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Testing for Hardy-Weinberg equilibrium (HWE) is a fundamental component of genetic data analysis, widely used for quality control and model validation. Although HWE testing is well established for autosomal loci, inference on the X…

Applications · Statistics 2026-05-20 Lin Zhang , Andrew Paterson , Lei Sun

We derive asymptotic expansions up to order $n^{-1/2}$ for the nonnull distribution functions of the likelihood ratio, Wald, score and gradient test statistics in the class of dispersion models, under a sequence of Pitman alternatives. The…

Statistics Theory · Mathematics 2011-02-23 Artur J. Lemonte , Silvia L. P. Ferrari

We study methods for identifying heterogeneous parameter components in distributed M-estimation with minimal data transmission. One is based on a re-normalized Wald test, which is shown to be consistent as long as the number of distributed…

Machine Learning · Statistics 2025-06-26 Zelin Xiao , Jia Gu , Song Xi Chen

Adaptive randomized experiments update treatment probabilities as data accrue, but still require an end-of-study interval for the average treatment effect (ATE) at a prespecified horizon. Under adaptive assignment, propensities can keep…

Methodology · Statistics 2026-02-18 Gabriel Saco

Testing heteroscedasticity of the errors is a major challenge in high-dimensional regressions where the number of covariates is large compared to the sample size. Traditional procedures such as the White and the Breusch-Pagan tests…

Methodology · Statistics 2017-10-16 Zhaoyuan Li , Jianfeng Yao

Non-compliance is common in real world experiments. We focus on inference about the sample complier average causal effect, that is, the average treatment effect for experimental units who are compliers. We present three types of inference…

Methodology · Statistics 2023-10-05 Zhen Zhong , Per Johansson , Junni L. Zhang

The beyond-Horndeski gravity has recently been reformulated in the dark energy paradigm - which has been dubbed, Unified Dark Energy (UDE). The evolution equations for the given UDE appear to correspond to a non-conservative dark energy…

Cosmology and Nongalactic Astrophysics · Physics 2020-01-15 Didam Duniya , Teboho Moloi , Chris Clarkson , Julien Larena , Roy Maartens , Bishop Mongwane , Amanda Weltman

Nonparametric generalized likelihood ratio test is popularly used for model checking for regressions. However, there are two issues that may be the barriers for its powerfulness. First, the bias term in its liming null distribution causes…

Methodology · Statistics 2015-07-23 Cuizhen Niu , Xu Guo , Lixing Zhu

Wald-type tests are convenient because they allow one to test a wide array of linear and nonlinear restrictions from a single unrestricted estimator; we focus on the problem of implementing Wald-type tests for nonlinear restrictions. We…

Statistics Theory · Mathematics 2013-12-03 Jean-Marie Dufour , Eric Renault , Victoria Zinde-Walsh

In this expository note we describe a surprising phenomenon in overparameterized linear regression, where the dimension exceeds the number of samples: there is a regime where the test risk of the estimator found by gradient descent…

Machine Learning · Statistics 2019-12-17 Preetum Nakkiran

For many causal effect parameters of interest, doubly robust machine learning (DRML) estimators $\hat{\psi}_{1}$ are the state-of-the-art, incorporating the good prediction performance of machine learning; the decreased bias of doubly…

Machine Learning · Statistics 2020-07-14 Lin Liu , Rajarshi Mukherjee , James M. Robins

Data subject to heavy-tailed errors are commonly encountered in various scientific fields, especially in the modern era with explosion of massive data. To address this problem, procedures based on quantile regression and Least Absolute…

Statistics Theory · Mathematics 2014-10-09 Jianqing Fan , Quefeng Li , Yuyan Wang

A central goal of causal inference is to detect and estimate the treatment effects of a given treatment or intervention on an outcome variable of interest, where a member known as the heterogeneous treatment effect (HTE) is of growing…

Statistics Theory · Mathematics 2020-10-27 Zijun Gao , Yanjun Han

We develop joint confidence regions for linear regression coefficients when the regressors and errors are jointly stationary and ergodic with unspecified serial dependence. The method applies random smoothing, using an independent auxiliary…

Methodology · Statistics 2026-05-21 Mous-Abou Hamadou , Martial Longla , Mathias Nthiani Muia , Mahmud Hasan

The objective of this paper is to develop statistical methodology for planning and evaluating three-armed non-inferiority trials for general retention of effect hypotheses, where the endpoint of interest may follow any (regular) parametric…

Methodology · Statistics 2009-12-22 M. Mielke , A. Munk

We generalise the inference procedure for eigenvectors of symmetrizable matrices of Tyler (1981) to that of invariant and singular subspaces of non-diagonalizable matrices. Wald tests for invariant vectors and $t$-tests for their individual…

Statistics Theory · Mathematics 2025-10-13 Jérôme R. Simons

High-dimensional vector autoregression with measurement error is frequently encountered in a large variety of scientific and business applications. In this article, we study statistical inference of the transition matrix under this model.…

Methodology · Statistics 2020-09-18 Xiang Lyu , Jian Kang , Lexin Li

In this paper new test statistics are introduced and studied for the important problem of testing hypothesis that involves inequality constraint on proportions when the sample comes from independent binomial random variables: Wald type and…

Methodology · Statistics 2014-02-28 Nirian Martín , Raquel Mata , Leando Pardo

Robust design is one of the main tools employed by engineers for the facilitation of the design of high-quality processes. However, most real-world processes invariably contend with external uncontrollable factors, often denoted as outliers…

Methodology · Statistics 2023-09-12 Xuehong Gao , Zhijin Chen , Bosung Kim , Chanseok Park

A fundamental functional in nonparametric statistics is the Mann-Whitney functional ${\theta} = P (X < Y )$ , which constitutes the basis for the most popular nonparametric procedures. The functional ${\theta}$ measures a location or…

Methodology · Statistics 2023-11-30 Jonas Beck , Patrick B. Langthaler , Arne C. Bathke