Related papers: GEANT4 simulation of a new range verification meth…
We present {\gamma} spectroscopy validation measurements for the Geant4 radioactive decay simulation for a selected range of isotopes using a simple experimental setup. Using these results we point out problems in the decay simulation and…
Given the sensitivity of proton therapy to anatomical variations, this cancer treatment modality is expected to benefit greatly from integration with magnetic resonance (MR) imaging. One of the obstacles hindering such an integration are…
The Fast Dose Calculator (FDC), a track repeating algorithm Monte Carlo method was initially developed for proton therapy. The validation for proton therapy has been demonstrated in a previous work. This method can be expanded to ion…
Charged particle beams are used in Particle Therapy (PT) to treat oncological patients due to their selective dose deposition in tissues and to their high biological effect in killing cancer cells with respect to photons and electrons used…
The use of contrast agents has previously been proposed as a novel method to increase the activation close to the Bragg peak, aiming to improve the quality of proton range monitoring in vivo. In a recent work, we demonstrated the…
A major part of cosmic rays consists of the primary protons, and this portion plays a crucial role in the space applications such as shielding of spacecrafts. In this study, the proton flux values measured at the top of the atmosphere…
The performance of the energy degrader in terms of beam properties directly impacts the design and cost of cyclotron-based proton therapy centers. The aim of this study is to evaluate the performances of different existing and novel…
Objective: To assess the accuracy and computational performance of a stochastic differential equation (SDE)--based model for proton beam dose calculation by benchmarking against Geant4 in simplified phantom geometries. Approach: Building on…
The interplay between the beam delivery time structure and the patient motion makes 4D dose calculation (4DDC) important when treating moving tumors with intensity modulated proton therapy. 4DDC based on phase sorting of a 4DCT suffers from…
External beam X-ray therapy (XRT) and proton therapy (PT) are effective and widely accepted forms of treatment for many types of cancer. However, the procedures require extensive computerized planning. Current planning systems for both XRT…
Fast procedures for the beam quality assessment and for the monitoring of beam energy modulations during the irradiation are among the most urgent improvements in particle therapy. Indeed, the online measurement of the particle beam energy…
The simulation of radioactive decays is a common task in Monte-Carlo systems such as Geant4. Usually, a system either uses an approach focusing on the simulations of every individual decay or an approach which simulates a large number of…
Low background gamma spectrometry employing HPGe detectors is a sensitive technique for measuring low-level radioactivity in environmental applications, material screening, and for rare decay searches. This work presents spectroscopic…
This study presents a proof-of-concept for a novel Bayesian inverse method in a one-dimensional setting, aimed at proton beam therapy treatment verification. Our methodology is predicated on a hypothetical scenario wherein strategically…
Depth distributions of positron-emitting nuclei in PMMA phantoms are calculated within a Monte Carlo model for Heavy-Ion Therapy (MCHIT) based on the GEANT4 toolkit (version 8.0). The calculated total production rates of $^{11}$C, $^{10}$C…
The Miniaturized Detector for Application in Space (MIDAS) is a compact device with dimensions 5 x 5 x 1 cm3 which combines position sensitive Si detectors and a fast neutrons spectrometer. MIDAS is developed with purpose to act as a linear…
Heavy-ion therapy, particularly using scanned (active) beam delivery, provides a precise and highly conformal dose distribution, with maximum dose deposition for each pencil beam at its endpoint (Bragg peak), and low entrance and exit dose.…
We describe a physics simulation software framework, MAGE, that is based on the GEANT4 simulation toolkit. MAGE is used to simulate the response of ultra-low radioactive background radiation detectors to ionizing radiation, specifically the…
We recently proposed a new approach for the real-time monitoring of particle therapy treatments with the goal of achieving high sensitivities on the particle range measurement already at limited counting statistics. This method extends the…
Purpose: To measure dispersion of a clinical proton therapy beam. Methods and Materials: The proton center at our institution uses a Hitachi PROBEAT V synchrotron that delivers beams with energies ranging from 70 to 230 MeV to five…