Related papers: Simulation dose enhancement in radiotherapy caused…
Background: With the advent of Intensity Modulated Radiotherapy (IMRT) and recently, Volumetric Modulated Arc Therapy (VMAT), treatment planning using Flattening Filter Free (FFF) beams can meet all of the energy requirements in radiation…
Computed Tomography (CT) measures the attenuation coefficient of an object and converts the value assigned to each voxel into a CT number. In radiation therapy, CT number, which is directly proportional to the linear attenuation…
As depth increases, linear energy transfer (LET) rises toward the distal edge of the Bragg peak, boosting the radiobiological effectiveness (RBE). To manage the biological variation and limit normal-tissue damage, LET-modifying objective…
The physical and clinical benefits of charged particle therapy (CPT) are well recognised and recent developments have led to the rapid emergence of facilities, resulting in wider adoption worldwide. Nonetheless, the availability of CPT and…
Ultra-high dose rate electron sources require dose rate independent dosimeters and a calibrated dose control system for accurate delivery. In this study, we developed a single-pulse dose monitoring and a real-time dose-based control system…
Background: Recently, the popularity of dual-layer flat-panel detector (DL-FPD) based dual-energy cone-beam CT (DE-CBCT) imaging has been increasing. However, the image quality of DE-CBCT remains constrained by the Compton scattered X-ray…
We investigate by particle-in-cell simulations in two and three dimensions the laser-plasma interaction and the proton acceleration in multilayer targets where a low density "near-critical" layer of a few micron thickness is added on the…
In this paper we study photon emission in the interaction of the laser beam with an under-dense target and the attached reflecting plasma mirror. Photons are emitted due to the inverse Compton scattering when accelerated electrons interact…
Irradiations at Ultra High Dose Rate (UHDR) regimes, exceeding 40 Gy/s in single fractions lasting less than 200 ms, have shown an equivalent antitumor effect compared to conventional radio-therapy with reduced harm to normal tissues. This…
Purpose: To improve target coverage and reduce the dose in the surrounding organs-at-risks (OARs), we developed an image-guided treatment method based on a precomputed library of treatment plans controlled and delivered in real-time.…
Though wakefield acceleration in crystal channels has been previously proposed, x-ray wakefield acceleration has only recently become a realistic possibility since the invention of the single-cycled optical laser compression technique. We…
Electron capture processes are important in the search for new physics. In this context, a high capture rate is desired. We investigate the possibility of enhancing the electron capture rate by irradiating laser beam to ''atom''. The…
Bound quasiparticles, negatively charged trions and neutral excitons, are associated with the direct optical transitions at the K-points of the Brillouin zone for monolayer MoS$_2$. The change in the carrier concentration, surrounding…
Bremsstrahlung photon beams produced by medical linear accelerators are currently the most commonly used method of radiation therapy for cancerous tumors. Photons with energies greater than 8-10 MeV potentially generate neutrons through…
A new self-injection scheme is proposed for the laser wakefield accelerator in the nonlinear (cavity) regime using a pair of matched, copropagating laser pulses which yields a pC electron bunch. By tuning their relative delay and intensity,…
The Circular Electron-Positron Collider (CEPC) can also work as a powerful and excellent synchrotron light source, which can generate high-quality synchrotron radiation. This synchrotron radiation has potential advantages in the medical…
$Objective$. Obtaining the intrinsic dose distributions in particle therapy is a challenging problem that needs to be addressed by imaging algorithms to take advantage of secondary particle detectors. In this work, we investigate the…
We present numerical simulations results on the injection and acceleration of a 10 MeV, 10 pC electrons beam in a plasma wave generated in a gas cell by a 2J, 45 fs laser beam. This modeling is related to the ESCULAP project in which the…
The generation of the ultra-bright beams required by modern accelerators and drivers of free-electron lasers (FELs) has generally relied on chicane-based bunch compressions that often result in the microbunching instability. Following…
Radiation therapy is one of the most common cancer treatments, and dose optimization and targeting of radiation are crucial since both cancerous and healthy cells are affected. Different mathematical and computational approaches have been…