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Lensless imaging enables exceptionally compact fluorescence sensors, advancing applications in \textit{in vivo} imaging and low-cost, point-of-care diagnostics. These sensors require a filter to block the excitation light while passing…

Image and Video Processing · Electrical Eng. & Systems 2026-02-20 Lukas Harris , Micah Roschelle , Jack Bartley , Mekhail Anwar

Astronomical adaptive optics (AO) is a critical approach to enable ground-based diffraction-limited imaging and high contrast science, with the potential to enable habitable exoplanet imaging on future extremely large telescopes. However,…

Instrumentation and Methods for Astrophysics · Physics 2024-06-18 Benjamin L. Gerard , Aaron Lemmer , Bautista R. Fernandez , Xiaoxing Xia , Cesar Laguna , Mike Kim , Stephen Mark Ammons , Brian Bauman , Lisa Poyneer

Since its beginnings, diffraction-limited ground-based adaptive optics (AO) imaging has been limited to wavelengths in the near IR ({\lambda} > 1 micron) and longer. Visible AO ({\lambda} < 1 micron) has proven to be difficult because…

Instrumentation and Methods for Astrophysics · Physics 2010-08-03 Derek Kopon , Jared R. Males , Laird M. Close , Victor Gasho

Microscopy and optical imaging are drastically limited by the inhomogeneities encountered by the light while propagating from the object of interest to the detection system. In this context, adaptive optics and wavefront manipulation are…

Optics · Physics 2017-01-23 Diego Di Battista

Advanced wavefront sensors (WFS) are essential for enabling new science cases for telescopes that utilize adaptive optics (AO) systems. While complex field WFS -- those that estimate the electric field phase and amplitude through…

Instrumentation and Methods for Astrophysics · Physics 2025-08-21 D. Angelica Huerta , Justin R. Crepp , Caleb G. Abbott , Brian Joseph

Adaptive optics (AO) is a technique to improve the resolution of ground-based telescopes by correcting, in real-time, optical aberrations due to atmospheric turbulence and the telescope itself. With the rise of Giant Segmented Mirror…

Multiconjugate adaptive optics (MCAO) systems have the potential to deliver diffraction-limited images over much larger fields of view than traditional single conjugate adaptive optics systems. In MCAO, the high altitude deformable mirrors…

Solar and Stellar Astrophysics · Physics 2022-01-19 Marcos A. van Dam , Yolanda Martín Hernando , Miguel Núñez Cagigal , Luzma M. Montoya

As new large-scale astronomical surveys greatly increase the number of objects targeted and discoveries made, the requirement for efficient follow-up observations is crucial. Adaptive optics imaging, which compensates for the image-blurring…

Rather than using an adaptive optics (AO) system to correct a telescope s entire pupil, it can instead be used to more finely correct a smaller sub-aperture. Indeed, existing AO systems can be used to correct a sub-aperture 1/3 to 1/2 the…

Astrophysics · Physics 2009-11-13 E. Serabyn , K. Wallace , M. Troy , B. Mennesson , P. Haguenauer , R. Gappinger , R. Burruss

Many optical systems use acousto-optics for fast steering of light. However, acousto-optic (AO) light diffraction permits manipulation and shaping of light fields in a much broader sense including holography. While acousto-optic devices…

Optics · Physics 2022-03-15 Walther Akemann , Laurent Bourdieu

Control of light through a microscope objective with a high numerical aperture is a common requirement in applications such as optogenetics, adaptive optics, or laser processing. Light propagation, including polarization effects, can be…

Optics · Physics 2023-03-22 Ivan Vishniakou , Johannes D. Seelig

The Multiconjugate adaptive Optic Relay For ELT Observations (MORFEO, formerly known as MAORY) is the adaptive optics (AO) module for the Extremely Large Telescope (ELT) aimed at providing a 1 arcmin corrected field to the Multi-AO Imaging…

Instrumentation and Methods for Astrophysics · Physics 2022-09-01 Guido Agapito , Lorenzo Busoni , Giulia Carlà , Cédric Plantet , Simone Esposito , Paolo Ciliegi

Over the past fifty years, wavefront sensing technology has continuously evolved from basic techniques to high-precision systems, serving as a core methodology in adaptive optics (AO). Beyond traditional wavefront retrieval methods based on…

Optics · Physics 2025-05-13 Rundong Fan , Zichao Wang , Pei Li , Lei Huang

Fluorescence Correlation Spectroscopy (FCS) yields measurement parameters (number of molecules, diffusion time) that characterize the concentration and kinetics of fluorescent molecules within a supposedly known observation volume. Absolute…

Biological Physics · Physics 2011-12-23 Charles Edouard Leroux , Irène Wang , Jacques Derouard , Antoine Delon

Several telescopes include large Deformable Mirrors (DM) located directly inside the telescope. These adaptive telescopes trigger new constraints for the calibration of the Adaptive Optics (AO) systems as they usually offer no access to an…

Instrumentation and Methods for Astrophysics · Physics 2019-01-10 C. T. Heritier , S. Esposito , T. Fusco , B. Neichel , S. Oberti , R. Briguglio , G. Agapito , A. Puglisi , E. Pinna , P. -Y. Madec

The SINFONI instrument for ESO's VLT combines integral field spectroscopy and adaptive optics (AO). We discuss detailed simulations of the adaptive optics module. These simulations are aimed at assessing the AO module performance,…

Astrophysics · Physics 2009-11-10 Anthony G A Brown , Enrico Fedrigo , Paul van der Werf

Confocal Raman microscopy, a highly specific and label-free technique for the microscale study of thick samples, often presents difficulties due to weak Raman signals. Inhomogeneous samples introduce wavefront aberrations that further…

Multi-object adaptive optics (MOAO) has been demonstrated by the CANARY instrument on the William Herschel Telescope. However, for proposed MOAO systems on the next generation Extremely Large Telescopes, such as EAGLE, many challenges…

Instrumentation and Methods for Astrophysics · Physics 2015-06-16 A. G. Basden , N. A. Bharmal , R. M. Myers , S. L. Morris , T. J. Morris

There are scientific and technological needs to improve the co-phasing of the primary mirrors of segmented telescopes. We have developed a methodology for using the wavefront sensor of an adaptive optics (AO) system to disentangle the phase…

Instrumentation and Methods for Astrophysics · Physics 2025-03-05 Benjamin Calvin , Michael Fitzgerald , Sam Ragland

Two-wavelength adaptive optics (AO) systems sense turbulence-induced wavefront distortions using an artificial beacon or natural guidestar at one wavelength, while correcting and possibly transmitting at another. Although most existing AO…

Optics · Physics 2025-05-02 Milo W. Hyde , Matthew Kalensky , Mark F. Spencer