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Physical limit of molecular sensing has been extensively studied in biological systems. Biosensors are engineered equivalents of molecular sensors in living systems and play critical role in disease diagnosis and management. Investigation…
Detail features of magnetic resonance images play a cru-cial role in accurate medical diagnosis and treatment, as they capture subtle changes that pose challenges for doc-tors when performing precise judgments. However, the widely utilized…
Diffusion magnetic resonance imaging is an imaging technology designed to probe anatomical architectures of biological samples in an in vivo and non-invasive manner through measuring water diffusion. The contribution of this paper is…
We introduce and demonstrate a new paradigm for quantitative parameter mapping in MRI. Parameter mapping techniques, such as diffusion MRI and quantitative MRI, have the potential to robustly and repeatably measure biologically-relevant…
Magnetic Resonance Fingerprinting (MRF) is a method to extract quantitative tissue properties such as T1 and T2 relaxation rates from arbitrary pulse sequences using conventional magnetic resonance imaging hardware. MRF pulse sequences have…
Biophysical models in diffusion MRI (dMRI) hold promise for characterizing gray matter tissue microstructure. Yet, the reliability of their parameter estimates remains largely under-studied, especially in models that incorporate water…
Microscopy is the workhorse of the physical and life sciences, producing crisp images of everything from atoms to cells well beyond the capabilities of the human eye. However, the analysis of these images is frequently little better than…
In vivo mapping of the neurite density with diffusion MRI (dMRI) is a high but challenging aim. First, it is unknown whether all neurites exhibit completely anisotropic ('stick-like') diffusion. Second, the 'density' of tissue components…
Atomic-resolution imaging with scanning transmission electron microscopy is a powerful tool for characterizing the nanoscale structure of materials, in particular features such as defects, local strains, and symmetry-breaking distortions.…
A feasibility study of microplastic detection and quantification in soil and water using resonance microwave reflectometry is carried out using artificially created samples with high volumetric concentration of microplastic with…
Morphological features of small vessels provide invaluable information regarding underlying tissue, especially in cancerous tumors. This paper introduces methods for obtaining quantitative morphological features from microvasculature images…
Magnetic Resonance Imaging (MRI) can be considered one of the most effective techniques in both clinical diagnostic medical field and biomedicine, as it allows to obtain images anatomy of the body and its various parts and information…
Studying learning-related plasticity is central to understanding the acquisition of complex skills, for example learning to master a musical instrument. Over the past three decades, conventional group-based functional magnetic resonance…
Magnetic resonance imaging (MRI) is indispensable for diagnosing and planning treatment in various medical conditions due to its ability to produce multi-series images that reveal different tissue characteristics. However, integrating these…
Magnetic resonance imaging (MRI) relies on radiofrequency (RF) excitation of proton spin. Clinical diagnosis requires a comprehensive collation of biophysical data via multiple MRI contrasts, acquired using a series of RF sequences that…
We review, systematize and discuss models of diffusion in neuronal tissue, by putting them into an overarching physical context of coarse-graining over an increasing diffusion length scale. From this perspective, we view research on…
Magnetic resonance imaging (MRI) is a remarkably powerful diagnostic technique: it generates wide-ranging information for the non-invasive study of tissue anatomy and physiology. Complementary data is normally obtained in separate…
Magnetic Resonance Imaging (MRI) is an essential diagnostic tool in clinical settings but its utility is often hindered by noise artifacts introduced during the imaging process. Effective denoising is critical for enhancing image quality…
Magnetic resonance imaging (MRI) is the non-invasive modality of choice for body tissue composition analysis due to its excellent soft tissue contrast and lack of ionizing radiation. However, quantification of body composition requires an…
Diffusion MRI is a modern neuroimaging modality with a unique ability to acquire microstructural information by measuring water self-diffusion at the voxel level. However, it generates huge amounts of data, resulting from a large number of…