Related papers: Cell selective manipulation with single beam acous…
The manipulation of acoustic waves plays an important role in a wide range of applications. Currently, acoustic wave manipulation typically relies on either acoustic metasurfaces or phased array transducers. The elements of metasurfaces are…
The constant interplay and information exchange between cells and their micro-environment are essential to their survival and ability to execute biological functions. To date, a few leading technologies such as traction force microscopy,…
Optical tweezers has emerged as a powerful tool in manipulating microscopic particles and in measuring weak forces of the order of a pico-Newton. As a result, it has found wide applications ranging from material science to biology.…
Holographic optical tweezers use computer-generated holograms to create arbitrary three-dimensional configurations of single-beam optical traps useful for capturing, moving and transforming mesoscopic objects. Through a combination of…
Anchorage-dependent cells collect information on the mechanical properties of the environment through their contractile machineries and use this information to position and orient themselves. Since the probing process is anisotropic,…
We present a detailed theoretical study of the recent proposal for selective nanomanipulation of nanometric particles above a substrate using near-field optical forces [Chaumet {\it et al.} Phys. Rev. Lett. {\bf 88}, 123601 (2002)].…
We have recently demonstrated the creation of regular strings of neutral caesium atoms in a standing wave optical dipole trap using optical tweezers [Y. Miroshnychenko et al., Nature, in press (2006)]. The rearrangement is realized…
The ability to manipulate or separate a biological small particle, such as a living cell and embryo, is fundamental needed to many biological and medical applications. The insulator-based dielectrophoresis (iDEP) trapping is composed of…
We report the simultaneous characterization of time- and force-dependent mechanical properties of adherent cells in the physiologically relevant regime of large forces. We used magnetic tweezers to apply forces to magnetic beads bound to…
Biophysical force spectroscopy tools - for example optical tweezers, magnetic tweezers, atomic force microscopy, - have been used to study elastic, mechanical, conformational and dynamic properties of single biological specimens from single…
Herein, charged microbeads handled with optical tweezers are used as a sensitive probe for simultaneous measurements of electrophoretic and dielectrophoretic forces. We first determine the electric charge carried by a single bead by keeping…
Optical tweezers employing forces produced by light underpin important manipulation tools in many areas of applied and biological physics. Conventional optical tweezers are based on refractive optics, and they require excessive auxiliary…
Optical tweezers (OT) have become an essential technique in several fields of physics, chemistry, and biology as precise micromanipulation tools and microscopic force transducers. Quantitative measurements require the accurate calibration…
Optoelectronic tweezer-driven microrobots (OETdMs) are a versatile micromanipulation technology based on the use of light induced dielectrophoresis to move small dielectric structures (microrobots) across a photoconductive substrate. The…
Standard optical tweezers rely on optical forces that arise when a focused laser beam interacts with a microscopic particle: scattering forces, which push the particle along the beam direction, and gradient forces, which attract it towards…
Many essential cellular functions depend on the viscoelastic properties of the cytoplasm. While techniques such as optical tweezers and atomic force microscopy can measure these properties, their reliance on localized probes prevents…
Acoustic tweezers enable non-contact manipulation of microscale objects, but quantitative in situ evaluation of the peak local pressure amplitude remains difficult in confined devices. Conventional hydrophone-based measurements are often…
Accurately measuring cell stiffness is challenging due to the invasiveness of traditional methods like atomic force microscopy (AFM) and optical stretching. We introduce a non-invasive off-axis system using holographic imaging and acoustic…
Realizing optical manipulation of microscopic objects is crucial in the research fields of life science, condensed matter physics and physical chemistry. In non-liquid environments, this task is commonly regarded as difficult due to strong…
Rotational optical tweezers are used to probe the mechanical properties of unknown microsystems. Quantifying the angular trap stiffness is essential for interpreting the rotational dynamics of probe particles. While methods to determine…