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Revealing the structure of complex biological macromolecules, such as proteins, is an essential step for understanding the chemical mechanisms that determine the diversity of their functions. Synchrotron based x-ray crystallography and…
Magnetic resonance imaging (MRI) has greatly advanced neuroscience research and clinical diagnostics. However, imaging data collected across different scanners, acquisition protocols, or imaging sites often exhibit substantial…
Breast cancer is the most common malignancy in women. Mammographic findings such as microcalcifications and masses, as well as morphologic features of masses in sonographic scans, are the main diagnostic targets for tumor detection.…
Magnetic Resonance Imaging (MRI) is a non-invasive diagnostic and radiotherapy (RT) planning tool, offering detailed insights into the anatomy of the human body. The extensive scan time is stressful for patients, who must remain motionless…
The g-ratio, quantifying the comparative thickness of the myelin sheath encasing an axon, is a geometrical invariant that has high functional relevance because of its importance in determining neuronal conduction velocity. Advances in MRI…
Estimated brain age from magnetic resonance image (MRI) and its deviation from chronological age can provide early insights into potential neurodegenerative diseases, supporting early detection and implementation of prevention strategies.…
Medical images constitute a source of information essential for disease diagnosis, treatment and follow-up. In addition, due to its patient-specific nature, imaging information represents a critical component required for advancing…
Over the past several decades, many different types of computational imaging approaches have been proposed for improving MRI. In this paper, we provide an overview of methods that assume that MRI Fourier data is linearly predictable. Linear…
Diffusion Tensor Cardiac Magnetic Resonance (DT-CMR) is the only in vivo method to non-invasively examine the microstructure of the human heart. Current research in DT-CMR aims to improve the understanding of how the cardiac microstructure…
Multiple sclerosis (MS) is a chronic inflammatory and degenerative disease of the central nervous system, characterized by the appearance of focal lesions in the white and gray matter that topographically correlate with an individual…
In utero diffusion MRI provides unique opportunities to non-invasively study the microstructure of tissue during fetal development. A wide range of developmental processes, such as the growth of white matter tracts in the brain, the…
Magnetic resonance imaging (MRI) is a powerful technique for investigating the microscopic properties and dynamics of physical systems. In this work we demonstrate state-sensitive MRI of ultracold atoms in an optical lattice. Single-shot…
Magnetic resonance imaging (MRI) is a potent diagnostic tool for detecting pathological tissues in various diseases. Different MRI sequences have different contrast mechanisms and sensitivities for different types of lesions, which pose…
Multiple sclerosis (MS) is an inflammatory and neurodegenerative disease characterized by diffuse and focal areas of tissue loss. Conventional MRI techniques such as T1-weighted and T2-weighted scans are generally used in the diagnosis and…
The optimization of MRI data sampling and image reconstruction methods has been a priority for the MRI community since the very early days of the field. Designing an "optimal" method requires the definition of an optimality metric (i.e., a…
Microstructured materials, such as architected metamaterials and phononic crystals, exhibit complex wave propagation phenomena due to their internal structure. While full-scale numerical simulations can capture these effects, they are…
Learning-based approaches, especially those based on deep networks, have enabled high-quality estimation of tissue microstructure from low-quality diffusion magnetic resonance imaging (dMRI) scans, which are acquired with a limited number…
Parcellation of white matter tractography provides anatomical features for disease prediction, anatomical tract segmentation, surgical brain mapping, and non-imaging phenotype classifications. However, parcellation does not always reach…
Super-resolution microscopy overcomes the diffraction limit of conventional light microscopy in spatial resolution. By providing novel spatial or spatio-temporal information on biological processes at nanometer resolution with molecular…
Probing the transport of fluids within confined domains is important in many areas including material science, catalysis, food science, and cell biology. The diffusion propagator fully characterizes the diffusion process, which is highly…