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Minimally invasive interventions performed inside brain vessels with the synergistic use of microcatheters pushed over guidewires have revolutionized the way aneurysms, stroke, arteriovenous malformations, brain tumors and other…

Pulsed-laser dry printing of noble-metal microrings with a tunable internal porous structure, which can be revealed via an ion-beam etching post-procedure, was demonstrated. Abundance and average size of the pores inside the microrings were…

Applied Physics · Physics 2017-09-27 S. Syubaev , A. Nepomnyashchiy , E. Mitsai , E. Pustovalov , O. Vitrik , S. Kudryashov , A. Kuchmizhak

We present a simple lithographic method for fabrication of microresonator devices at the optical fiber surface. First, we undress the predetermined surface areas of a fiber segment from the polymer coating with a focused CO2 laser beam.…

Optics · Physics 2021-04-21 N. Toropov , S. Zaki , T. Vartanyan , M. Sumetsky

Assembly of colloidal particles on fluid interfaces is a promising technique for synthesizing two-dimensional micro-crystalline materials useful in fields as diverse as biomedicine1, materials science2, mineral flotation3 and food…

Soft Condensed Matter · Physics 2007-05-23 Anand Bala Subramaniam , Manouk Abkarian , Howard A. Stone

Biological systems have been theoretically predicted to support phononic topological wave-modes, similar to the ones existing in meta-materials. The existing methods to measure these modes, however cannot be applied to biological systems;…

Biological Physics · Physics 2023-03-03 Ssu-Ying Chen , Arooj Aslam , David J. Apigo , Sagnik Basuray , Camelia Prodan

This work reports on the fabrication of microbump structures on Ni films by single-pulse, localized laser irradiation. Conditions for the reproducible formation of such microstructures have been identified in terms of laser-irradiation and…

Systems and Control · Electrical Eng. & Systems 2023-11-20 Srikanth Itapu , Vamsi Borra , Daniel G. Georgiev

A procedure and optical concept is introduced for ultrashort pulsed laser cleaving of transparent materials with tailored edges in a single pass. The procedure is based on holographically splitting a number of foci along the desired edge…

We report on the fabrication of micro-axicons made of glass by laser-assisted wet etching (LAE) and laser polishing. The employed technique, relying on an efficient direct-writing process by femtosecond laser, allows revealing high fidelity…

The fabrication of multilayered heterostructures is essential for advancing microelectronic and biosensing technologies. Conventional top-down manufacturing techniques are often cost-prohibitive and unsuitable for biomedical applications.…

Chemical Physics · Physics 2025-06-13 Anand Dev Ranjan , Suyash Narayan Amzare , Subhrokoli Ghosh , Ayan Banerjee

We present a new method for modeling tissue perfusion on the capillary scale. The microvasculature is represented by a network of one-dimensional vessel segments embedded in the extra-vascular space. Vascular and extra-vascular space…

Computational Physics · Physics 2020-03-23 Timo Koch , Martin Schneider , Rainer Helmig , Patrick Jenny

On-chip optical trapping systems allow for high scalability and lower the barrier to access. Systems capable of trapping multiple particles typically come with high cost and complexity. Here we present a technique for making parabolic…

Analysis of three-dimensional biological samples is critical to understanding tissue function and the mechanisms of disease. Many chronic conditions, like neurodegenerative diseases and cancers, correlate with complex tissue changes that…

Biological Physics · Physics 2019-11-06 Jiaming Guo , Camille Artur , Jason L. Eriksen , David Mayerich

Laser micro-welding is an advanced manufacturing method today applied in various domains. However, important physical limitations have prevented so far to demonstrate its applicability in silicon and other technology-essential…

Applied Physics · Physics 2022-03-31 Pol Sopeña , Andong Wang , Alexandros Mouskeftaras , David Grojo

The inkjet-fabricated liquid crystal (LC) droplet device not only capitalizes on the intrinsic birefringence properties of liquid crystals but also leverages the hemispherical shape of droplet devices on substrates. This configuration…

The microfluidic probe (MFP) is a non-contact, scanning microfluidic technology for local (bio)chemical processing of surfaces based on hydrodynamically confining nanoliter volumes of liquids over tens of micrometers. We present here a…

Tissues and Organs · Quantitative Biology 2014-08-19 J. F. Cors , R. D. Lovchik , E. Delamarche , G. V. Kaigala

High-energy, few-cycle laser pulses are essential for numerous applications in the fields of ultrafast optics and strong-field physics, due to their ultrafast temporal resolution and high peak intensity. In this work, different from the…

3D printing technologies are currently enabling the fabrication of objects with complex architectures and tailored properties. In such framework, the production of 3D optical structures, which are typically based on optical transparent…

Applied Physics · Physics 2018-07-11 L. Persano , F. Cardarelli , A. Arinstein , S. Uttiya , E. Zussman , D. Pisignano , A. Camposeo

Minimally invasive medical procedures, such as endovascular catheterization, have drastically reduced procedure time and associated complications. However, many regions inside the body, such as in the brain vasculature, still remain…

Applied Physics · Physics 2021-01-27 Lucio Pancaldi , Pietro Dirix , Adele Fanelli , Diego Ghezzi , Mahmut Selman Sakar

Lab-on-a-chip (LOC) forms the basis of the new-generation portable analytical systems. LOC allows the manipulation of ultralow flows of liquid reagents and multistep reactions on a microfluidic chip, which requires a robust and precise…

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