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Tissue microarray (TMA) images have been used increasingly often in cancer studies and the validation of biomarkers. TACOMA---a cutting-edge automatic scoring algorithm for TMA images---is comparable to pathologists in terms of accuracy and…

Computer Vision and Pattern Recognition · Computer Science 2018-12-04 Donghui Yan , Timothy W. Randolph , Jian Zou , Peng Gong

Cancer research is increasingly driven by the integration of diverse data modalities, spanning from genomics and proteomics to imaging and clinical factors. However, extracting actionable insights from these vast and heterogeneous datasets…

Glioblastoma Multiforme (GBM) is a malignant brain cancer forming around 48% of al brain and Central Nervous System (CNS) cancers. It is estimated that annually over 13,000 deaths occur in the US due to GBM, making it crucial to have early…

Image and Video Processing · Electrical Eng. & Systems 2022-01-28 Sauman Das

Melanoma detection is vital for early diagnosis and effective treatment. While deep learning models on dermoscopic images have shown promise, they require specialized equipment, limiting their use in broader clinical settings. This study…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Volodymyr Sydorskyi , Igor Krashenyi , Oleksii Yakubenko

Cancer is a complex disease that provides various types of information depending on the scale of observation. While most tumor diagnostics are performed by observing histopathological slides, radiology images should yield additional…

Image and Video Processing · Electrical Eng. & Systems 2020-10-07 Marvin Lerousseau , Eric Deutsh , Nikos Paragios

Magnetic resonance images (MRI) play an important role in supporting and substituting clinical information in the diagnosis of multiple sclerosis (MS) disease by presenting lesion in brain MR images. In this paper, an algorithm for MS…

Image and Video Processing · Electrical Eng. & Systems 2018-04-11 Saba Heidari Gheshlaghi , Abolfazl Madani , AmirAbolfazl Suratgar , Fardin Faraji

Timely brain tumor diagnosis remains challenging in low-resource clinical environments where expert neuroradiology interpretation, high-end MRI hardware, and invasive biopsy procedures may be limited. Although deep learning has achieved…

Image and Video Processing · Electrical Eng. & Systems 2025-12-30 Areeb Ehsan

Quantum Machine Learning (QML) is a red-hot field that brings novel discoveries and exciting opportunities to resolve, speed up, or refine the analysis of a wide range of computational problems. In the realm of biomedical research and…

Machine Learning · Computer Science 2024-10-04 Mandeep Kaur Saggi , Amandeep Singh Bhatia , Mensah Isaiah , Humaira Gowher , Sabre Kais

In oncology, recurrence after treatment is one of the major challenges, related to patients' survival and quality of life. Conventionally, prediction of cancer relapse has always relied on clinical observation with statistical model…

Machine Learning · Computer Science 2025-02-25 Muhammad Umer Qayyum , Muhammad Fahad , Nasrullah Abbasi

The advent of large scale, high-throughput genomic screening has introduced a wide range of tests for diagnostic purposes. Prominent among them are tests using miRNA expression levels. Genomics and proteomics now provide expression levels…

Genomics · Quantitative Biology 2016-11-08 Neerja Garikipati

Gliomas are brain tumours with a high mortality rate. There are various grades and sub-types of this tumour, and the treatment procedure varies accordingly. Clinicians and oncologists diagnose and categorise these tumours based on visual…

Image and Video Processing · Electrical Eng. & Systems 2020-11-12 Azam Hamidinekoo , Tomasz Pieciak , Maryam Afzali , Otar Akanyeti , Yinyin Yuan

Microsatellite instability (MSI) is associated with several tumor types and its status has become increasingly vital in guiding patient treatment decisions. However, in clinical practice, distinguishing MSI from its counterpart is…

Machine Learning · Statistics 2020-10-08 Jin Zhu , Wangwei Wu , Yuting Zhang , Shiyun Lin , Yukang Jiang , Ruixian Liu , Xueqin Wang

Glioblastoma is a common brain malignancy that tends to occur in older adults and is almost always lethal. The effectiveness of chemotherapy, being the standard treatment for most cancer types, can be improved if a particular genetic…

Image and Video Processing · Electrical Eng. & Systems 2022-03-01 Numan Saeed , Shahad Hardan , Kudaibergen Abutalip , Mohammad Yaqub

Cervical cancer threatens the health of women seriously. Radiotherapy is one of the main therapy methods but with high risk of acute hematologic toxicity. Delineating the bone marrow (BM) for sparing using computer tomography (CT) images to…

Image and Video Processing · Electrical Eng. & Systems 2022-04-21 Yuening Wang , Ying Sun , Jie Yuan , Kexin Gan , Hanzi Xu , Han Gao , Xiuming Zhang

Patients with metastatic breast cancer (mBC) undergo repeated computed tomography (CT) imaging during treatment to monitor disease progression. Accurate longitudinal tracking of individual lesions across scans from multiple radiologists is…

This paper deals with the multiple annotation problem in medical application of cancer detection in digital images. The main assumption is that though images are labeled by many experts, the number of images read by the same expert is not…

Computer Vision and Pattern Recognition · Computer Science 2014-12-10 Inna Stainvas , Alexandra Manevitch , Isaac Leichter

Background: The reproducibility of machine-learning models in prostate cancer detection across different MRI vendors remains a significant challenge. Methods: This study investigates Support Vector Machines (SVM) and Random Forest (RF)…

Background: This study aimed to predict lesion-specific outcomes after stereotactic radiotherapy (SRT) in patients with brain metastases from malignant melanoma (MBM), using clinical, dosimetric, and pretherapeutic MRI data. Methods: In…

The past years have seen a considerable increase in cancer cases. However, a cancer diagnosis is often complex and depends on the types of images provided for analysis. It requires highly skilled practitioners but is often time-consuming…

Image and Video Processing · Electrical Eng. & Systems 2022-10-24 Solene Bechelli

In this chapter we illustrate the use of some Machine Learning techniques in the context of omics data. More precisely, we review and evaluate the use of Random Forest and Penalized Multinomial Logistic Regression for integrative analysis…

Genomics · Quantitative Biology 2024-02-09 Aida Calviño , Almudena Moreno-Ribera , Silvia Pineda