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Motivation: Predicting the secondary structure of an RNA sequence is useful in many applications. Existing algorithms (based on dynamic programming) suffer from a major limitation: their runtimes scale cubically with the RNA length, and…

Biomolecules · Quantitative Biology 2020-01-14 Liang Huang , He Zhang , Dezhong Deng , Kai Zhao , Kaibo Liu , David A. Hendrix , David H. Mathews

This is a survey on the use of low-degree polynomials to predict and explain the apparent statistical-computational tradeoffs in a variety of average-case computational problems. In a nutshell, this framework measures the complexity of a…

Statistics Theory · Mathematics 2025-06-13 Alexander S. Wein

In the last decade, there has been a substantial amount of research in finding routing algorithms designed specifically to run on real-world graphs. In 2010, Abraham et al. showed upper bounds on the query time in terms of a graph's highway…

Data Structures and Algorithms · Computer Science 2015-09-08 Colin White

Large language models are powerful generalists, yet solving deep and complex problems such as those of the Humanity's Last Exam (HLE) remains both conceptually challenging and computationally expensive. We show that small orchestrators…

This research is to search for alternatives to the resolution of complex medical diagnosis where human knowledge should be apprehended in a general fashion. Successful application examples show that human diagnostic capabilities are…

Neural and Evolutionary Computing · Computer Science 2010-09-28 Abu Bakar Siddiquee , Md. Ehsanul Hoque Mazumder , S. M. Kamruzzaman

We study a propositional variant of Hoare logic that can be used for reasoning about programs that exhibit both angelic and demonic nondeterminism. We work in an uninterpreted setting, where the meaning of the atomic actions is specified…

Logic in Computer Science · Computer Science 2019-03-14 Konstantinos Mamouras

Inspired by the trend on unifying theories of programming, this paper shows how the algebraic treatment of standard data dependency theory equips relational data with functional types and an associated type system which is useful for type…

Logic in Computer Science · Computer Science 2012-10-18 Jose N. Oliveira

Understanding the principles of protein folding is a cornerstone of computational biology, with implications for drug design, bioengineering, and the understanding of fundamental biological processes. Lattice protein folding models offer a…

Disordered Systems and Neural Networks · Physics 2025-08-08 Shoummo Ahsan Khandoker , Estelle M. Inack , Mohamed Hibat-Allah

The purpose of this survey is to serve both as a gentle introduction and a coherent overview of state-of-the-art Frank--Wolfe algorithms, also called conditional gradient algorithms, for function minimization. These algorithms are…

The general completeness problem of Hoare logic relative to the standard model $N$ of Peano arithmetic has been studied by Cook, and it allows for the use of arbitrary arithmetical formulas as assertions. In practice, the assertions would…

Logic in Computer Science · Computer Science 2017-03-02 Zhaowei Xu , Wenhui Zhang , Yuefei Sui

Many state-of-the-art Segment Routing (SR) Traffic Engineering (TE) algorithms rely on Linear Program (LP)-based optimization. However, the poor scalability of the latter and the resulting high computation times impose severe restrictions…

Networking and Internet Architecture · Computer Science 2024-08-27 Alexander Brundiers , Timmy Schüller , Nils Aschenbruck

Formal verification provides strong guarantees of correctness of software, which are especially important in safety or security critical systems. Hoare logic is a widely used formalism for rigorous verification of software against…

Programming Languages · Computer Science 2021-03-11 Jayaraj Poroor

The proposed approach is to formalise the probabilistic puzzle in equational FOL. Two formalisations are needed: one theory for all models of the given puzzle, and a second theory for the favorable models. Then Mace4 - that computes all the…

Artificial Intelligence · Computer Science 2023-05-22 Adrian Groza

An algebraic multilevel iteration method for solving system of linear algebraic equations arising in $H(\mathrm{curl})$ and $H(\mathrm{div})$ spaces are presented. The algorithm is developed for the discrete problem obtained by using the…

Numerical Analysis · Mathematics 2013-12-02 S. K. Tomar

Importance measures provide a systematic approach to scrutinize critical system components, which are extremely beneficial in making important decisions, such as prioritizing reliability improvement activities, identifying weak-links and…

Formal Languages and Automata Theory · Computer Science 2019-04-04 Waqar Ahmed , Shahid Ali Murtza , Osman Hasan , Sofiene Tahar

This paper presents a novel framework for the modeling of biological networks. It makes use of recent tools analyzing the robust satisfaction of properties of (hybrid) dynamical systems. The main challenge of this approach as applied to…

Computational Engineering, Finance, and Science · Computer Science 2012-08-22 Nicolas Mobilia , Alexandre Donzé , Jean Marc Moulis , Éric Fanchon

We propose a novel rank-adaptive higher-order orthogonal iteration (HOOI) algorithm to compute the truncated Tucker decomposition of higher-order tensors with a given error tolerance, and prove that the method is locally optimal and…

Numerical Analysis · Mathematics 2021-10-26 Chuanfu Xiao , Chao Yang

This paper is concerned with the approximation of tensors using tree-based tensor formats, which are tensor networks whose graphs are dimension partition trees. We consider Hilbert tensor spaces of multivariate functions defined on a…

Numerical Analysis · Mathematics 2019-09-11 Anthony Nouy

Construction of neural network architectures suitable for learning from both continuous and discrete tabular data is a challenging research endeavor. Contemporary high-dimensional tabular data sets are often characterized by a relatively…

Machine Learning · Computer Science 2025-02-14 Boshko Koloski , Nada Lavrač , Blaž Škrlj

Explanation methods shed light on the decision process of black-box classifiers such as deep neural networks. But their usefulness can be compromised because they are susceptible to manipulations. With this work, we aim to enhance the…

Machine Learning · Computer Science 2020-12-21 Ann-Kathrin Dombrowski , Christopher J. Anders , Klaus-Robert Müller , Pan Kessel
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