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Circular dichroism (CD) induced by spin angular momentum of light is vital to investigate the chirality of microscopic objects such as molecules, proteins and metamaterials. However, orbital angular momentum (OAM) of light failed to…

We describe a new experimental setup for the detection of magnetic circular dichroism with fast electrons (EMCD). As compared to earlier findings the signal is an order of magnitude higher, while the probed area could be significantly…

We theoretically investigate light matter interactions for chiral molecules in the presence of non-chiral nanoantennas. Isotropic nanostructures supporting optical-frequency electric or magnetic dipoles are sufficient to locally enhance the…

Mesoscale and Nanoscale Physics · Physics 2013-06-14 Aitzol Garcia-Etxarri , Jennifer A. Dionne

Coherent diffraction imaging (CDI) allows the retrieval of the structure of an isolated object, such as a macromolecule, from its diffraction pattern. CDI requires the fulfilment of two conditions: the imaging radiation must be coherent and…

Optics · Physics 2018-11-16 Tatiana Latychevskaia , Hans-Werner Fink

We propose a chiral imaging modality based on optical chirality engineering, fluorescence-detected circular dichroism and structured illumination microscopy. In this method, the optical chirality of the illumination is structured and the…

Recent advancements in X-ray light sources at synchrotrons and X-ray free-electron lasers (XFELs) present exciting opportunities to probe molecular chirality using novel nonlinear spectroscopies with element-sensitivity. Circular dichroism…

Chemical Physics · Physics 2025-01-27 Yeonsig Nam , Majed Chergui , Linda Young , Jérémy R. Rouxel

In chemistry and biochemistry, chirality represents the structural asymmetry characterized by non-superimposable mirror images for a material like DNA. In physics, however, chirality commonly refers to the spin-momentum locking of a…

Materials Science · Physics 2024-08-07 Binghai Yan

In photoelectron circular dichroism (PECD) it is generally difficult to trace how and when the chirality of the molecule is imprinted onto the photoelectron. We present simulations of PECD in a simple model and employ chirality measures to…

Atomic Physics · Physics 2025-03-04 Marec W. Heger , Daniel M. Reich

We introduce meta-diastereomers, hybrid systems where molecular chirality ($\leq 10$\,nm) and nanoscale chirality ($>100$\,nm) combine to create a new hierarchical chiral state with emergent optical properties. By coupling chiral…

It is a standard exercise in mechanical engineering to infer the external forces and torques on a body from its static shape and known elastic properties. Here we apply this kind of analysis to distorted double-helical DNA in complexes with…

Biomolecules · Quantitative Biology 2009-11-13 Nils B. Becker , Ralf Everaers

We demonstrate electron magnetic linear dichroism as a quantitative probe of vectorial magnetic order parameters with nanometer resolution in transmission electron microscopy. Explicit inclusion of vectorial core-level exchange splitting…

Mesoscale and Nanoscale Physics · Physics 2026-05-28 Jan Hajduček , Jáchym Štindl , Ján Rusz , Vojtěch Uhlíř

Polarization-dependent photon spectroscopy (dichroism) using signal-enhancing superchiral beams is shown to be sensitive to magnetic properties of the sample, whereas previous investigations explored charge-like electronic properties of…

Materials Science · Physics 2019-03-06 S. W. Lovesey , J. T. Collins , S. P. Collins

We derive here a new highly selective photoelectron-based chirality-sensing technique that utilizes 'locally-chiral' laser pulses. We show that this approach results in strong chiral discrimination, where the standard forwards/backwards…

Chemical Physics · Physics 2021-07-14 Ofer Neufeld , Hannes Hübener , Angel Rubio , Umberto De Giovannini

We present a unique experimental design that enables the measurement of photoelectron circular dichroism (PECD) from chiral molecules in aqueous solution. The effect is revealed from the intensity difference of photoelectron emission into a…

Chirality is at the origin of life and is ubiquitous in nature. An object is deemed chiral if it is non-superimposable with its own mirror image. This relates to how circularly polarized light interacts with such object, a circular…

Electronic circular dichroism (ECD) spectroscopy captures the chiroptical response of molecules, enabling absolute configuration assignment that is vital for enantioselective synthesis and drug design. The practical use of ECD spectra in…

Quantum Physics · Physics 2026-02-04 Amandeep Singh Bhatia , Sabre Kais

Photoelectron circular dichroism (PECD) is a highly sensitive enantiospecific spectroscopy for studying chiral molecules in the gas phase using either single-photon ionization or multiphoton ionization. In the short pulse limit investigated…

Chiroptical effects using circularly polarized light produce signals that change sign when switching either molecular handedness (enantiosensitivity) or the light helicity (circular dichroism). Here, we break this…

Circular dichroism (CD) spectroscopy is a useful technique for characterizing chiral molecules. It is more sensitive than total absorption to molecule conformation, and it is routinely used to identify enantiomers. We present here a first…

Chemical Physics · Physics 2022-12-14 Elena Molteni , Giancarlo Cappellini , Davide Sangalli

Photoelectron circular dichroism (PECD) is a method whereby randomly oriented chiral molecules are irradiated by circularly-polarized light, photoionizing electrons, which are measured in a momentum-resolved manner. This scheme permits…

Chemical Physics · Physics 2025-05-23 Ofer Neufeld