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Multimodal pathological images are usually in clinical diagnosis, but computer vision-based multimodal image-assisted diagnosis faces challenges with modality fusion, especially in the absence of expert-annotated data. To achieve the…
Multimodal AI has demonstrated superior performance over unimodal approaches by leveraging diverse data sources for more comprehensive analysis. However, applying this effectiveness in healthcare is challenging due to the limited…
Multimodal medical image fusion (MMIF) extracts the most meaningful information from multiple source images, enabling a more comprehensive and accurate diagnosis. Achieving high-quality fusion results requires a careful balance of…
This paper presents a general framework for obtaining interpretable multivariate discriminative models that allow efficient statistical inference for neuroimage analysis. The framework, termed generative discriminative machine (GDM),…
Depression is a leading cause of death worldwide, and the diagnosis of depression is nontrivial. Multimodal learning is a popular solution for automatic diagnosis of depression, and the existing works suffer two main drawbacks: 1) the…
Multimodal neuroimaging modeling has becomes a widely used approach but confronts considerable challenges due to heterogeneity, which encompasses variability in data types, scales, and formats across modalities. This variability…
Synthesizing missing modalities in multi-modal magnetic resonance imaging (MRI) is vital for ensuring diagnostic completeness, particularly when full acquisitions are infeasible due to time constraints, motion artifacts, and patient…
Early detection of Alzheimer's disease's precursor stages is imperative for significantly enhancing patient outcomes and quality of life. This challenge is tackled through a semi-supervised multi-modal diagnosis framework. In particular, we…
Multimodal medical information processing is currently the epicenter of intense interdisciplinary research, as proper data fusion may lead to more accurate diagnoses. Moreover, multimodality may disambiguate cases of co-morbidity. This…
Accurate diagnosis of Alzheimer's disease (AD) is essential for enabling timely intervention and slowing disease progression. Multimodal diagnostic approaches offer considerable promise by integrating complementary information across…
Multimodal neuroimaging provides complementary insights for Alzheimer's disease diagnosis, yet clinical datasets frequently suffer from missing modalities. We propose ACADiff, a framework that synthesizes missing brain imaging modalities…
Normative modelling is an emerging method for understanding the underlying heterogeneity within brain disorders like Alzheimer Disease (AD) by quantifying how each patient deviates from the expected normative pattern that has been learned…
Depression is a highly prevalent and disabling condition that incurs substantial personal and societal costs. Current depression diagnosis involves determining the depression severity of a person through self-reported questionnaires or…
Alzheimer's Disease (AD) is a complex neurodegenerative disorder marked by memory loss, executive dysfunction, and personality changes. Early diagnosis is challenging due to subtle symptoms and varied presentations, often leading to…
Diagnosing dementia, particularly for Alzheimer's Disease (AD) and frontotemporal dementia (FTD), is complex due to overlapping symptoms. While magnetic resonance imaging (MRI) and positron emission tomography (PET) data are critical for…
Depression poses serious public health risks, including suicide, underscoring the urgency of timely and scalable screening. Multimodal automatic depression detection (ADD) offers a promising solution; however, widely studied audio- and…
Multimodal magnetic resonance imaging (MRI) is crucial for brain tumor segmentation, with many methods leveraging its four key modalities to capture complementary information for effective sub-region analysis. However, the absence of…
Understanding the biological and behavioral heterogeneity underlying psychiatric disorders is critical for advancing precision diagnosis, treatment, and prevention. This paper addresses the scientific question of how multimodal data,…
Clinical decision-making relies on the integrated analysis of medical images and the associated clinical reports. While Vision-Language Models (VLMs) can offer a unified framework for such tasks, they can exhibit strong biases toward one…
Learning multimodal representations from medical images and other data sources can provide richer information for decision-making. While various multimodal models have been developed for this, they overlook learning features that are both…