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Deep, high-resolution imaging is essential for unraveling biological complexity and advancing medical diagnostics, yet scattering fundamentally limits optical methods. Among the most promising approaches, photoacoustic imaging achieves…

We present a new approach for spatiotemporal focusing through complex scattering media by wave front shaping. Using a nonlinear feedback signal to shape the incident pulsed wave front, we show that the limit of a spatiotemporal matched…

This thesis describes experimental work on the use of wavefront shaping to steer light through strongly scattering materials. We find that scattering does not irreversibly scramble the incident wave. By shaping the incident wavefront, we…

Optics · Physics 2008-07-08 I. M. Vellekoop

Light propagation in materials with microscopic inhomogeneities is affected by scattering. In scattering materials, such as powders, disordered metamaterials or biological tissue, multiple scattering on sub-wavelength particles makes light…

Disordered Systems and Neural Networks · Physics 2009-11-13 I. M. Vellekoop , A. P. Mosk

Wavefront shaping has revolutionized the concepts of optical imaging and focusing. Contrary to what was believed, strong scattering in the optical paths can be exploited in favor of light focusing through turbid media and ultimately improve…

Focusing light through dynamically varying heterogeneous media is a sought-after goal with important applications ranging from free-space communication to nano-surgery. The underlying challenge is to control the optical wavefront with a…

In turbid media, scattering of light scrambles information of the incident beam and represents an obstacle to optical imaging. Noninvasive imaging through opaque layers is challenging for dynamic and wide-field objects due to unreliable…

Optics · Physics 2018-10-17 Yuan Yuan , Hui Chen

Optical imaging through scattering media is a fundamental challenge in many applications. Recently, substantial breakthroughs such as imaging through biological tissues and looking around corners have been obtained by the use of…

Optics · Physics 2020-07-09 Tomer Yeminy , Ori Katz

Optical focusing at depths in tissue is the Holy Grail of biomedical optics that may bring revolutionary advancement to the field. Wavefront shaping is a widely accepted approach to solve this problem, but most implementations thus far have…

Applied Physics · Physics 2019-09-04 Yunqi Luo , Suxia Yan , Huanhao Li , Puxiang Lai , Yuanjin Zheng

Super-resolution imaging with advanced optical systems has been revolutionizing technical analysis in various fields from biological to physical sciences. However, many objects are hidden by strongly scattering media such as rough wall…

Optics · Physics 2021-09-06 Dong Wang , Sujit Kumar Sahoo , Cuong Dang

While scattered light conveys most of the information we perceive, scattering may also distort that information before it reaches our detectors. The problem is acute in many applications, such as in high-resolution microscopy of biological…

We experimentally demonstrate a non-imaging approach to displacement measurement for complex scattering materials. By spatially controlling the wave front of the light that incidents on the material we concentrate the scattered light in a…

Optics · Physics 2015-06-03 E. G. van Putten , A. Lagendijk , A. P. Mosk

Wavefront shaping allows focusing light through or inside strongly scattering media, but the background intensity also increases due to long-range correlations, reducing the target's contrast. By manipulating non-local intensity…

Despite the tremendous progresses in wavefront control through or inside complex scattering media, several limitations prevent reaching practical feasibility for nonlinear imaging in biological tissues. While the optimization of nonlinear…

Optics · Physics 2016-12-06 Hilton B. de Aguiar , Sylvain Gigan , Sophie Brasselet

The increasing complexity of neural networks and the energy consumption associated with training and inference create a need for alternative neuromorphic approaches, e.g. using optics. Current proposals and implementations rely on physical…

Optics · Physics 2023-08-31 Clara C. Wanjura , Florian Marquardt

Over the past decade, optical wavefront shaping has been developed to focus light through highly opaque scattering layers, opening new possibilities for biomedical applications. To probe light intensity deep inside soft scattering media…

Optics · Physics 2025-08-25 Fei Xia , Ivo Leite , Robert Prevedel , Thomas Chaigne

Wavefront shaping makes it possible to form a focus through opaque scattering materials. In some cases, this focus may be scanned over a small distance using the optical memory effect. However, in many cases of interest, the optical memory…

Optics · Physics 2020-01-08 Bahareh Mastiani , Tzu-Lun Ohn , Ivo M. Vellekoop

We present an optical wavefront shaping approach that allows tracking and localization of signal hidden inside or behind a scattering medium. The method combines traditional feedback based wavefront shaping together with a switch function,…

Scattering hinders the passage of light through random media and consequently limits the usefulness of optical techniques for sensing and imaging. Thus, methods for increasing the transmission of light through such random media are of…

Optics · Physics 2014-06-23 Curtis Jin , Raj Rao Nadakuditi , Eric Michielssen , Stephen Rand

Optical-resolution fluorescence imaging through and within complex samples presents a significant challenge due to random light scattering, with substantial implications across multiple fields. While significant advancements in coherent…

Optics · Physics 2023-12-27 Gil Weinberg , Elad Sunray , Ori Katz