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In this paper we derive a pore-scale model for permeable biofilm formation in a two-dimensional pore. The pore is divided in two phases: water and biofilm. The biofilm is assumed to consist of four components: water, extracellular polymeric…

The focus of this paper is the numerical solution of a pore-scale model for the growth of a permeable biofilm. The model includes water flux inside the biofilm, different biofilm components, and shear stress on the biofilm-water interface.…

Fluid Dynamics · Physics 2020-07-14 David Landa-Marbán , Iuliu S. Pop , Kundan Kumar , Florin A. Radu

A bacterial biofilm is an aggregate of micro-organisms growing fixed onto a solid surface, rather than floating freely in a liquid. Biofilms play a major role in various practical situations such as surgical infections and water treatment.…

Analysis of PDEs · Mathematics 2023-06-06 Tommi Brander , Daniel Lesnic , Kai Cao

An implicit Euler finite-volume scheme for a parabolic reaction-diffusion system modeling biofilm growth is analyzed and implemented. The system consists of a degenerate-singular diffusion equation for the biomass fraction, which is coupled…

Numerical Analysis · Mathematics 2021-10-29 Christoph Helmer , Ansgar Jüngel , Antoine Zurek

In this paper, we study a parabolic reaction diffusion system with constraints that model biofilm growth. Within a unified framework encompassing multiple numerical schemes, we derive the first general convergence rates for approximating…

Numerical Analysis · Mathematics 2025-11-05 Yahya Alnashri

We perform mathematical anaysis of the biofilm development process. A model describing biomass growth is proposed: It arises from coupling three parabolic nonlinear equations: a biomass equation with degenerate and singular diffusion, a…

Analysis of PDEs · Mathematics 2017-03-14 Maria Gokieli , Nobuyuki Kenmochi , Marek Niezgódka

Biofilm growth changes many physical properties of porous media such as porosity, permeability and mass transport parameters. The growth depends on various environmental conditions, and in particular, on flow rates. Modeling the evolution…

A dissipative particle dynamics (DPD) model for the quantitative simulation of biofilm growth controlled by substrate (nutrient) consumption, advective and diffusive substrate transport, and hydrodynamic interactions with fluid flow…

Computational Physics · Physics 2018-08-03 Zhijie Xu , Paul Meakin , Alexandre Tartakovsky , Timothy. D. Scheibe

A mathematical model for emerging contaminants sorption in multispecies biofilms, based on a continuum approach and mass conservation principles is presented. Diffusion of contaminants within the biofilm is described using a…

Cell Behavior · Quantitative Biology 2017-06-15 Luigi Frunzo

A free boundary value problem related to the genesis of multispecies granular biofilms is presented. The granular biofilm is modelled as a spherical free boundary domain with radial symmetry. The proposed model is conceived in the framework…

Analysis of PDEs · Mathematics 2023-01-31 F. Russo , M. R. Mattei , A. Tenore , B. D'Acunto , V. Luongo , L. Frunzo

A micro-hydromechanical model for granular materials is presented. It combines the discrete element method (DEM) for the modeling of the solid phase and a pore-scale finite volume (PFV) formulation for the flow of an incompressible pore…

Soft Condensed Matter · Physics 2013-12-17 Emanuele Catalano , Bruno Chareyre , Eric Barthélémy

We propose and analyse numerical schemes for a system of quasilinear, degenerate evolution equations modelling biofilm growth as well as other processes such as flow through porous media and the spreading of wildfires. The first equation in…

Numerical Analysis · Mathematics 2024-04-05 R. K. H. Smeets , K. Mitra , I. S. Pop , S. Sonner

We analyze the mathematical properties of a multi-species biofilm cross-diffusion model together with very general reaction terms and mixed Dirichlet-Neumann boundary conditions on a bounded domain. This model belongs to the class of…

Analysis of PDEs · Mathematics 2018-05-08 Esther S. Daus , Josipa-Pina Milišić , Nicola Zamponi

In this paper, we derive upscaled equations for modelling biofilm growth in porous media. The resulting macro-scale mathematical models consider permeable multi-species biofilm including water flow, transport, detachment and reactions. The…

In this paper, we consider the inverse problem of determining some coefficients within a coupled nonlinear parabolic system, through boundary observation of its non-negative solutions. In the physical setup, the non-negative solutions…

Analysis of PDEs · Mathematics 2024-04-23 Hongyu Liu , Catharine W. K. Lo

We consider a quasilinear degenerate diffusion-reaction system that describes biofilm formation. The model exhibits two non-linear effects: a power law degeneracy as one of the dependent variables vanishes and a super diffusion singularity…

Numerical Analysis · Mathematics 2017-08-22 M. Ghasemi , H. J. Eberl

We present a contribution to the field of system identification of partial differential equations (PDEs), with emphasis on discerning between competing mathematical models of pattern-forming physics. The motivation comes from developmental…

Computational Physics · Physics 2024-03-28 Zhenlin Wang , Xun Huan , Krishna Garikipati

A multiscale mathematical model describing the genesis and ecology of algal-bacterial photogranules and the metals biosorption on their solid matrix within a sequencing batch reactor (SBR) is presented. The granular biofilm is modelled as a…

Cell Behavior · Quantitative Biology 2023-01-31 F. Russo , A. Tenore , M. R. Mattei , L. Frunzo

A multiscale mathematical model is presented to describe the de novo granulation and the evolution of multispecies granular biofilms within a continuous reactor. The granule is modelled as a spherical free boundary domain with radial…

Populations and Evolution · Quantitative Biology 2022-02-02 A. Tenore , F. Russo , M. R. Mattei , B. D'Acunto , G. Collins , L. Frunzo

In this paper, we consider a model with tumor microenvironment involving nutrient density, extracellular matrix and matrix-degrading enzymes, which satisfy a coupled system of PDEs with a free boundary. For this coupled parabolic-hyperbolic…

Analysis of PDEs · Mathematics 2018-08-24 Rui Li , Bei Hu
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