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Purpose: Accurate dose calculation is essential in radiotherapy for precise tumor irradiation while sparing healthy tissue. With the growing adoption of MRI-guided and real-time adaptive radiotherapy, fast and accurate dose calculation on…
Charged particle beams are used in Particle Therapy (PT) to treat oncological patients due to their selective dose deposition in tissues and to their high biological effect in killing cancer cells with respect to photons and electrons used…
Scintillators convert X-ray energy into visible or near-visible photons, enabling applications in high-energy particle detection and X-ray imaging. Increasing scintillator thickness improves X-ray absorption but degrades spatial resolution…
Laser acceleration promises innovation in particle beam therapy of cancer where an ultra-compact accelerator system for cancer beam therapy can become affordable to a broad range of patients. This is not feasible without the introduction of…
Charge-transfer (CT) exciton effects are investigated for the optical absorption spectra of crosslinked C60 systems by using the intermediate exciton theory. We consider the C60-dimers, and the two (and three) molecule systems of the…
Higher intensity of strong-coupling stimulated Brillouin scattering (SC-SBS) amplification is achieved by supplementary Raman amplification. In the new scheme, a Raman pump laser first amplifies the seed pulse in the homogeneous plasma,…
The enhanced terahertz radiation from a new photoconductive antenna (PCA) has been predicted by numerical simulation. Different from the conventional PCA, the proposed PCA has electrodes with sawtooth structures on the edge, which will…
Cs-based semiconductors like $\mathrm{Cs_3Sb}$ and $\mathrm{Cs_2Te}$ are currently used as photocathodes in particle accelerators. Their performance as electron sources critically depends on their interaction with intense laser sources. In…
Very efficient amplification of light-matter waves (polaritons), that are a superposition of cavity photons and excitons [1] has recently been reported[2-11]. The optical gain curve versus the pump power shows a threshold and then saturates…
In this study, cone-beam single projection and axial CT scans are modeled with a software package - DOCTORS, which solves the linear Boltzmann equation using the discrete ordinates method. Phantoms include a uniform 35 cm diameter water…
Purpose: To investigate the validity of two Monte Carlo simulation absolute dosimetry approaches in the case of a small field dedicated `D'-shaped collimator used for the retinoblastoma treatment with external photon beam radiotherapy.…
Proton beam therapy has been developed to irradiate the tumor with higher precision and dose conformity compared to conventional X-ray irradiation. The dose conformity of this treatment modality may be further improved if narrower proton…
The design of the Linac Coherent Light Source assumes that a low-emittance, 1-nC, 10-ps beam will be available for injection into the 15-GeV linac. The proposed rf photocathode injector that will provide a 150-MeV beam with rms normalized…
Using spectral hole-burning-based ultraslow group velocity in a dilute solid medium, we report enhanced photon echo efficiency three orders of magnitude higher than that in a nonslow light regime. The enhancement is due to exponentially…
Understanding how the electronic excitation of DNA changes in response to different high-energy particles is central to advancing ion beam cancer therapy. While protons have been the predominant ion of choice in beam cancer therapy, heavier…
Liquid scintillating phantoms have been proposed as a means to perform real-time 3D dosimetry for proton therapy treatment plan verification. We have studied what effect radiation damage to the scintillator will have upon this application.…
We report a significant enhancement of room-temperature photoluminescence from trivalent erbium-doped (Er3+) silicon nitride (Si3N4) metasurfaces at the telecommunication wavelength prepared via ion implantation. The metasurfaces,…
Background: Promising results for mammary carcinoma treatment with photodynamic therapy (PDT) presuppose a careful selection of irradiation light wavelength. Methods: 4T1 tumors implanted in NOD-SCID mice were treated with Metvix-PDT under…
A long laser beam propagating through an underdense plasma produces a positively charged ion channel by expelling plasma electrons in the transverse direction. We consider the dynamics of a test electron in a resulting two-dimensional…
As photon counting detectors are being explored for medical and industrial imaging applications, there is a critical need to understand spectral characteristics of scattered x-ray photons. Scattered radiation is detrimental to x-ray imaging…