are limited by the total amount of usable light and are consequently challenged by the resulting levels of noise in the acquired images. This problem is often addressed via (supervised) deep learning based…
This paper is a review of recent mathematical and computational advances in optical tomography. We discuss the physical foundations of forward models for light propagation on microscopic, mesoscopic and macroscopic scales. We also consider…
Optical mixing experiments show the ability of amplifying a weak optical signal by superposing it with a stronger one. This principle has been demonstrated also for weak signals at the quantum level, down to a single photon. In the present…
Singlet fission has emerged as one of the most exciting phenomena known to improve the efficiencies of different types of solar cells and has found uses in diverse optoelectronic applications. The range of available singlet fission…
Recently, super-resolution ultrasound imaging with ultrasound localization microscopy (ULM) has received much attention. However, ULM relies on low concentrations of microbubbles in the blood vessels, ultimately resulting in long…
The advent of single molecule microscopy has revolutionized biological investigations by providing a powerful tool for the study of intercellular and intracellular trafficking processes of protein molecules which was not available before…
Single-molecule localization microscopy allows practitioners to locate and track labeled molecules in biological systems. When extracting diffusion coefficients from the resulting trajectories, it is common practice to perform a linear fit…
Fluorescence Correlation Spectroscopy (FCS) yields measurement parameters (number of molecules, diffusion time) that characterize the concentration and kinetics of fluorescent molecules within a supposedly known observation volume. Absolute…
Single molecule imaging is one of the main target areas of X-ray free electron lasers. It relies on the possibility of orienting the large number of low counting statistics 2D diffraction patterns taken at random orientations of identical…
Single molecule fluorescence microscopy is a powerful technique for uncovering detailed information about biological systems, both in vitro and in vivo. In such experiments, the inherently low signal to noise ratios mean that accurate…
Super-resolution is an important but difficult problem in image/video processing. If a video sequence or some training set other than the given low-resolution image is available, this kind of extra information can greatly aid in the…