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Real-time fMRI neurofeedback (rtfMRI-nf) is an emerging approach for studies and novel treatments of major depressive disorder (MDD). EEG performed simultaneously with an rtfMRI-nf procedure allows an independent evaluation of rtfMRI-nf…

Neurobiological and neurodegenerative diseases are inherently multifactorial, arising from coupled influences spanning genetic susceptibility, brain alterations, and environmental and behavioral factors. Multimodal modeling has therefore…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Shaowen Wan , Yanjun Lv , Lu Zhang , Dajiang Zhu , Bharat Biswal , Tianming Liu , Xiaobo Li , Lin Zhao

Depression is a major mental health condition that severely impacts the emotional and physical well-being of individuals. The simple nature of data collection from social media platforms has attracted significant interest in properly…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Md Rezwanul Haque , Md. Milon Islam , S M Taslim Uddin Raju , Hamdi Altaheri , Lobna Nassar , Fakhri Karray

Assessment of mental workload in real-world conditions is key to ensure the performance of workers executing tasks that demand sustained attention. Previous literature has employed electroencephalography (EEG) to this end despite having…

Machine Learning · Computer Science 2024-10-30 Isabela Albuquerque , João Monteiro , Olivier Rosanne , Abhishek Tiwari , Jean-François Gagnon , Tiago H. Falk

High temporal resolution measurements of human brain activity can be performed by recording the electric potentials on the scalp surface (electroencephalography, EEG), or by recording the magnetic fields near the surface of the head…

Data Analysis, Statistics and Probability · Physics 2015-01-22 Kevin H. Knuth

We seek to elucidate the impact of social activity, physical activity and functional health status (factors) on depressive symptoms (outcome) in the China Health and Retirement Longitudinal Study (CHARLS), a multi-year study of aging…

Applications · Statistics 2019-12-06 Yazhuo Deng , David R. Paul , Audrey Q. Fu

Epileptic seizure detection from EEG signals remains challenging due to the high dimensionality and nonlinear, potentially stochastic, dynamics of neural activity. In this work, we investigate whether features derived from topological data…

Machine Learning · Computer Science 2026-04-15 Sunia Tanweer , Narayan Puthanmadam Subramaniyam , Firas A. Khasawneh

As the development of measuring instruments and computers has accelerated the collection of massive amounts of data, functional data analysis (FDA) has experienced a surge of attention. The FDA methodology treats longitudinal data as a set…

Methodology · Statistics 2024-07-09 Tomoya Wakayama , Hidetoshi Matsui

Bipolar Disorder (BD) is a psychiatric condition diagnosed by repetitive cycles of hypomania and depression. Since diagnosing BD relies on subjective behavioral assessments over a long period, a solid diagnosis based on objective criteria…

Image and Video Processing · Electrical Eng. & Systems 2023-10-12 Masood Hamed Saghayan , Mohammad Hossein Zolfagharnasab , Ali Khadem , Farzam Matinfar , Hassan Rashidi

Depression commonly co-occurs with neurodegenerative disorders like Multiple Sclerosis (MS), yet the potential of speech-based Artificial Intelligence for detecting depression in such contexts remains unexplored. This study examines the…

Computation and Language · Computer Science 2025-08-26 Monica Gonzalez-Machorro , Uwe Reichel , Pascal Hecker , Helly Hammer , Hesam Sagha , Florian Eyben , Robert Hoepner , Björn W. Schuller

Single subject prediction of brain disorders from neuroimaging data has gained increasing attention in recent years. Yet, for some heterogeneous disorders such as major depression disorder (MDD) and autism spectrum disorder (ASD), the…

Machine Learning · Computer Science 2022-06-08 Ahmed El Gazzar , Rajat Mani Thomas , Guido Van Wingen

MEG and EEG are noninvasive functional neuroimaging techniques that provide recordings of brain activity with high temporal resolution, and thus provide a unique window to study fast time-scale neural dynamics in humans. However, the…

Applications · Statistics 2015-11-13 Camilo Lamus , Matti S. Hamalainen , Emery N. Brown , Patrick L. Purdon

We currently observe a disconcerting phenomenon in machine learning studies in psychiatry: While we would expect larger samples to yield better results due to the availability of more data, larger machine learning studies consistently show…

Recent literature suggests that the surface electromyography (sEMG) signals have non-stationary statistical characteristics specifically due to random nature of the covariance. Thus suitability of a statistical model for sEMG signals is…

Signal Processing · Electrical Eng. & Systems 2024-10-28 Durgesh Kusuru , Anish C. Turlapaty , Mainak Thakur

The analysis of neural power spectra plays a crucial role in understanding brain function and dysfunction. While recent efforts have led to the development of methods for decomposing spectral data, challenges remain in performing…

Neurons and Cognition · Quantitative Biology 2024-10-29 Johan Medrano , Nicholas A. Alexander , Robert A. Seymour , Peter Zeidman

This study investigates the impact of electrode shift and sensor reapplication on common surface electromyography (sEMG) features in lower limb muscles, factors which have, thus far, precluded clinicians from being able to attribute…

Signal Processing · Electrical Eng. & Systems 2025-09-19 Fraser Douglas , Mona Pei , Calvin Kuo

Despite extensive standardization, diagnostic interviews for mental health disorders encompass substantial subjective judgment. Previous studies have demonstrated that EEG-based neural measures can function as reliable objective correlates…

Machine Learning · Computer Science 2020-11-19 Garrett Honke , Irina Higgins , Nina Thigpen , Vladimir Miskovic , Katie Link , Sunny Duan , Pramod Gupta , Julia Klawohn , Greg Hajcak

Neurophysiological time series recordings like the electroencephalogram (EEG) or local field potentials are obtained from multiple sensors. They can be decoded by machine learning models in order to estimate the ongoing brain state of a…

Signal Processing · Electrical Eng. & Systems 2023-04-14 Pierre Guetschel , Théodore Papadopoulo , Michael Tangermann

Quantifying the complex/multifractal organization of the brain signals is crucial to fully understanding the brain processes and structure. In this contribution, we performed the multifractal analysis of the electroencephalographic (EEG)…

Driving fatigue is a major contributor to traffic accidents and poses a serious threat to road safety. Electroencephalography (EEG) provides a direct measurement of neural activity, yet EEG-based fatigue recognition is hindered by strong…

Other Computer Science · Computer Science 2026-03-06 Yip Tin Po , Jianming Wang , Yutao Miao , Jiayan Zhang , Yunxu Zhao , Xiaomin Ouyang , Zhihong Li , Nevin L. Zhang
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