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It is becoming widely accepted that very early in the origin of life, even before the emergence of genetic encoding, reaction networks of diverse small chemicals might have manifested key properties of life, namely self-propagation and…

Populations and Evolution · Quantitative Biology 2023-01-05 Zhen Peng , Alex Plum , Praful Gagrani , David A. Baum

A common trait of complex systems is that they can be represented by means of a network of interacting parts. It is, in fact, the network organisation (more than the parts) what largely conditions most higher-level properties, which are not…

Populations and Evolution · Quantitative Biology 2019-07-15 Ricard Sole , Sergi Valverde

As intelligent systems are developed across diverse substrates - from machine learning models and neuromorphic hardware to in vitro neural cultures - understanding what gives a system agency has become increasingly important. Existing…

Neurons and Cognition · Quantitative Biology 2026-01-08 Brett J. Kagan , Valentina Baccetti , Brian D. Earp , J. Lomax Boyd , Julian Savulescu , Adeel Razi

Emergent communication offers insight into how agents develop shared structured representations, yet most research assumes homogeneous modalities or aligned representational spaces, overlooking the perceptual heterogeneity of real-world…

Multiagent Systems · Computer Science 2026-01-30 Naomi Pitzer , Daniela Mihai

What role does phenotypic complexity play in the systems-level function of an embodied agent? The organismal phenotype is a topologically complex structure that interacts with a genotype, developmental physics, and an informational…

Neurons and Cognition · Quantitative Biology 2022-08-15 Bradly Alicea , Jesse Parent

This letter seeks to illuminate the profound connection between complexity, self-organization, emergent behaviour, pattern formation, and entropy concepts that are foundational to understanding our universe. By examining these ideas through…

Adaptation and Self-Organizing Systems · Physics 2025-03-25 Vinesh Vijayan , Karpagavalli K , Sandhiya Jenifer J , Prakash R

When dealing with evolving or multi-dimensional complex systems, network theory provides with elegant ways of describing their constituting components, through respectively time-varying and multi-layer complex networks. Nevertheless, the…

Physics and Society · Physics 2018-02-13 Massimiliano Zanin , Ernestina Menasalvas , Xiaoqian Sun , Sebastian Wandelt

Single-cell RNA-seq foundation models achieve strong performance on downstream tasks but remain black boxes, limiting their utility for biological discovery. Recent work has shown that sparse dictionary learning can extract concepts from…

Genomics · Quantitative Biology 2025-10-31 Charlotte Claye , Pierre Marschall , Wassila Ouerdane , Céline Hudelot , Julien Duquesne

Ecology studies biodiversity in its variety and complexity. It describes how species distribute and perform in response to environmental changes. Ecological processes and structures are highly complex and adaptive. In order to quantify…

Populations and Evolution · Quantitative Biology 2013-10-09 Cang Hui

Animals smelling in the real world use a small number of receptors to sense a vast number of natural molecular mixtures, and proceed to learn arbitrary associations between odors and valences. Here, we propose a new interpretation of how…

Neurons and Cognition · Quantitative Biology 2017-07-10 Kamesh Krishnamurthy , Ann M Hermundstad , Thierry Mora , Aleksandra M Walczak , Vijay Balasubramanian

The cell cycle is a tightly controlled process, yet its underlying genetic network shows marked differences across species. Which of the associated structural features follow solely from the ability to impose the appropriate gene expression…

Molecular Networks · Quantitative Biology 2015-06-12 M. Zagorski , A. Krzywicki , O. C. Martin

Scientometric data is used to investigate empirically the emergence of search regimes in Biotechnology, Genomics, and Nanotechnology. Complex regimes can emerge when three independent sources of variance interact. In our model, researchers…

Adaptation and Self-Organizing Systems · Physics 2011-01-14 Gaston Heimeriks , Loet Leydesdorff

1) Micro-evolutionary predictions are complicated by ecological feedbacks like density dependence, while ecological predictions can be complicated by evolutionary change. A widely used approach in micro-evolution, quantitative genetics,…

Populations and Evolution · Quantitative Biology 2015-09-07 Tim Coulson , Floriane Plard , Susanne Schindler , Arpat Ozgul , Jean-Michel Gaillard

Spatial ecological networks are widely used to model interactions between georeferenced biological entities (e.g., populations or communities). The analysis of such data often leads to a two-step approach where groups containing similar…

Applications · Statistics 2014-02-24 Vincent Miele , Franck Picard , Stéphane Dray

As the first step in an investigation of the origin of genetic information, we study how some species of molecules are preserved over cell generations and play an important role in controlling the growth of a cell. We consider a model…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 Kunihiko Kaneko , Tetsuya Yomo

In any ecosystem, the conditions of the environment and the characteristics of the species that inhabit it are entangled, co-evolving in space and time. We introduce a model that couples active agents with a dynamic environment, interpreted…

Populations and Evolution · Quantitative Biology 2025-12-10 G. Briozzo , G. J. Sibona , F. Peruani

Entity Recognition (ER) within a text is a fundamental exercise in Natural Language Processing, enabling further depending tasks such as Knowledge Extraction, Text Summarisation, or Keyphrase Extraction. An entity consists of single words…

Computation and Language · Computer Science 2021-06-14 Andreas Waldis , Luca Mazzola

The success of smart environments largely depends on their smartness of understanding the environments' ongoing situations. Accordingly, this task is an essence to smart environment central processors. Obtaining knowledge from the…

Human-Computer Interaction · Computer Science 2019-06-25 Hossein Rajaby Faghihi , Mohammad Amin Fazli , Jafar Habibi

The possibility that evolutionary forces -- together with a few fundamental factors such as thermodynamic constraints, specific computational features enabling information processing, and ecological processes -- might constrain the logic of…

Biological Physics · Physics 2025-12-30 Manlio De Domenico

This paper introduces a framework for modeling cyclical and feedback-driven information flow through a generalized family of entropy-modulated transformations called derangetropy functionals. Unlike scalar and static entropy measures such…

Information Theory · Computer Science 2025-06-17 Masoud Ataei , Xiaogang Wang
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