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Despite remarkable performance in producing realistic samples, Generative Adversarial Networks (GANs) often produce low-quality samples near low-density regions of the data manifold, e.g., samples of minor groups. Many techniques have been…

Machine Learning · Computer Science 2021-10-28 Jinhee Lee , Haeri Kim , Youngkyu Hong , Hye Won Chung

We develop a new method for regularising neural networks. We learn a probability distribution over the activations of all layers of the model and then insert imputed values into the network during training. We obtain a posterior for an…

Machine Learning · Computer Science 2019-10-14 Matthew Willetts , Alexander Camuto , Stephen Roberts , Chris Holmes

Recently, it has become feasible to generate large-scale, multi-tissue gene expression data, where expression profiles are obtained from multiple tissues or organs sampled from dozens to hundreds of individuals. When traditional clustering…

Quantitative Methods · Quantitative Biology 2021-10-29 Pau Erola , Johan LM Björkegren , Tom Michoel

This paper proposes a new method to reverse engineer gene regulatory networks from experimental data. The modeling framework used is time-discrete deterministic dynamical systems, with a finite set of states for each of the variables. The…

Quantitative Methods · Quantitative Biology 2007-05-23 Reinhard Laubenbacher , Brandilyn Stigler

Unsupervised feature selection is an important method to reduce dimensions of high dimensional data without labels, which is benefit to avoid ``curse of dimensionality'' and improve the performance of subsequent machine learning tasks, like…

Machine Learning · Computer Science 2020-12-29 Yanyong Huang , Zongxin Shen , Fuxu Cai , Tianrui Li , Fengmao Lv

Gene expression datasets offer insights into gene regulation mechanisms, biochemical pathways, and cellular functions. Additionally, comparing gene expression profiles between disease and control patients can deepen the understanding of…

Machine Learning · Computer Science 2025-03-27 Rita T. Sousa , Heiko Paulheim

Time-series forecasting is one of the most active research topics in artificial intelligence. Applications in real-world time series should consider two factors for achieving reliable predictions: modeling dynamic dependencies among…

Machine Learning · Computer Science 2021-05-28 Gabriel Spadon , Shenda Hong , Bruno Brandoli , Stan Matwin , Jose F. Rodrigues-Jr , Jimeng Sun

Gene finding is the task of identifying the locations of coding sequences within the vast amount of genetic code contained in the genome. With an ever increasing quantity of raw genome sequences, gene finding is an important avenue towards…

Genomics · Quantitative Biology 2025-05-07 Frederikke I. Marin , Dennis Pultz , Wouter Boomsma

We have developed a Generative Recurrent Neural Networks (GRNN) that learns the probability of the next residue torsions $X_{i+1}=\ [\phi_{i+1},\psi_{i+1},\omega _{i+1}, \chi_{i+1}]$ from the previous residue in the sequence $X_i$ to…

Graph Neural Networks (GNNs) have enjoyed wide spread applications in graph-structured data. However, existing graph based applications commonly lack annotated data. GNNs are required to learn latent patterns from a limited amount of…

Machine Learning · Computer Science 2023-03-22 Wenqi Wei , Mu Qiao , Divyesh Jadav

Gene duplication is a fundamental evolutionary mechanism that contributes to biological complexity and diversity (Fortna et al., 2004). Traditionally, research has focused on the duplication of gene sequences (Zhang, 1914). However,…

Molecular Networks · Quantitative Biology 2024-05-07 Ashley Scruse , Jonathan Arnold , Robert Robinson

This paper presents a novel multi-fake evolutionary generative adversarial network(MFEGAN) for handling imbalance hyperspectral image classification. It is an end-to-end approach in which different generative objective losses are considered…

Image and Video Processing · Electrical Eng. & Systems 2024-09-04 Tanmoy Dam , Nidhi Swami , Sreenatha G. Anavatti , Hussein A. Abbass

Program synthesis aims to {\it automatically} find programs from an underlying programming language that satisfy a given specification. While this has the potential to revolutionize computing, how to search over the vast space of programs…

Neural and Evolutionary Computing · Computer Science 2022-03-01 Yuan Yuan , Wolfgang Banzhaf

Deep neural network-based architectures give promising results in various domains including pattern recognition. Finding the optimal combination of the hyper-parameters of such a large-sized architecture is tedious and requires a large…

Computer Vision and Pattern Recognition · Computer Science 2020-03-17 Animesh Singh , Sandip Saha , Ritesh Sarkhel , Mahantapas Kundu , Mita Nasipuri , Nibaran Das

Determining mechanistic models of gene regulation, especially underlying phenotypic variation, is a central goal of both mathematical biology and modern evolutionary biology. However, several challenges, involving both common…

Molecular Networks · Quantitative Biology 2025-11-04 Cody E. FitzGerald , Shelley Reich , Victor Agaba , Arjun Mathur , Michael S. Werner , Niall M. Mangan

In evolutionary computation, it is commonly assumed that a search algorithm acquires knowledge about a problem instance by sampling solutions from the search space and evaluating them with a fitness function. This is necessarily inefficient…

Neural and Evolutionary Computing · Computer Science 2024-11-12 Piotr Wyrwiński , Krzysztof Krawiec

The paper presents an experimental study of resilient path planning for con-tinuum robots taking into account the multi-objective optimisation problem. To do this, we used two well-known algorithms, namely Genetic algorithm and A*…

Robotics · Computer Science 2024-11-06 Oxana Shamilyan , Ievgen Kabin , Zoya Dyka , Peter Langendoerfer

Generative adversarial nets (GANs) have been remarkably successful at learning to sample from distributions specified by a given dataset, particularly if the given dataset is reasonably large compared to its dimensionality. However, given…

Machine Learning · Computer Science 2022-11-29 Tiantian Fang , Ruoyu Sun , Alex Schwing

Machine Learning methods have of late made significant efforts to solving multidisciplinary problems in the field of cancer classification using microarray gene expression data. Feature subset selection methods can play an important role in…

Computational Engineering, Finance, and Science · Computer Science 2013-03-04 G. Prat , Ll. Belanche

Generative adversarial networks (GANs) are successful deep generative models. GANs are based on a two-player minimax game. However, the objective function derived in the original motivation is changed to obtain stronger gradients when…

Machine Learning · Statistics 2016-11-10 Masatoshi Uehara , Issei Sato , Masahiro Suzuki , Kotaro Nakayama , Yutaka Matsuo