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While EEG features differentiate Major Depressive Disorder (MDD) from healthy controls (HC), their clinical utility as biomarkers depends on a monotonic trajectory across the disease spectrum, from the acute (AC) phase to the maintenance…

Neurons and Cognition · Quantitative Biology 2026-03-05 Feng Yan , Xuteng Wang , Shuyu Yang , Yue Zhao , Xiaobin Wong , Zhiren Wang

Depression is a public health issue which severely affects one's well being and cause negative social and economic effect for society. To rise awareness of these problems, this publication aims to determine if long lasting effects of…

Machine Learning · Computer Science 2022-02-09 Egils Avots , Klavs Jermakovs , Maie Bachmann , Laura Paeske , Cagri Ozcinar , Gholamreza Anbarjafari

Mental disorders represent critical public health challenges as they are leading contributors to the global burden of disease and intensely influence social and financial welfare of individuals. The present comprehensive review concentrate…

Neurons and Cognition · Quantitative Biology 2021-02-05 Sana Yasin , Syed Asad Hussain , Sinem Aslan , Imran Raza , Muhammad Muzammel , Alice Othmani

Resting-state EEG (rs-EEG) has been demonstrated to aid in Parkinson's disease (PD) diagnosis. In particular, the power spectral density (PSD) of low-frequency bands ({\delta} and {\theta}) and high-frequency bands ({\alpha} and \b{eta})…

Signal Processing · Electrical Eng. & Systems 2023-03-03 Anna Kurbatskaya , Alberto Jaramillo-Jimenez , John Fredy Ochoa-Gomez , Kolbjørn Brønnick , Alvaro Fernandez-Quilez

This study investigates the detection and classification of depressive and non-depressive states using deep learning approaches. Depression is a prevalent mental health disorder that substantially affects quality of life, and early…

Quantitative Methods · Quantitative Biology 2026-01-19 Mohammad Reza Yousefi , Hajar Ismail Al-Tamimi , Amin Dehghani

Multiple Sclerosis (MS) is a chronic disease characterized by progressive or alternate impairment of neurological functions (motor, sensory, visual, and cognitive). Predicting disease progression with a probabilistic and time-dependent…

The incidence of Alzheimer's disease (AD) and other forms of dementia is increasing in most western countries. For a precise and early diagnosis, several examination modalities exist, among them single-photon emission computed tomography…

Major Depressive Disorder (MDD) is a highly prevalent mental health condition, and a deeper understanding of its neurocognitive foundations is essential for identifying how core functions such as emotional and self-referential processing…

According to the World Health Organization, the number of mental disorder patients, especially depression patients, has grown rapidly and become a leading contributor to the global burden of disease. However, the present common practice of…

Machine learning (ML) and deep learning (DL) techniques have been widely applied to analyze electroencephalography (EEG) signals for disease diagnosis and brain-computer interfaces (BCI). The integration of multimodal data has been shown to…

Signal Processing · Electrical Eng. & Systems 2025-01-16 Siqi Zhao , Wangyang Li , Xiru Wang , Stevie Foglia , Hongzhao Tan , Bohan Zhang , Ameer Hamoodi , Aimee Nelson , Zhen Gao

Electroencephalography (EEG) is shown to be a valuable data source for evaluating subjects' mental states. However, the interpretation of multi-modal EEG signals is challenging, as they suffer from poor signal-to-noise-ratio, are highly…

Signal Processing · Electrical Eng. & Systems 2022-04-19 David Bethge , Philipp Hallgarten , Ozan Özdenizci , Ralf Mikut , Albrecht Schmidt , Tobias Grosse-Puppendahl

Depression has been the leading cause of mental-health illness worldwide. Major depressive disorder (MDD), is a common mental health disorder that affects both psychologically as well as physically which could lead to loss of lives. Due to…

Computer Vision and Pattern Recognition · Computer Science 2019-09-05 Anupama Ray , Siddharth Kumar , Rutvik Reddy , Prerana Mukherjee , Ritu Garg

Depression is a major cause of global mental illness and significantly influences suicide rates. Timely and accurate diagnosis is essential for effective intervention. Electroencephalography (EEG) provides a non-invasive and accessible…

Signal Processing · Electrical Eng. & Systems 2025-11-11 Soujanya Hazra , Sanjay Ghosh

Electroencephalography (EEG) provides reliable indications of human cognition and mental states. Accurate emotion recognition from EEG remains challenging due to signal variations among individuals and across measurement sessions. We…

Signal Processing · Electrical Eng. & Systems 2024-12-25 Yun Xiao , Yimeng Zhang , Xiaopeng Peng , Shuzheng Han , Xia Zheng , Dingyi Fang , Xiaojiang Chen

We propose a novel technique to assess functional brain connectivity in EEG/MEG signals. Our method, called Sparsely-Connected Sources Analysis (SCSA), can overcome the problem of volume conduction by modeling neural data innovatively with…

Methodology · Statistics 2010-08-05 Stefan Haufe , Ryota Tomioka , Guido Nolte , Klaus-Robert Mueller , Motoaki Kawanabe

Autism Spectrum Disorder (ASD) is a developmental disorder that often impairs a child's normal development of the brain. According to CDC, it is estimated that 1 in 6 children in the US suffer from development disorders, and 1 in 68…

Signal Processing · Electrical Eng. & Systems 2019-07-03 Yasith Jayawardana , Mark Jaime , Sashi Thapaliya , Sampath Jayarathna

Major depressive disorder is a serious and heterogeneous psychiatric disorder that needs accurate diagnosis. Resting-state functional MRI (rsfMRI), which captures multiple perspectives on brain structure, function, and connectivity, is…

Machine Learning · Computer Science 2023-08-21 Yunsong Luo , Wenyu Chen , Ling Zhan , Jiang Qiu , Tao Jia

Current diagnostic practice in psychiatry is not relying on objective biophysical evidence. Recent pandemic emphasized the need to address the rising number of mood disorders (in particular, depression) cases in a more efficient way. We are…

Neurons and Cognition · Quantitative Biology 2021-10-26 Milena B. Čukić

As an essential element for the diagnosis and rehabilitation of psychiatric disorders, the electroencephalogram (EEG) based emotion recognition has achieved significant progress due to its high precision and reliability. However, one…

Machine Learning · Computer Science 2021-07-19 Hao Chen , Ming Jin , Zhunan Li , Cunhang Fan , Jinpeng Li , Huiguang He