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Multimodal deep learning has shown strong potential in medical applications by integrating heterogeneous data sources such as medical images and structured clinical variables. However, most existing approaches implicitly assume complete…

Machine Learning · Computer Science 2026-05-13 Camillo Maria Caruso , Valerio Guarrasi , Paolo Soda

Purpose High dimensional, multimodal data can nowadays be analyzed by huge deep neural networks with little effort. Several fusion methods for bringing together different modalities have been developed. Given the prevalence of…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Christian Gapp , Elias Tappeiner , Martin Welk , Karl Fritscher , Elke Ruth Gizewski , Rainer Schubert

Effectively leveraging multimodal data such as various images, laboratory tests and clinical information is gaining traction in a variety of AI-based medical diagnosis and prognosis tasks. Most existing multi-modal techniques only focus on…

Image and Video Processing · Electrical Eng. & Systems 2023-11-28 Yingying Fang , Shuang Wu , Sheng Zhang , Chaoyan Huang , Tieyong Zeng , Xiaodan Xing , Simon Walsh , Guang Yang

Finding the underlying relationships among multiple imaging modalities in a coherent fashion is one of challenging problems in the multimodal analysis. In this study, we propose a novel multimodal network approach based on multidi-…

Quantitative Methods · Quantitative Biology 2016-02-26 Hyekyoung Lee , Hyejin Kang , Moo K. Chung , Seonhee Lim , Bung-Nyun Kim , Dong Soo Lee

Localizing neuronal activity in the brain, both in time and in space, is a central challenge to advance the understanding of brain function. Because of the inability of any single neuroimaging techniques to cover all aspects at once, there…

Neurons and Cognition · Quantitative Biology 2013-07-09 Yaroslav O. Halchenko , Michael Hanke , James V. Haxby , Stephen Jose Hanson , Christoph S. Herrmann

Multimodal learning seeks to utilize data from multiple sources to improve the overall performance of downstream tasks. It is desirable for redundancies in the data to make multimodal systems robust to missing or corrupted observations in…

Computer Vision and Pattern Recognition · Computer Science 2024-10-14 Md Kaykobad Reza , Ashley Prater-Bennette , M. Salman Asif

Medical records often consist of different modalities, such as images, text, and tabular information. Integrating all modalities offers a holistic view of a patient's condition, while analyzing them longitudinally provides a better…

Computer Vision and Pattern Recognition · Computer Science 2024-03-25 Boqi Chen , Junier Oliva , Marc Niethammer

Multimodal MRI provides critical complementary information for accurate brain tumor segmentation. However, conventional methods struggle when certain modalities are missing due to issues such as image quality, protocol inconsistencies,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-03 Runze Cheng , Xihang Qiu , Ming Li , Ye Zhang , Chun Li , Fei Yu

This paper introduces an innovative multi-modal fusion deep learning approach to overcome the drawbacks of traditional single-modal recognition techniques. These drawbacks include incomplete information and limited diagnostic accuracy.…

Computer Vision and Pattern Recognition · Computer Science 2024-06-28 Xiaoyi Liu , Hongjie Qiu , Muqing Li , Zhou Yu , Yutian Yang , Yafeng Yan

Multi-modal data comprising imaging (MRI, fMRI, PET, etc.) and non-imaging (clinical test, demographics, etc.) data can be collected together and used for disease prediction. Such diverse data gives complementary information about the…

Machine Learning · Computer Science 2018-12-27 Anees Kazi , S. Arvind krishna , Shayan Shekarforoush , Karsten Kortuem , Shadi Albarqouni , Nassir Navab

The cross-modal synthesis between structural magnetic resonance imaging (sMRI) and functional network connectivity (FNC) is a relatively unexplored area in medical imaging, especially with respect to schizophrenia. This study employs…

Image and Video Processing · Electrical Eng. & Systems 2023-09-18 Yuda Bi , Anees Abrol , Jing Sui , Vince Calhoun

Multimodal deep learning, especially vision-language models, have gained significant traction in recent years, greatly improving performance on many downstream tasks, including content moderation and violence detection. However, standard…

Computer Vision and Pattern Recognition · Computer Science 2024-08-05 Zhuokai Zhao , Harish Palani , Tianyi Liu , Lena Evans , Ruth Toner

It is necessary for clinicians to comprehensively analyze patient information from different sources. Medical image fusion is a promising approach to providing overall information from medical images of different modalities. However,…

Image and Video Processing · Electrical Eng. & Systems 2019-12-12 Fanda Fan , Yunyou Huang , Lei Wang , Xingwang Xiong , Zihan Jiang , Zhifei Zhang , Jianfeng Zhan

Network models are powerful tools for gaining new insights from complex biological data. Most lines of investigation in biology involve comparing datasets in the setting where the same predictors are measured across multiple studies or…

An active challenge in developing multimodal machine learning (ML) models for healthcare is handling missing modalities during training and deployment. As clinical datasets are inherently temporal and sparse in terms of modality presence,…

Machine Learning · Computer Science 2026-05-08 Andrew Wang , Ellie Pavlick , Ritambhara Singh

The combination of electronic health records (EHR) and medical images is crucial for clinicians in making diagnoses and forecasting prognosis. Strategically fusing these two data modalities has great potential to improve the accuracy of…

Image and Video Processing · Electrical Eng. & Systems 2024-10-24 Wenfang Yao , Kejing Yin , William K. Cheung , Jia Liu , Jing Qin

\textbf{Objective:} Alzheimer's disease (AD) is the most prevalent form of dementia worldwide, encompassing a prodromal stage known as Mild Cognitive Impairment (MCI), where patients may either progress to AD or remain stable. The objective…

Cross-modal fusion of different types of neuroimaging data has shown great promise for predicting the progression of Alzheimer's Disease(AD). However, most existing methods applied in neuroimaging can not efficiently fuse the functional and…

Image and Video Processing · Electrical Eng. & Systems 2022-07-15 Junren Pan , Shuqiang Wang

This proof-of-concept study introduces a novel multimodal framework combining synchronized EEG-fNIRS modalities with neuronal avalanche analysis to identify early network dysfunction in Alzheimer's disease. The approach leverages…

Neurons and Cognition · Quantitative Biology 2026-03-25 Eva Guttmann-Flury , Yun-Hsuan Chen , Qiaoyuan Xiang , Hao Zhang , Mohamad Sawan

Fault diagnosis in multimode processes plays a critical role in ensuring the safe operation of industrial systems across multiple modes. It faces a great challenge yet to be addressed - that is, the significant distributional differences…

Machine Learning · Computer Science 2025-07-24 Guangqiang Li , M. Amine Atoui , Xiangshun Li