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Related papers: SIR dynamics with Vaccination in a large Configura…

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Background: Network-based interventions are most powerful against epidemics when the full network structure is known. However, resource constraints often require decisions based on partial network data. We investigated how the effectiveness…

Populations and Evolution · Quantitative Biology 2018-03-30 Yingrui Yang , Ashley McKhann , Guy Harling , Jukka-Pekka Onnela

This paper analyses the optimal control of infectious disease propagation using a classic susceptible-infected-recovered (SIR) model characterised by permanent immunity and the absence of available vaccines. The control is performed over a…

Optimization and Control · Mathematics 2024-06-12 Rocío Balderrama , Mariana Inés Prieto , Constanza Sánchez de la Vega , Federico Vazquez

The SEIR model is a compartmental model used to simulate the dynamics of an epidemic. In this chapter, we introduce two control functions in the compartmental SEIR model representing vaccination and plasma transfusion. Optimal control…

Optimization and Control · Mathematics 2021-07-23 Juliana Couras , Ivan Area , Juan J. Nieto , Cristiana J. Silva , Delfim F. M. Torres

The outbreak of mutant strains and vaccination behaviors have been the focus of recent epidemiological research, but most existing epidemic models failed to simultaneously capture viral mutation and consider the complexity and behavioral…

Populations and Evolution · Quantitative Biology 2026-01-16 Wenjie Zhang , Yusheng Li , Qin Li , Guojun Huang , Minyu Feng

This paper presents a discrete time probabilistic dynamic for simulating a contact-based epidemic spreading based on discrete time Markov chain process, in particular the attention is addressed to the susceptible-infectious-removed (SIR)…

Physics and Society · Physics 2017-12-22 Fabrizio Angaroni

We formalize and study the problem of optimal allocation strategies for a (perfect) vaccine in the infinite-dimensional SIS model. The question may be viewed as a bi-objective minimization problem, where one tries to minimize simultaneously…

Probability · Mathematics 2021-08-27 Jean-François Delmas , Dylan Dronnier , Pierre-André Zitt

We consider the simple epidemiological SIS model for a general heterogeneous population introduced by Lajmanovich and Yorke (1976) in finite dimension, and its infinite dimensional generalization we introduced in previous works. In this…

Dynamical Systems · Mathematics 2022-11-29 Jean-François Delmas , Dylan Dronnier , Pierre-André Zitt

How to prevent the spread of human diseases is a great challenge for the scientific community and so far there are many studies in which immunization strategies have been developed. However, these kind of strategies usually do not consider…

Physics and Society · Physics 2018-08-22 M. A. Di Muro , L. G. Alvarez-Zuzek , S. Havlin , L. A. Braunstein

During pandemic events, strategies such as social distancing can be fundamental to curb viral spreading. Such actions can reduce the number of simultaneous infections and mitigate the disease spreading, which is relevant to the risk of a…

Physics and Society · Physics 2021-02-24 Marco A. Amaral , Marcelo M. de Oliveira , Marco A. Javarone

Efficient testing and vaccination protocols are critical aspects of epidemic management. To study the optimal allocation of limited testing and vaccination resources in a heterogeneous contact network of interacting susceptible, recovered,…

Populations and Evolution · Quantitative Biology 2026-05-12 Mingtao Xia , Lucas Böttcher , Tom Chou

This paper investigates a behavioral-feedback SIR model in which the infection rate adapts dynamically based on the fractions of susceptible and infected individuals. We introduce an invariant of motion and we characterize the peak of…

Populations and Evolution · Quantitative Biology 2025-09-17 Martina Alutto , Leonardo Cianfanelli , Giacomo Como , Fabio Fagnani , Francesca Parise

We develop a mechanistic model that classifies individuals both in terms of epidemiological status (SIR) and vaccination attitude (willing or unwilling), with the goal of discovering how disease spread is influenced by changing opinions…

Dynamical Systems · Mathematics 2024-08-16 Yi Jiang , Kristin M. Kurianski , Jane HyoJin Lee , Yanping Ma , Daniel Cicala , Glenn Ledder

There are often multiple diseases with cross immunity competing for vaccination resources. Here we investigate the optimal vaccination program in a two-layer Susceptible-Infected-Removed (SIR) model, where two diseases with cross immunity…

Populations and Evolution · Quantitative Biology 2021-05-26 Yang Ye , Qingpeng Zhang , Zhidong Cao , Daniel Dajun Zeng

We numerically study the dynamics of the SIR disease model on small-world networks by using a large-deviation approach. This allows us to obtain the probability density function of the total fraction of infected nodes and of the maximum…

Physics and Society · Physics 2022-09-01 Yannick Feld , Alexander K. Hartmann

In the context of SARS-CoV-2 pandemic, mathematical modelling has played a fundamental role for making forecasts, simulating scenarios and evaluating the impact of preventive political, social and pharmaceutical measures. Optimal control…

Optimization and Control · Mathematics 2022-11-01 Giovanni Ziarelli , Luca Dede' , Nicola Parolini , Marco Verani , Alfio Quarteroni

Although modeling studies are focused on the control of SIR-based systems describing epidemic data sets (particularly the COVID-19), few of them present a formal dynamic characterization in terms of equilibrium sets and stability. Such…

Optimization and Control · Mathematics 2021-06-03 A. H. González , A. L. Anderson , A. Ferramosca , E. A. Hernandez-Vargas

Network-based epidemic models have been extensively employed to understand the spread of infectious diseases, but have generally overlooked the fact that most realistic networks are dynamical rather than static. In this paper, we study a…

Physics and Society · Physics 2019-02-19 Xiao-Long Peng , Ze-Qiong Zhang , Junyuan Yang , Zhen Jin

We study a simple model of epidemics where an infected node transmits the infection to its neighbors independently with probability $p$. This is also known as the independent cascade or Susceptible-Infected-Recovered (SIR) model with fixed…

Data Structures and Algorithms · Computer Science 2021-10-19 Yeganeh Alimohammadi , Christian Borgs , Amin Saberi

We study a multi-type SIR epidemic process among a heterogeneous population that interacts through a network. When we base social contact on a random graph with given vertex degrees, we give limit theorems on the fraction of infected…

Physics and Society · Physics 2021-11-02 Hamed Amini , Andreea Minca

To understand the impact of vaccination, we consider a SIVR (susceptible-infected-vaccinated-recovered) model which combines impulsive vaccination into the classical SIR model. The final size is firstly defined and estimated, and then the…

Populations and Evolution · Quantitative Biology 2024-10-29 Phyu Phyu Win , Zhigui Lin , Mengyun Zhang