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In this work, we proposed virtual imaging simulators as an alternative approach to experimental validation of beam range uncertainty in complex patient geometry using a computational model of a human head and a photon-counting CT scanner.…

Medical Physics · Physics 2026-01-05 S. Vrbaški , G. Stanić , S. Molinelli , M. Bhattarai , E. Abadi , M. Ciocca , E. Samei

A radiographic setup for an investigation of fast dynamic processes with areal density of targets up to 5 g/cm$^2$ is under development on the basis of high-current proton linear accelerator at the Institute for Nuclear Research (Troitsk,…

In proton therapy both the energy, which determines the range, and the distal slope, which reflects the rate at which the protons decelerate, are of import if we are to ensure accurate dose deposition and maximum tissue sparing. This…

Medical Physics · Physics 2020-11-03 Tim Fulcher , Richard A Amos , Hywel Owen , Rob Edgecock

The measurement of the beta asymmetry parameter in nuclear beta decay is a potentially very sensitive tool to search for non V-A components in the charge-changing weak interaction. To reach the required precision (percent level) all effects…

Intensity modulated proton therapy (IMPT) is an advanced cancer treatment modality that offers significant advantages over conventional X-ray therapies, particularly in its ability to minimize radiation dose beyond the tumor target. This…

Medical Physics · Physics 2025-08-06 Hunter D. Ellis , Imteaz Rahaman , Apostoli Hillas , Botong Li , Vikren Sarkar , Kai Fu

Treating cancer is one of the most challenging task in medical sciences. Only limited types of cancer treatments are available as their study is still ongoing. The earlier therapies like radiotherapy with x-rays, chemotherapy are associated…

Accelerator Physics · Physics 2024-06-06 R. Kanishka

Enhanced-accuracy ion-range verification in real time shall enable a significant step forward in the use of therapeutic ion beams. Positron-emission tomography (PET) and prompt-gamma imaging (PGI) are two of the most promising and…

Proton therapy is a cancer treatment technique currently in growth worldwide. It offers advantages with respect to conventional X-ray and $\gamma$-ray radiotherapy, in particular, a better control of the dose deposition allowing to reach a…

Monte Carlo simulations have been performed in order to evaluate the efficiencies of several light ions identification techniques. The detection system was composed with layers of scintillating material to measure either the deposited…

Nuclear Experiment · Physics 2013-10-02 S. Salvador , M. Labalme , J. M. Fontbonne , J. Dudouet , J. Colin , D. Cussol

Objective: Real-time adaptive proton range verification systems based on produced neutrons require accurate information on their non-isotropic momentum distributions within short times, for which Monte Carlo (MC) methods are too…

Objective: Proton therapy is a precision-focused cancer treatment where accurate proton beam range monitoring is critical to ensure effective dose delivery. This can be achieved by prompt gamma detection with a Compton camera like the…

We are currently conceiving, through (MC) simulation, a multi-channel gamma detector array (TIARA for Time-of-flight Imaging ARrAy) for the online monitoring of protontherapy treatments. By measuring the Time-Of-Flight (TOF) between a beam…

Radiotherapy is one of the main methods in the successful treatment of cancer. The tumor is irradiated with photons or charged particles (e.g. protons), and in the case of massive charged particles, the treatment results in less unnecessary…

Medical Physics · Physics 2019-03-20 Monika Varga-Kofarago

Computer tomography is one of the most promising new methods to image abnormal tissues inside the human body. Tomography is also used to position the patient accurately before radiation therapy. Hadron therapy for treating cancer has become…

Nowadays, the current threat of international terrorism is set to a severe level, demanding worldwide enhanced security. Radioactive materials that could be fashioned into a radiation dispersal device typically emit gamma rays, while…

Instrumentation and Detectors · Physics 2017-11-16 A. Sh. Georgadze

Background and purpose: In-beam Positron Emission Tomography (PET) is one of the modalities that can be used for in-vivo non-invasive treatment monitoring in proton therapy. PET distributions obtained during various treatment sessions can…

Possibilities of discriminating neutrons and gamma rays in the AGATA gamma-ray tracking spectrometer have been investigated with the aim of reducing the background due to inelastic scattering of neutrons in the high-purity germanium…

Nuclear Experiment · Physics 2009-09-09 A. Ataç , A. Kaşkaş , S. Akkoyun , M. Şenyiğit , T. Hüyük , S. O. Kara , J. Nyberg

A version of Geant4 has been developed to treat high-energy proton radiography. This article presents the results of calculations simulating the effects of nuclear elastic scattering for various test step wedges. Comparisons with…

Instrumentation and Detectors · Physics 2014-09-19 Xu Haibo , Zheng Na

Novel radiotherapy techniques like synchrotron X-ray microbeam radiation therapy (MRT), require fast dose distribution predictions that are accurate at the sub-mm level, especially close to tissue/bone/air interfaces. Monte Carlo physics…

The paper discusses some 3D simulations to compute the ionizing radiation dose during laser-plasma experiments leading to the generation of accelerated protons and electrons. Also, we suggest a new method to increase the measurement…

Instrumentation and Detectors · Physics 2019-10-02 M. Ganciu , A. Chirosca , A. Groza , E. Stancu , O. Stoican , D. B. Dreghici , B. Butoi , C. Ticos , B. Mihalcea , B. Cramariuc