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Model-based clustering is widely used for identifying and distinguishing types of diseases. However, modern biomedical data coming with high dimensions make it challenging to perform the model estimation in traditional cluster analysis. The…

Methodology · Statistics 2025-07-22 Kazeem Kareem , Fan Dai

Feature selection is an important and challenging task in high dimensional clustering. For example, in genomics, there may only be a small number of genes that are differentially expressed, which are informative to the overall clustering…

Methodology · Statistics 2019-10-07 Xiangrui Zeng , Hongyu Zheng

With rapidly increasing data, clustering algorithms are important tools for data analytics in modern research. They have been successfully applied to a wide range of domains; for instance, bioinformatics, speech recognition, and financial…

Data Structures and Algorithms · Computer Science 2015-12-01 Ka-Chun Wong

One important tool is the optimal clustering of data into useful categories. Dividing similar objects into a smaller number of clusters is of importance in many applications. These include search engines, monitoring of academic performance,…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-09-21 Gavriel Yarmish , Philip Listowsky , Simon Dexter

Leukemia is a hematologic cancer which develops in blood tissue and triggers rapid production of immature and abnormal shaped white blood cells. Based on statistics it is found that the leukemia is one of the leading causes of death in men…

Computer Vision and Pattern Recognition · Computer Science 2018-03-28 Sachin Kumar , Sumita Mishra , Pallavi Asthana , Pragya

Chromatin conformation capture technologies such as Hi-C have revealed that the genome is organized in a hierarchy of structures spanning multiple scales observed at different resolutions. Current algorithms often focus on specific…

Genomics · Quantitative Biology 2025-12-22 Vipin Kumar , Roberto Rossini , Jonas Paulsen , Anthony Mathelier

Common clustering algorithms require multiple scans of all the data to achieve convergence, and this is prohibitive when large databases, with data arriving in streams, must be processed. Some algorithms to extend the popular K-means method…

Applications · Statistics 2017-12-22 Giacomo Aletti , Alessandra Micheletti

Discrete mixture models provide a well-known basis for effective clustering algorithms, although technical challenges have limited their scope. In the context of gene-expression data analysis, a model is presented that mixes over a finite…

Methodology · Statistics 2012-11-12 Michael A. Newton , Lisa M. Chung

A fundamental task in human chromosome analysis is chromosome segmentation. Segmentation plays an important role in chromosome karyotyping. The first step in segmentation is to remove intrusive objects such as stain debris and other noises.…

Computer Vision and Pattern Recognition · Computer Science 2014-09-02 Shervin Minaee , Mehran Fotouhi , Babak Hossein Khalaj

Clustering analysis is of substantial significance for data mining. The properties of big data raise higher demand for more efficient and economical distributed clustering methods. However, existing distributed clustering methods mainly…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-07-03 Yifeng Xiao , Jiang Xue , Deyu Meng

We propose a simple and efficient clustering method for high-dimensional data with a large number of clusters. Our algorithm achieves high-performance by evaluating distances of datapoints with a subset of the cluster centres. Our…

Machine Learning · Computer Science 2022-03-30 Georgios Exarchakis , Omar Oubari , Gregor Lenz

A new approach to clustering, based on the physical properties of inhomogeneous coupled chaotic maps, is presented. A chaotic map is assigned to each data-point and short range couplings are introduced. The stationary regime of the system…

Statistical Mechanics · Physics 2009-10-31 L. Angelini , F. De Carlo , C. Marangi , M. Pellicoro , S. Stramaglia

We present a novel coupled two-way clustering approach to gene microarray data analysis. The main idea is to identify subsets of the genes and samples, such that when one of these is used to cluster the other, stable and significant…

Biological Physics · Physics 2009-11-06 G. Getz , E. Levine , E. Domany

In this paper we present the results of unstructured data clustering in this case a textual data from Reuters 21578 corpus with a new biomimetic approach using immune system. Before experimenting our immune system, we digitalized textual…

Artificial Intelligence · Computer Science 2012-10-29 Mohamed Hamou , Abdelmalek Amine , Ahmed Chaouki Lokbani

The problem of data clustering is one of the most important in data analysis. It can be problematic when dealing with experimental data characterized by measurement uncertainties and errors. Our paper proposes a recursive scheme for…

Machine Learning · Computer Science 2024-01-12 Alicja Miniak-Górecka , Krzysztof Podlaski , Tomasz Gwizdałła

A hierarchical scheme for clustering data is presented which applies to spaces with a high number of dimension ($N_{_{D}}>3$). The data set is first reduced to a smaller set of partitions (multi-dimensional bins). Multiple clustering…

Data Analysis, Statistics and Probability · Physics 2017-10-16 Kevin McIlhany , Stephen Wiggins

We introduce a new method for performing clustering with the aim of fitting clusters with different scatters and weights. It is designed by allowing to handle a proportion $\alpha$ of contaminating data to guarantee the robustness of the…

Statistics Theory · Mathematics 2008-12-18 Luis A. García-Escudero , Alfonso Gordaliza , Carlos Matrán , Agustin Mayo-Iscar

A first step in exploring population structure in crop plants and other organisms is to define the number of subpopulations that exist for a given data set. The genetic marker data sets being generated have become increasingly large over…

Applications · Statistics 2014-01-09 Mark A. Newell , Dianne Cook , Heike Hofmann , Jean-Luc Jannink

Deep learning has empowered analysis for single-cell sequencing data in many ways and has generated deep understanding about a range of complex cellular systems. As the booming single-cell sequencing technologies brings the surge of high…

Genomics · Quantitative Biology 2021-04-27 Yang Xu , Andrew Jeremiah Strick

Genomes may be analyzed from an information viewpoint as very long strings, containing functional elements of variable length, which have been assembled by evolution. In this work an innovative information theory based algorithm is…

Genomics · Quantitative Biology 2020-09-23 Vincenzo Bonnici , Giuditta Franco , Vincenzo Manca