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Efficiently acquired and precisely reconstructed imaging are crucial to the success of modern radiation therapy (RT). Computed tomography (CT) and magnetic resonance imaging (MRI) are two common modalities for providing RT treatment…

Image and Video Processing · Electrical Eng. & Systems 2025-04-15 Di Xu

Radiomic models have been shown to outperform clinical data for outcome prediction in glioblastoma (GBM). However, clinical implementation is limited by lack of parameters standardization. We aimed to compare nine machine learning…

The accurate classification of lymphoma subtypes using hematoxylin and eosin (H&E)-stained tissue is complicated by the wide range of morphological features these cancers can exhibit. We present LymphoML - an interpretable machine learning…

Glioma, a prevalent and heterogeneous tumor originating from the glial cells, can be differentiated as Low Grade Glioma (LGG) and High Grade Glioma (HGG) according to World Health Organization's norms. Classifying gliomas is essential for…

Computer Vision and Pattern Recognition · Computer Science 2025-03-03 Kiranmayee Janardhan , Christy Bobby Thomas

The field of medical imaging is an essential aspect of the medical sciences, involving various forms of radiation to capture images of the internal tissues and organs of the body. These images provide vital information for clinical…

Artificial Intelligence · Computer Science 2023-06-21 Shuvra Sarker , Angona Biswas , MD Abdullah Al Nasim , Md Shahin Ali , Sai Puppala , Sajedul Talukder

Background and Purpose: Radiomics features are used to identify disease types and predict therapy outcomes. However, how the radiomics features are different among different anatomical structures has never been investigated. Hence, we…

Quantitative Methods · Quantitative Biology 2022-05-18 Yoichi Watanabe , A. Biswas , K. Rangarajan , G. Rath , N. Gopishankar

Radiomics is a relatively new field which utilises automatically identified features from radiological scans. It has found a widespread application, particularly in oncology because many of the important oncological biomarkers are not…

Quantitative Methods · Quantitative Biology 2024-09-26 Stanislav Kozák

Medical imaging technologies have undergone extensive development, enabling non-invasive visualization of clinical information. The traditional review of medical images by clinicians remains subjective, time-consuming, and prone to human…

Image and Video Processing · Electrical Eng. & Systems 2024-07-22 Elizaveta Lavrova , Henry C. Woodruff , Hamza Khan , Eric Salmon , Philippe Lambin , Christophe Phillips

Background: We aim to develop enriched radiomics features that integrate classical structural radiomics with novel functional radiomics derived from liver MRI for diagnosis and risk stratification in liver cancer. The proposed framework…

In advancing discrete-based computational cancer models towards clinical applications, one faces the dilemma of how to deal with an ever growing amount of biomedical data that ought to be incorporated eventually in one form or another.…

Cell Behavior · Quantitative Biology 2008-06-26 Le Zhang , L. Leon Chen , Thomas S. Deisboeck

Genetic studies have identified associations between gene mutations and clear cell renal cell carcinoma (ccRCC). Because the complete gene mutational landscape cannot be characterized through biopsy and sequencing assays for each patient,…

The diagnosis of brain cancer relies heavily on medical imaging techniques, with MRI being the most commonly used. It is necessary to perform automatic segmentation of brain tumors on MRI images. This project intends to build an MRI…

Image and Video Processing · Electrical Eng. & Systems 2024-06-28 Yuxiang Hu , Haowei Yang , Ting Xu , Shuyao He , Jiajie Yuan , Haozhang Deng

Patients with metastatic breast cancer (mBC) undergo continuous medical imaging during treatment, making accurate lesion detection and monitoring over time critical for clinical decisions. Predicting drug response from post-treatment data…

Image and Video Processing · Electrical Eng. & Systems 2025-01-22 Subrata Mukherjee

Early cancer detection remains one of the most critical challenges in modern healthcare, where delayed diagnosis significantly reduces survival outcomes. Recent advancements in artificial intelligence, particularly deep learning, have…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Emmanuella Avwerosuoghene Oghenekaro

Multiple Sclerosis (MS) is a chronic autoimmune disease that can significantly reduce the quality of life of a patient. Existing treatment options can only help slow down the progression of the disease. Therefore, early detection and…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Abdul Basit , Ashir Rashid , Muhammad Abdullah Hanif , Muhammad Shafique

Purpose; The purpose of this study is to classify glial tumors into grade II, III and IV categories noninvasively by application of machine learning to multi-modal MRI features in comparison with volumetric analysis. Methods; We…

Image and Video Processing · Electrical Eng. & Systems 2022-08-16 Sevcan Turk , Kaya Oguz , Mehmet Orman , Emre Caliskan , Yesim Ertan , Erkin Ozgiray , Taner Akalin , Ashok Srinivasan , Omer Kitis

Cancer is a leading cause of death in many countries. An early diagnosis of cancer based on biomedical imaging ensures effective treatment and a better prognosis. However, biomedical imaging presents challenges to both clinical institutions…

Computer Vision and Pattern Recognition · Computer Science 2023-01-24 Hosein Barzekar , Yash Patel , Ling Tong , Zeyun Yu

The interactions between tumor cells and the tumor microenvironment (TME) dictate therapeutic efficacy of radiation and many systemic therapies in breast cancer. However, to date, there is not a widely available method to reproducibly…

Integrating cross-department multi-modal data (e.g., radiological, pathological, genomic, and clinical data) is ubiquitous in brain cancer diagnosis and survival prediction. To date, such an integration is typically conducted by human…

Machine Learning · Computer Science 2022-07-20 Can Cui , Han Liu , Quan Liu , Ruining Deng , Zuhayr Asad , Yaohong WangShilin Zhao , Haichun Yang , Bennett A. Landman , Yuankai Huo

Thyroid cancer is common worldwide, with a rapid increase in prevalence across North America in recent years. While most patients present with palpable nodules through physical examination, a large number of small and medium-sized nodules…

Image and Video Processing · Electrical Eng. & Systems 2020-06-11 Fatemeh Abdolali , Atefeh Shahroudnejad , Abhilash Rakkunedeth Hareendranathan , Jacob L Jaremko , Michelle Noga , Kumaradevan Punithakumar