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It is known that evolution strategies in continuous domains might not converge in the presence of noise. It is also known that, under mild assumptions, and using an increasing number of resamplings, one can mitigate the effect of additive…

Optimization and Control · Mathematics 2014-04-10 Marie-Liesse Cauwet

A major hindrance to studies of microbial diversity has been that the vast majority of microbes cannot be cultured in the laboratory and thus are not amenable to traditional methods of characterization. Environmental shotgun sequencing…

Genomics · Quantitative Biology 2007-08-24 Sourav Chatterji , Ichitaro Yamazaki , Zhaojun Bai , Jonathan Eisen

Emerging sonography techniques often require increasing the number of transducer elements involved in the imaging process. Consequently, larger amounts of data must be acquired and processed. The significant growth in the amounts of data…

Information Theory · Computer Science 2015-06-04 Noam Wagner , Yonina C. Eldar , Zvi Friedman

The inverse design of metasurfaces faces inherent challenges due to the nonlinear and highly complex relationship between geometric configurations and their electromagnetic behavior. Traditional optimization approaches often suffer from…

Intuitively, if a density operator has small rank, then it should be easier to estimate from experimental data, since in this case only a few eigenvectors need to be learned. We prove two complementary results that confirm this intuition.…

Quantum Physics · Physics 2012-10-18 Steven T. Flammia , David Gross , Yi-Kai Liu , Jens Eisert

This paper proposes a sparse Bayesian treatment of deep neural networks (DNNs) for system identification. Although DNNs show impressive approximation ability in various fields, several challenges still exist for system identification…

Systems and Control · Electrical Eng. & Systems 2022-06-02 Hongpeng Zhou , Chahine Ibrahim , Wei Xing Zheng , Wei Pan

Gene expression profiles obtained through DNA microarray have proven successful in providing critical information for cancer detection classifiers. However, the limited number of samples in these datasets poses a challenge to employ complex…

Machine Learning · Computer Science 2024-08-20 Arya Hadizadeh Moghaddam , Mohsen Nayebi Kerdabadi , Cuncong Zhong , Zijun Yao

Telehealth and wearable equipment can deliver personal healthcare and necessary treatment remotely. One major challenge is transmitting large amount of biosignals through wireless networks. The limited battery life calls for low-power data…

Information Theory · Computer Science 2013-11-19 Benyuan Liu , Zhilin Zhang , Hongqi Fan , Qiang Fu

Metagenomic studies have primarily relied on de novo assembly for reconstructing genes and genomes from microbial mixtures. While reference-guided approaches have been employed in the assembly of single organisms, they have not been used in…

Compressed sensing is a signal processing technique that allows for the reconstruction of a signal from a small set of measurements. The key idea behind compressed sensing is that many real-world signals are inherently sparse, meaning that…

Machine Learning · Computer Science 2025-09-16 Shane Stevenson , Maryam Sabagh

Minimizers are sampling schemes with numerous applications in computational biology. Assuming a fixed alphabet of size $\sigma$, a minimizer is defined by two integers $k,w\ge2$ and a linear order $\rho$ on strings of length $k$ (also…

Data Structures and Algorithms · Computer Science 2025-06-06 Arseny Shur

We develop approximation algorithms for set-selection problems with deterministic constraints, but random objective values, i.e., stochastic probing problems. When the goal is to maximize the objective, approximation algorithms for probing…

Data Structures and Algorithms · Computer Science 2021-11-04 Weina Wang , Anupam Gupta , Jalani Williams

Compressed sensing is a powerful tool in applications such as magnetic resonance imaging (MRI). It enables accurate recovery of images from highly undersampled measurements by exploiting the sparsity of the images or image patches in a…

Machine Learning · Statistics 2016-10-04 Saiprasad Ravishankar , Yoram Bresler

Sparse wideband sensor array design for sensor location optimisation is highly nonlinear and it is traditionally solved by genetic algorithms, simulated annealing or other similar optimization methods. However, this is an extremely…

Information Theory · Computer Science 2014-03-20 Matthew B. Hawes , Wei Liu

We present a weakly supervised deep learning method to perform instance segmentation of cells present in microscopy images. Annotation of biomedical images in the lab can be scarce, incomplete, and inaccurate. This is of concern when…

Computer Vision and Pattern Recognition · Computer Science 2019-08-28 Fidel A. Guerrero-Peña , Pedro D. Marrero Fernandez , Tsang Ing Ren , Alexandre Cunha

Bayesian coresets have emerged as a promising approach for implementing scalable Bayesian inference. The Bayesian coreset problem involves selecting a (weighted) subset of the data samples, such that the posterior inference using the…

Machine Learning · Statistics 2021-03-01 Jacky Y. Zhang , Rajiv Khanna , Anastasios Kyrillidis , Oluwasanmi Koyejo

We describe different Bayesian ensemble refinement methods, examine their interrelation, and discuss their practical application. With ensemble refinement, the properties of dynamic and partially disordered (bio)molecular structures can be…

Data Analysis, Statistics and Probability · Physics 2016-01-20 Gerhard Hummer , Jürgen Köfinger

Federated learning is a privacy-preserving approach to train a global model at a central server by collaborating with wireless devices, each with its own local training data set. In this paper, we present a compressive sensing approach for…

Signal Processing · Electrical Eng. & Systems 2020-08-06 Yo-Seb Jeon , Mohammad Mohammadi Amiri , Jun Li , H. Vincent Poor

Microbiome data analysis is essential for understanding host health and disease, yet its inherent sparsity and noise pose major challenges for accurate imputation, hindering downstream tasks such as biomarker discovery. Existing imputation…

Machine Learning · Computer Science 2025-08-01 Rabeya Tus Sadia , Qiang Cheng

Symmetry principles play an important role in geometry, and physics, allowing for the reduction of complicated systems to simpler, more comprehensible models that preserve the system's features of interest. Biological systems are often…

Cell Behavior · Quantitative Biology 2025-02-26 Luis A. Álvarez-García , Wolfram Liebermeister , Ian Leifer , Hernán A. Makse
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